Skip to main content

Advertisement

Table 6 Effects of SAME on hepatic TBARS, GSH and DNA fragmentation of rat

From: Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats

Treatment TBARS (nM /mg protein) GSH (μM/g tissue) DNA fragmentation%
Control (Saline, 0.9% NaCl) 76.9 ± 3.0A 0.74 ± 0.02A 0.48 ± 0.08A
GTM (100 mg/kg bw) 137.4 ± 6.0D 0.48 ± 0.03D 1.34 ± 0.13D
GTM + SAME (100 mg/kg bw) 116.6 ± 5.4C 0.59 ± 0.03C 1.11 ± 0.10C
GTM + SAME (200 mg/kg bw) 104.9 ± 4.4B 0.68 ± 0.04B 0.88 ± 0.09B
SAME (200 mg/kg bw) 76.1 ± 4.1A 0.76 ± 0.03A 0.40 ± 0.08A
  1. Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other.
  2. GTM, gentamicin; SAME, methanol extract of Sonchus asper