Table 3 Effect of test materials and propanolol (reference control) on heart rate of rats
Group | Dose (mg/kg bw.) | Heart rate (beat/min) | ||
|---|---|---|---|---|
| Â | Â | Before induction of hypertension | After induction of hypertension | After treatment of hypertension |
Normal | - | 412 ± 4.3 | 415 ± 4.1 | 409 ± 4.5 |
Untreated control | - | 399 ± 4.1 | 535 ± 5.4 | 570 ± 5.8 |
Propanolol-treated | 10 | 410 ± 4.4 | 520 ± 5.5 | 405 ± 4.4 |
CUR | 1000 | 411 ± 4.5 | 530 ± 5.5 | 530 ± 5.5 |
|  | 3000 | 401 ± 4.2 | 528 ± 5.3 | 518 ± 5.6 |
|  | 5000 | 390 ± 3.9 | 523 ± 5.4 | 471 ± 4.3 |
ZO | 1000 | 420 ± 4.2 | 526 ± 4.9 | 499 ± 5.1 |
|  | 3000 | 418 ± 4.9 | 531 ± 5.7 | 474 ± 5.2 |
|  | 5000 | 415 ± 4.6 | 530 ± 5.5 | 416 ± 4.1* |
AL | 1000 | 403 ± 4.1 | 544 ± 5.4 | 431 ± 4.4* |
|  | 3000 | 407 ± 4.3 | 540 ± 5.6 | 416 ± 4.3* |
|  | 5000 | 398 ± 3.6 | 528 ± 5.3 | 410 ± 4.5* |
PC | 100 | 409 ± 4.0 | 537 ± 5.2 | 540 ± 5.6 |
|  | 500 | 410 ± 4.2 | 519 ± 5.3 | 427 ± 4.1* |
|  | 1000 | 420 ± 4.5 | 509 ± 5.3 | 419 ± 4.6* |
PPF | 1000 | 412 ± 4.5 | 519 ± 5.2 | 559 ± 5.8 |
|  | 2000 | 398 ± 4.7 | 534 ± 5.6 | 544 ± 5.7 |
|  | 4000 | 405 ± 4.4 | 526 ± 5.5 | 536 ± 5.4 |