Table 1 Characteristics of included CAM RCTs
Intervention | Sample Size Median (Q1-Q3), Total | Double-blind No. (%) | Significant results for efficacy No. (%) | Industry funded No. (%) | Longest duration to follow up ≥ 6 m, No. (%) | Paediatric population No. (%) | Therapeutic studies No. (%) | Combined Studies No. (%) | Multicenter trials No. (%) | Journal IF > 5, No. (%) |
|---|---|---|---|---|---|---|---|---|---|---|
Acupuncture, n = 75 | 60 (32-102) 8,717 | 16 (21) | 58 (77) | 5 (7) | 9 (12) | 4 (5) | 71 (95) | 23 (31) | 11 (15) | 9 (12) |
Chinese herbal Medicine, n = 46 | 71 (48-98) 6,170 | 20 (43) | 36 (78) | 3 (6.5) | 6 (13) | 2 (4) | 32 (70) | 12 (26) | 11 (24) | 1 (2) |
Chiropractic, n = 6 | 32 (28-47) 402 | 1 (17) | 4 (67) | 1 (17) | 1 (17) | - | 5 (83) | 2 (33) | 1 (17) | - |
Coenzyme Q-10, n = 8 | 56 (34-166) 789 | 8 (100) | 6 (75) | 2 (25) | 4 (50) | 2 (25) | 5 (63) | - | 1 (13) | 2 (25) |
Combination herbal products, n = 11 | 85 (52-97) 882 | 9 (82) | 6 (55) | 6 (55) | 2 (18) | 1 (9) | 9 (82) | 1 (9) | 3 (27) | - |
Fish oil/Omega 3, n = 29 | 64 (33-105) 2,671 | 25 (86) | 14 (48) | 7 (24) | 10 (34) | 4 (14) | 14 (48) | 6 (21) | 3 (10) | 2 (7) |
Flax Seed, n = 6 | 48 (38-68) 321 | 4 (67) | 4 (67) | 1 (17) | 1 (17) | - | 2 (33) | - | - | - |
Garlic supplements, n = 2 | 542 (303-780) 1,083 | 2 (100) | 2 (100) | 1 (50) | 2 (100) | - | - | 1 (50) | - | - |
Gingko Biloba, n = 4 | 80 (56-835) 3,243 | 2 (50) | 2 (50) | 1 (25) | 1 (25) | - | 3 (75) | - | 1 (25) | 1 (25) |
Ginseng, n = 6 | 62 (30-85) 394 | 5 (83) | 2 (33) | 3 (50) | 1 (17) | - | 2 (33) | 1 (17) | - | 2 (33) |
Glucosamine, n = 3 | 22 (19-122) 260 | 1 (33) | 2 (67) | - | 2 (67) | - | 3 (100) | - | 1 (33) | - |
Massage, n = 1 | - 35 | 1 (100) | 1 (100) | - | - | - | - | - | - | - |
Traditional medicine, n = 8 | 66 (48-108) 643 | 5 (63) | 7 (88) | 2 (25) | - | - | 6 (75) | 1 (13) | 3 (38) | - |
TOTAL, (n = 205) | 63 (36-100) 25,610 | 99 (48) | 144 (70) | 33 (16) | 39 (19) | 13 (6) | 152 (74) | 47 (23) | 35 (17) | 17 (8) |