From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Ā | Ā | Main study | Reversibility study | ||||
---|---|---|---|---|---|---|---|
Treatment | Dose (mg/kg) | Sperm motility (%) | Sperm count (million/ml) | Abnormality (%) | Sperm motility (%) | Sperm counted (million/ml) | Abnormality (%) |
Distilled water | (10 ml/kg) | 85.00āĀ±ā6.00 | 31.14āĀ±ā2.50 | 5.14āĀ±ā1.10 | 81.60āĀ±ā7.17 | 25.80āĀ±ā4.28 | 7.20āĀ±ā1.72 |
DAS-77 | 80 | 73.43āĀ±ā12.61 | 25.57āĀ±ā4.07 | 8.86āĀ±ā2.42 | 72.33āĀ±ā9.30 | 24.67āĀ±ā3.53 | 8.33āĀ±ā2.01 |
DAS-77 | 400 | 87.29āĀ±ā12.05 | 33.00āĀ±ā3.52 | 4.14āĀ±ā1.44 | 70.80āĀ±ā9.07 | 23.00āĀ±ā2.54 | 7.40āĀ±ā1.50 |
DAS-77 | 2000 | 42.71āĀ±ā10.33* | 14.71āĀ±ā3.00** | 12.43āĀ±ā2.26* | 74.25āĀ±ā13.56 | 25.50āĀ±ā5.52 | 5.50āĀ±ā1.71 |