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  1. Research article

    A Dalbergia odorifera extract improves the survival of endotoxemia model mice by inhibiting HMGB1 release

    Dalbergia odorifera T. Chen (Leguminosae) is an indigenous medicinal herb that is widely used as a popular remedy in northern and eastern Asia. However, the cellular mechanisms underly...

    Hyuk Soo Choi, Jin-A Park, Jung Seok Hwang, Sun Ah Ham, Taesik Yoo, Won Jin Lee, Kyung Shin Paek, Ho-Chul Shin, Chi-Ho Lee and Han Geuk Seo

    BMC Complementary and Alternative Medicine 2017 17:212

    Published on: 12 April 2017

  2. Research article

    The role of traditional healers in the diagnosis and management of Burkitt lymphoma in Cameroon: understanding the challenges and moving forward

    Burkittlymphoma(BL) is the most common childhood cancer in Cameroon with a reported incidence of 3 per 100,000 children under 15 years in the Northwest region. Treatment at three Baptist mission hospitals has ...

    Glenn M. Afungchwi, Peter B. Hesseling and Elena J. Ladas

    BMC Complementary and Alternative Medicine 2017 17:209

    Published on: 11 April 2017

  3. Research article

    Neuroprotective effect of Aronia melanocarpa extract against glutamate-induced oxidative stress in HT22 cells

    Glutamate (an endogenous excitatory neurotransmitter) at high concentrations contributes to the development of neurodegenerative diseases. Aronia melanocarpa (A. melanocarpa) berries contain anthocyanins and have...

    Hyeon Yong Lee, Jin Bae Weon, Gahee Ryu, Woo Seung Yang, Nam Young Kim, Myong Ki Kim and Choong Je Ma

    BMC Complementary and Alternative Medicine 2017 17:207

    Published on: 11 April 2017

  4. Research article

    The Chinese medicine JC-001 enhances the chemosensitivity of Lewis lung tumors to cisplatin by modulating the immune response

    JC-001 is a Chinese medicine that can modulate the immunity in Hepa 1-6 tumor-bearing mice, and we questioned whether JC-001 can serve as efficient adjuvant chemotherapy. We aimed to identify a novel approach ...

    Meng-Hsien Chuang, Ming-Shiou Jan, Jinghua Tsai Chang and Fung-Jou Lu

    BMC Complementary and Alternative Medicine 2017 17:210

    Published on: 11 April 2017

  5. Research article

    4,5,4′-Trihydroxychalcone, 8,8′-(ethene-1,2-diyl)-dinaphtalene-1,4,5-triol and rutin from Gynura segetum inhibit phagocytosis, lymphocyte proliferation, cytokine release and nitric oxide production from phagocytic cells

    Gynura segetum is used traditionally to treat various ailments related to the immune system, which include cancer, inflammation, rheumatism, diabetes, hypertension, and viral infection...

    Yuandani, Ibrahim Jantan and Khairana Husain

    BMC Complementary and Alternative Medicine 2017 17:211

    Published on: 11 April 2017

  6. Research article

    Prevalence and determinants of use of complementary and alternative medicine by hypertensive patients attending primary health care facilities in Kinshasa, Democratic Republic of the Congo: a cross-sectional study

    In the Democratic Republic of the Congo the control of hypertension is poor, characterized by an increasing number of reported cases of hypertension related complications. Poor control of hypertension is assoc...

    Aimée M. Lulebo, Mala A. Mapatano, Paulin B. Mutombo, Eric M. Mafuta, Gédéon Samba and Yves Coppieters

    BMC Complementary and Alternative Medicine 2017 17:205

    Published on: 8 April 2017

  7. Research article

    Which potential harms and benefits of using ginger in the management of nausea and vomiting of pregnancy should be addressed? a consensual study among pregnant women and gynecologists

    Nausea and vomiting of pregnancy (NVP) affect approximately 80–90% of the pregnant women. Ginger (Zingiber officinale Roscoe) is the most widely used herbal therapy in the management of NVP. Like conventional the...

    Ramzi Shawahna and Assim Taha

    BMC Complementary and Alternative Medicine 2017 17:204

    Published on: 8 April 2017

  8. Research article

    Effect of traditional Chinese medicine formula Sinisan on chronic restraint stress-induced nonalcoholic fatty liver disease: a rat study

    Nonalcoholic fatty liver disease (NAFLD) represents one of the most common forms of liver disease worldwide, and it is always regarded as a consequence of a sedentary, food-abundant lifestyle, sitting for an e...

    Fafeng Cheng, Chongyang Ma, Xueqian Wang, Changming Zhai, Guoli Wang, Xiaolin Xu, Jie Mu, Changxiang Li, Zisong Wang, Xiaoyu Zhang, Wenchao Yue, Xin Du, Yajun Lian, Wenxiang Zhu, Xiangjun Yin, Zhen Wei…

    BMC Complementary and Alternative Medicine 2017 17:203

    Published on: 7 April 2017

  9. Research article

    Enhanced efficacy with reduced toxicity of chemotherapy drug 5-fluorouracil by synergistic treatment with Abnormal Savda Munziq from Uyghur medicine

    Abnormal Savda Munziq (ASMq) is a traditional prescription in Uyghur Medicine, and its treatment of complex diseases such as tumors and asthma has been proven to be effective in Uyghur medical clinical practic...

    Tao Yang, Mutalifu Aimaiti, Deqi Su, Weiwei Miao, Bin Zhou, Dilinuer Maimaitiyiming, Abdiryim Yusup, Halmurat Upur and Ainiwaer Aikemu

    BMC Complementary and Alternative Medicine 2017 17:201

    Published on: 7 April 2017

  10. Research article

    Tea (Camellia sinensis) infusions ameliorate cancer in 4TI metastatic breast cancer model

    Tea (Camellia sinensis) infusions are widely consumed beverages with numerous health benefits. However, physiological and molecular responses mediating these activities are poorly understood.

    Karori S. Mbuthia, Paul O. Mireji, Raphael M. Ngure, Francesca Stomeo, Martina Kyallo, Chalo Muoki and Francis N. Wachira

    BMC Complementary and Alternative Medicine 2017 17:202

    Published on: 7 April 2017

  11. Research article

    Annurca apple (M. pumila Miller cv Annurca) extracts act against stress and ageing in S. cerevisiae yeast cells

    During the past years, a number of studies have demonstrated the positive effect of apple on ageing and different diseases such as cancer, degenerative and cardiovascular diseases.

    Mariarita Stirpe, Vanessa Palermo, Michele Maria Bianchi, Romano Silvestri, Claudio Falcone, Giancarlo Tenore, Ettore Novellino and Cristina Mazzoni

    BMC Complementary and Alternative Medicine 2017 17:200

    Published on: 5 April 2017

  12. Research article

    Prevalence, knowledge and attitudes toward herbal medication use by Saudi women in the central region during pregnancy, during labor and after delivery

    Herbal medication usage is prevalent in both developing and developed countries. The low level of awareness of the possible dangers of some herbs during pregnancy increases the risk of unwarranted sequelae. Th...

    Sameer Al-Ghamdi, Khaled Aldossari, Jamaan Al-Zahrani, Fawaz Al-Shaalan, Saad Al-Sharif, Hamad Al-Khurayji and Aiman Al-Swayeh

    BMC Complementary and Alternative Medicine 2017 17:196

    Published on: 4 April 2017

  13. Research article

    The Hippo signaling pathway: a potential therapeutic target is reversed by a Chinese patent drug in rats with diabetic retinopathy

    The Hippo signaling pathway is reported to be involved in angiogenesis, but the roles of the Hippo pathway in diabetic retinopathy have not been addressed. Fufang Xueshuantong Capsule has been used to treat di...

    Gai-mei Hao, Tian-tian Lv, Yan Wu, Hong-liang Wang, Wei Xing, Yong Wang, Chun Li, Zi-jian Zhang, Zheng-lin Wang, Wei Wang and Jing Han

    BMC Complementary and Alternative Medicine 2017 17:187

    Published on: 4 April 2017

  14. Research article

    Chronic low back pain patients’ use of, level of knowledge of and perceived benefits of complementary medicine: a cross-sectional study at an academic pain center

    Chronic pain patients often use complementary medicine (CM) to alleviate their pain; however, little is known about the use of CM by chronic low back pain (cLBP) patients. We investigated the frequency of use ...

    Julie Dubois, Emmanuelle Scala, Mohamed Faouzi, Isabelle Decosterd, Bernard Burnand and Pierre-Yves Rodondi

    BMC Complementary and Alternative Medicine 2017 17:193

    Published on: 4 April 2017

  15. Study protocol

    Effects of a Delphi consensus acupuncture treatment protocol on the levels of stress and vascular tone in women undergoing in-vitro fertilization: a randomized clinical trial protocol

    The variability of published acupuncture protocols for patients undergoing In-Vitro Fertilization (IVF) complicates the interpretation of data and hinders our understanding of acupuncture’s impact. In 2012, an...

    Yan Zhang, Jennifer Phy, Chris Scott-Johnson, Sheila Garos, Jennie Orlando, Samuel Prien and Jaou-Chen Huang

    BMC Complementary and Alternative Medicine 2017 17:197

    Published on: 4 April 2017

  16. Research article

    Complementary and alternative medicine use: Results from a descriptive study of pregnant women in Udi local Government area of Enugu state, Nigeria

    The use of CAM by pregnant women is very popular in developed countries. The trend is increasing globally and lack of evidence of safety particularly when used during pregnancy may lead to complications. Pregn...

    Jane-lovena Onyiapat, Chinyelu Okafor, Ijeoma Okoronkwo, Agnes Anarado, Ekene Chukwukelu, Ada Nwaneri and Pat Okpala

    BMC Complementary and Alternative Medicine 2017 17:189

    Published on: 4 April 2017

  17. Research article

    Results from a clinical yoga program for veterans: yoga via telehealth provides comparable satisfaction and health improvements to in-person yoga

    Yoga is increasingly popular, though little data regarding its implementation in healthcare settings is available. Similarly, telehealth is being utilized more frequently to increase access to healthcare; howe...

    R. Jay Schulz-Heik, Hilary Meyer, Louise Mahoney, Michael V. Stanton, Rachael H. Cho, Danae P. Moore-Downing, Timothy J. Avery, Laura C. Lazzeroni, Joanne M. Varni, Linda Martin Collery and Peter J. Bayley

    BMC Complementary and Alternative Medicine 2017 17:198

    Published on: 4 April 2017

  18. Research article

    Phytochemical analysis with free radical scavenging, nitric oxide inhibition and antiproliferative activity of Sarcocephalus pobeguinii extracts

    Free radicals have been implicated in the pathogenesis of diverse metabolic disorders including cancer. Therefore, fighting against free radicals has become an important strategy in the prevention or treatment...

    Emmanuel Mfotie Njoya, Aristide Mfifen Munvera, Pierre Mkounga, Augustin Ephrem Nkengfack and Lyndy Joy McGaw

    BMC Complementary and Alternative Medicine 2017 17:199

    Published on: 4 April 2017

  19. Research article

    Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice

    Our previous studies demonstrated that post-weaning social isolation (ISO) in mice induces behavior abnormalities such as deficits of sociability- and attention-like behaviors. These deficits can be attenuated...

    Hironori Fujiwara, Yaoyu Han, Ken Ebihara, Suresh Awale, Ryota Araki, Takeshi Yabe and Kinzo Matsumoto

    BMC Complementary and Alternative Medicine 2017 17:195

    Published on: 4 April 2017

  20. Research article

    Aqueous extract of Peperomia pellucida (L.) HBK accelerates fracture healing in Wistar rats

    Peperomia pellucida (L.) HBK is consumed as vegetable and used in Cameroonian traditional medicine for the management of diseases and for fracture healing. Therefore the aim of this st...

    Ngueguim Tsofack Florence, Sakouong Talle Suewellyne Huguette, Donfack Jean Hubert, Gounoue Kamkumo Raceline, Dzeufiet Djomeni Paul Desire, Kamtchouing Pierre and Dimo Theophile

    BMC Complementary and Alternative Medicine 2017 17:188

    Published on: 4 April 2017

  21. Research article

    Antiangiogenic effects of oridonin

    Oridonin, the major terpene found in Rabdosia rubescens (Henmsl.) Hara, is widely used as a dietary supplement and therapeutic drug. Oridonin has been proven to possess good anti-tumour activity, but little is kn...

    Lili Tian, Kangjie Xie, Donglai Sheng, Xiaoqing Wan and Guofu Zhu

    BMC Complementary and Alternative Medicine 2017 17:192

    Published on: 4 April 2017

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