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Table 1 The effects of BU-derived sub-fractions in aortic rings precontracted with PE or KCl

From: Potassium channel openers and prostacyclin play a crucial role in mediating the vasorelaxant activity of Gynura procumbens

Fraction

PE

KCl

 

Rmax(%)

pIC50

Rmax(%)

pIC50

1

98.39 ± 5.79*

2.62 ± 0.09*

84.40 ± 24.04

2.54 ± 0.15

2

56.57 ± 20.90

2.04 ± 0.35

69.54 ± 18.08

2.34 ± 0.18

3

67.21 ± 12.33

2.24 ± 0.08

57.45 ± 13.09

2.13 ± 0.15

4

14.02 ± 3.92

-

24.54 ± 8.67

-

5

32.47 ± 9.12

-

43.01 ± 6.93

-

6

24.35 ± 8.74

-

15.15 ± 3.72

-

7

7.84 ± 1.57

-

12.85 ± 3.52

-

8

11.38 ± 2.75

-

18.38 ± 4.99

-

  1. Values are means ± S.E.M (n = 6). *P < 0.05 compared with other sub-fractions.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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