Table 2 Effect of OPLE on renal functional parameters

Renal blood flow (ml min^-1 g^-1 kidney)

1.43 ± 0.10

1.66 ± 0.15

2.28 ± 0.39

2.49 ± 0.17^aaa

1.73 ± 0.32

2.52 ± 0.19^aaa

Glomerular filtration rate (ml min^-1 g^-1 kidney)

0.61 ± 0.06

0.47 ± 0.06

0.96 ± 0.04^aaa

0.80 ± 0.05^a

0.62 ± 0.06^bb

1.06 ± 0.14^aaa,b

Urine flow rate (μl min^-1 g^-1 kidney)

3.75 ± 0.59

2.72 ± 0.36

10.68 ± 1.30^aaa

7.32 ± 0.57^aaa

5.40 ± 0.68^bb

10.88 ± 0.98^aaa,bb

Urinary protein excretion (mg 2hr^-1)

1.33 ± 0.03

1.08 ± 0.02

6.83 ± 0.30^aaa

3.72 ± 0.30^aa

1.77 ± 0.17^bbb

5.99 ± 0.44^aaa,bb

Fractional sodium excretion (%)

0.63 ± 0.19

0.50 ± 0.08

1.34 ± 0.34

0.91 ± 0.20

1.77 ± 0.17^bbb

5.99 ± 0.44^aaa,bb