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Table 3 Histopathological scoring of the paracetamol-induced liver injury pre-treated with various doses of MEMM in rats

From: Methanol extract of Melastoma malabathricum leaves exerted antioxidant and liver protective activity in rats

Treatment Dose (mg/kg) Steatosis Necrosis Inflammation Haemorrhage
Control - - - - -
10% DMSO + Paracetamol   - +++ ++ ++
Silymarin + Paracetamol 200 - + + +
MEMM + Paracetamol 50 - ++ + ++
250 - + + +
  500 - - + +
  1. The severity of various features of hepatic injury was evaluated based on those following scoring scheme: - normal, + mild effect, ++ moderate effect, +++ severe effect.