Bacillus coagulans: a viable adjunct therapy for relieving symptoms of rheumatoid arthritis according to a randomized, controlled trial

Table 2 Proportion of patients who improved in individual outcomes from baseline to 60 days

	Placebo		*Bacillus coagulans* GBI-30, 6086
	Number Improved/n	Proportion	Number Improved/n	Proportion	Difference in Proportions (95% CI)	P Value^a
Arising	3/22	0.14	4/21	0.19	-0.054 (-0.36, 0.24)	.71
Walking 2 miles	2/22	0.091	7/22	0.32	-0.23 (-0.51, 0.09)	.072
Daily activities	2/22	0.091	4/22	0.18	-0.091 (-0.38, 0.21)	.53
Dressing and grooming	4/22	0.18	4/22	0.18	0 (-0.30, 0.30)	1.0
Eating	6/22	0.27	4/22	0.18	0.09 (-0.22, 0.39)	.53
Hygiene	2/22	0.091	2/22	0.091	0 (-0.28, 0.28)	1.0
Reach	4/22	0.18	9/22	0.41	-0.23 (-0.52, 0.09)	.11
Grip	5/22	0.23	4/22	0.18	0.045 (-0.26, 0.35)	.81

^a P values calculated using Barnard's exact unconditional test to compare the proportion who improved in both groups for each individual scale.

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