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Table 1 Final body weight, body weight gain, and water consumption of rats treated with different doses of the C. langsdorffii extract and/or DMH and their respective controls, for the comet assay

From: Chemopreventive effect of Copaifera langsdorffii leaves hydroalcoholic extract on 1,2-dimethylhydrazine-induced DNA damage and preneoplastic lesions in rat colon

Treatments (mg/kg) Final body weight (g)* Body weight gain (g)* Water consumption*a
EDTA 166.8 ± 11.6 54.5 ± 7.9 36.9 ± 5.6
DMSO 170.6 ± 11.0 51.1 ± 6.3 41.5 ± 4.7
80 167.5 ± 11.0 54.6 ± 5.8 40.6 ± 7.4
DMH 165.0 ± 11.3 52.6 ± 7.4 37.2 ± 6.5
DMSO + DMH 168.1 ± 10.4 56.6 ± 7.6 44.6 ± 12.3
20 + DMH 167.1 ± 11.4 52.3 ± 9.3 37.9 ± 5.8
40 + DMH 168.1 ± 11.3 49.3 ± 6.3 37.5 ± 6.8
80 + DMH 169.6 ± 10.2 53.3 ± 6.9 45.5 ± 7.2
  1. EDTA, vehicle control; DMH, 1,2-dimethylhydrazine (40 mg/kg); DMSO, dimethylsulfoxide (0.6 g/kg). The numbers 20, 40, and 80 correspond to the extract dose in mg/kg.
  2. *Values are the mean ± standard deviation.
  3. aWater consumption calculated in mL per animal per day.