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Table 1 Effects of SAME on liver marker profile in rat

From: Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats

Treatment AST U/l ALT U/l ALP U/l LDH U/l γ-GT U/l
Control (Saline, 0.9% NaCl) 83.3 ± 9.3A 34.3 ± 4.0A 246.7 ± 16.3A 50.8 ± 6.9A 69.8 ± 6.8A
GTM (100 mg/kg bw) 182.6 ± 18.3D 68.9 ± 8.0D 366.3 ± 26.7E 64.3 ± 7.0C 94.2 ± 8.8D
GTM + SAME (100 mg/kg bw) 148.9 ± 17.6C 63.8 ± 5.6C 311.3 ± 17.8D 59.5 ± 6.2B 84.6 ± 7.6C
GTM + SAME (200 mg/kg bw) 122.1 ± 10.6B 51.0 ± 6.9B 263.7 ± 19.0C 49.0 ± 4.8A 79.5 ± 6.8BC
SAME (200 mg/kg bw) 83.5 ± 6.8A 35.6 ± 5.9A 240.7 ± 13.8A 49.7 ± 6.3A 72.6 ± 7.3A
  1. Mean ± SD (n = 06). A-D, Means not sharing common letters within a column are significantly (P < 0.01) different from each other
  2. GTM, gentamicin; SAME, methanol extract of Sonchus asper