From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Main study | |||||
---|---|---|---|---|---|---|---|
Ā | Ā | GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) |
Distilled water | (10 ml/kg) | 1.69āĀ±ā0.15 | 3.41āĀ±ā0.73 | 17.66āĀ±ā5.22 | 1.26āĀ±ā0.34 | 0.27āĀ±ā0.08 | 28.94āĀ±ā5.64 |
DAS-77 | 80 | 2.76āĀ±ā0.83 | 12.31āĀ±ā3.01 | 58.21āĀ±ā13.80** | 3.96āĀ±ā0.94 | 0.11āĀ±ā0.03* | 50.22āĀ±ā10.34 |
DAS-77 | 400 | 2.12āĀ±ā0.21 | 7.69āĀ±ā0.53 | 35.46āĀ±ā2.43 | 2.32āĀ±ā0.15 | 0.07āĀ±ā0.02** | 51.13āĀ±ā3.57 |
DAS-77 | 2000 | 2.17āĀ±ā0.18 | 9.63āĀ±ā1.03 | 44.41āĀ±ā4.75* | 3.02āĀ±ā0.32 | 0.13āĀ±ā0.03* | 35.22āĀ±ā2.57 |