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Table 3 Effect of CCE on several serum parameters with/without CDDP treatment

From: Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

Parameter Experimental groups
  Control CCE CDDP 15 days CDDP + CCE (pre-treatment) CDDP + CCE (post-treatment) CDDP 30 days CDDP + CCE (pre-treatment) CDDP + CCE (post-treatment)
Creatinine (mg/dl) 0,8 ± 0,14 0,75 ± 0,1 1,79 ± 0,0045* 0,56 ± 0,005* 0,88 ± 0,0048* 2,13 ± 0,005* 0,87 ± 0,0044 0,95 ± 0,0052
Urea (mg/dl) 52,34 ± 0,12 51,54 ± 0,17 79,13 ± 0,12* 58,5 ± 0,14* 60,13 ± 0,19* 94,2 ± 0,12* 60,12 ± 0,18 68,5 ± 0,15
Albumin (g/dl) 10,44 ± 0,14 10,72 ± 0,15 8,01 ± 0,17* 9,8 ± 0,14* 8,48 ± 0,18* 7,12 ± 0,16* 9,91 ± 0,12 9,24 ± 0,16
Total protein (g/dl) 9,95 ± 0,19 9,78 ± 0,21 7,12 ± 0,25* 8,67 ± 0,19* 8,03 ± 0,26* 6,2 ± 0,193* 8,7 ± 0,23 8,12 ± 0,26
  1. Experimental values are expressed as mean ± SD. Comparison of mean values between groups was performed by one way-analysis of variance (oneway-ANOVA) (*) significantly different from control at p<0.05.