Table 6 Effects of SAME on hepatic TBARS, GSH and DNA fragmentation of rat
From: Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats
Treatment | TBARS (nM /mg protein) | GSH (μM/g tissue) | DNA fragmentation% |
|---|---|---|---|
Control (Saline, 0.9% NaCl) | 76.9 ± 3.0A | 0.74 ± 0.02A | 0.48 ± 0.08A |
GTM (100 mg/kg bw) | 137.4 ± 6.0D | 0.48 ± 0.03D | 1.34 ± 0.13D |
GTM + SAME (100 mg/kg bw) | 116.6 ± 5.4C | 0.59 ± 0.03C | 1.11 ± 0.10C |
GTM + SAME (200 mg/kg bw) | 104.9 ± 4.4B | 0.68 ± 0.04B | 0.88 ± 0.09B |
SAME (200 mg/kg bw) | 76.1 ± 4.1A | 0.76 ± 0.03A | 0.40 ± 0.08A |