From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Reversibility study | |||||
---|---|---|---|---|---|---|---|
Ā | Ā | GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) |
Distilled water | (10 ml/kg) | 1.45āĀ±ā0.22 | 3.24āĀ±ā0.33 | 14.94āĀ±ā1.54 | 0.10āĀ±ā0.10 | 0.19āĀ±ā0.02 | 34.68āĀ±ā1.91 |
DAS-77 | 80 | 3.69āĀ±ā0.55*** | 5.82āĀ±ā0.72** | 26.87āĀ±ā3.33** | 1.83āĀ±ā0.23** | 0.19āĀ±ā0.02 | 24.41āĀ±ā2.52** |
DAS-77 | 400 | 1.70āĀ±ā0.31 | 3.62āĀ±ā0.56 | 16.72āĀ±ā2.58 | 1.14āĀ±ā0.18 | 0.22āĀ±ā0.01 | 24.35āĀ±ā1.40* |
DAS-77 | 2000 | 2.29āĀ±ā0.15 | 3.71āĀ±ā0.14 | 17.10āĀ±ā0.64 | 1.17āĀ±ā0.04 | 0.93āĀ±ā0.81 | 33.10āĀ±ā3.66 |