The effect of CTCM on the change in the respiratory resistance (ratio) after allergen challenge in OVA-sensitized asthmatic guinea pigs. (A) Overview of the 6-hr period. Comparison between the NSGP, SGP and MSGP groups. (B) Comparison of the different groups of sensitized animals in the first hour (repeated measures ANOVA with a Mauchly post-hoc test, sensitized vs. unsensitized; **P < 0.01). NSGP: unsensitized animals with challenge; SGP: sensitized animals with challenge; MSGP: sensitized animals with CTCM treatment 5 min before challenge; SMGP: sensitized animals with CTCM treatment 10 min after challenge. Each point represents the mean of the data from 10 animals and the restical bars represent standard deviation.