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Table 3 Effect of the methanolic extract of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis on the activities of antioxidant enzymes and reduced glutathione content in liver of normal mice

From: Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis

   Tested Parameters
Tested Samples SOD (U/mg protein) CAT (U/mg protein) GST (U/mg protein) GSH (μg/mg protein)
Control Group I 1.28 ± 0.35 0.29 ± 0.16 0.09 ± 0.04 2.8 ± 0.7
Terminalia chebula Group II 2.33 ± 0.24*** 0.51 ± 0.22 0.11 ± 0.07 3.35 ± 0.5
  Group III 3.14 ± 0.37*** 0.74 ± 0.4 0.26 ± 0.05** 3.52 ± 0.5*
  Group IV 3.75 ± 0.27*** 1.08 ± 0.23* 0.37 ± 0.04*** 3.51 ± 0.2
Terminalia belerica Group V 2.61 ± 0.22*** 0.43 ± 0.06 0.15 ± 0.1 3.42 ± 0.3
  Group VI 3.62 ± 0.24*** 0.65 ± 0.2 0.67 ± 0.15* 4 ± 0.1
  Group VII 3.89 ± 0.15*** 0.66 ± 0.1** 0.71 ± 0.3 4.04 ± 0.12
Emblica officinalis Group VIII 2.31 ± 0.18** 0.33 ± 0.2 0.14 ± 0.2 3.04 ± 0.07
  Group IX 4.01 ± 0.17*** 1.02 ± 0.15** 0.41 ± 0.15* 3.85 ± 0.2
  Group X 4.56 ± 0.18*** 1.06 ± 0.1** 0.64 ± 0.1** 4.13 ± 0.1
  1. Group I: Control group; Groups II, III and IV represent mice treated orally with the T. chebula extract in the doses of 10, 50 and 100 mg/kg body weight, respectively; Groups V, VI and VII contain mice treated orally with the T. belerica extract in a dose of 10, 50 and 100 mg/kg body weight, respectively; Groups VIII, IX and X represent mice treated orally with the E. officinalis extract in a dose of 10, 50 and 100 mg/kg body weight, respectively. Results are expressed as mean ± SD for six mice in each group.
  2. *p < 0.05, **p < 0.01, ***p < 0.001 compared to control.