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  1. Research article

    Phenolic compounds isolated from fermented blueberry juice decrease hepatocellular glucose output and enhance muscle glucose uptake in cultured murine and human cells

    We recently reported that blueberry juice fermented (FJ) with Serratia vaccinii bacterium has antidiabetic activities both in vivo and in vitro. The purpose of this project was to elucidate the effect of FJ on gl...

    Abir Nachar, Hoda M. Eid, Melinda Vinqvist-Tymchuk, Tri Vuong, Wilhelmina Kalt, Chantal Matar and Pierre S. Haddad

    BMC Complementary and Alternative Medicine 2017 17:138

    Published on: 4 March 2017

  2. Research article

    Modified lingguizhugan decoction incorporated with dietary restriction and exercise ameliorates hyperglycemia, hyperlipidemia and hypertension in a rat model of the metabolic syndrome

    Modified Lingguizhugan Decoction (MLD) came from famous Chinese medicine Linggui Zhugan Decoction. The MLD is used for the treatment of metabolic syndrome in the clinical setting. Our study focuses on the comp...

    Limei Yao, Jingjing Wei, Si Shi, Kunbin Guo, Xiangyu Wang, Qi Wang, Dingsheng Chen and Weirong Li

    BMC Complementary and Alternative Medicine 2017 17:132

    Published on: 28 February 2017

  3. Research article

    The antibacterial activity of extracts of nine plant species with good activity against Escherichia coli against five other bacteria and cytotoxicity of extracts

    The development of antibiotic resistant bacteria stems from a number of factors, including inappropriate use of antibiotics in human and animal health and their prolonged use as growth promoters at sub-clinica...

    Ishaku Leo Elisha, Francien S. Botha, Lyndy Joy McGaw and Jacobus Nicolaas Eloff

    BMC Complementary and Alternative Medicine 2017 17:133

    Published on: 28 February 2017

  4. Research article

    Anti-mycobacteria potential and synergistic effects of combined crude extracts of selected medicinal plants used by Bapedi traditional healers to treat tuberculosis related symptoms in Limpopo Province, South Africa

    Tuberculosis is an infectious communicable disease and the causative agent of the disease has over the years developed resistance to streamline chemotherapeutic agents with dire consequences and there is a nee...

    Nancy Patience Motlalepula Komape, Victor Patrick Bagla, Prudence Kabongo-Kayoka and Peter Masoko

    BMC Complementary and Alternative Medicine 2017 17:128

    Published on: 24 February 2017

  5. Research article

    The herbal formula KH-204 is protective against erectile dysfunction by minimizing oxidative stress and improving lipid profiles in a rat model of erectile dysfunction induced by hypercholesterolaemia

    Hypercholesterolaemia (HC) is a major risk factor for ischemic heart disease and is also known to be a risk factor for erectile dysfunction (ED). ED caused by HC is thought to be related to HC-induced oxidativ...

    Hoon Jang, Woong Jin Bae, Su Jin Kim, Hyuk Jin Cho, Seung Mo Yuk, Dong Seok Han, Chang Shik Youn, Eun Bi Kwon, Sung Yeoun Hwang and Sae Woong Kim

    BMC Complementary and Alternative Medicine 2017 17:129

    Published on: 24 February 2017

  6. Research article

    The Chinese prescription lianhuaqingwen capsule exerts anti-influenza activity through the inhibition of viral propagation and impacts immune function

    Lianhuaqingwen Capsule (LH-C) is a traditional Chinese medicine (TCM) formula used to treat respiratory tract infectious diseases in Chinese. The aim of this study was to determine the antiviral activity of LH...

    Yuewen Ding, Lijuan Zeng, Runfeng Li, Qiaoyan Chen, Beixian Zhou, Qiaolian Chen, Pui leng Cheng, Wang Yutao, Jingping Zheng, Zifeng Yang and Fengxue Zhang

    BMC Complementary and Alternative Medicine 2017 17:130

    Published on: 24 February 2017

  7. Research article

    Allium hookeri root extract exerts anti-inflammatory effects by nuclear factor-κB down-regulation in lipopolysaccharide-induced RAW264.7 cells

    Allium hookeri (AH) is widely consumed as a vegetable and herbal medicine in southeastern Asia. AH has been reported antioxidant, antimicrobial, improvement of bone health and antidiab...

    Ja-Young Jang, Min-Jung Lee, Bo-Ram You, Jong-Sik Jin, Sung-Hyen Lee, Ye-Rang Yun and Hyun Ju Kim

    BMC Complementary and Alternative Medicine 2017 17:126

    Published on: 23 February 2017

  8. Research article

    Chemical composition and pharmacological significance of Anethum Sowa L. Root

    Medicinal herbs are used for the treatment of different ailments since antiquity. Different parts of Anethum sowa L. is used in folk medicine as a carminative for the treatment of flatulence, colic and hiccups of...

    Md Moshfekus Saleh-e-In, Nasim Sultana, Md Matiur Rahim, Md Aminul Ahsan, Md Nurul Huda Bhuiyan, Md Nur Hossain, Md Mahbubar Rahman, Sudhangshu Kumar Roy and Md Rabiul Islam

    BMC Complementary and Alternative Medicine 2017 17:127

    Published on: 23 February 2017

  9. Research article

    Effects of mindfulness-based interventions on biomarkers in healthy and cancer populations: a systematic review

    Only a small number of articles have investigated the relationship between mindfulness-based interventions (MBIs) and biomarkers. The aim of this systematic review was to study the effect of MBIs on specific b...

    Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María C. Pérez-Yus, Marcelo M. P. Demarzo, Jesús Montero-Marín, Mauro García-Toro and Javier García-Campayo

    BMC Complementary and Alternative Medicine 2017 17:125

    Published on: 23 February 2017

  10. Research article

    Chemical composition and anti-herpes simplex virus type 1 (HSV-1) activity of extracts from Cornus canadensis

    Many plants of boreal forest of Quebec have been used by Native Americans to treat a variety of microbial infections. However, the antiviral activities of these plants have been seldom evaluated on cellular mo...

    Serge Lavoie, Isabelle Côté, André Pichette, Charles Gauthier, Michaël Ouellet, Francine Nagau-Lavoie, Vakhtang Mshvildadze and Jean Legault

    BMC Complementary and Alternative Medicine 2017 17:123

    Published on: 22 February 2017

  11. Research article

    Anti-obesity effect of ethanolic extract from Cosmos caudatus Kunth leaf in lean rats fed a high fat diet

    Obesity is a major health concern both in developed and developing countries. The use of herbal medicines became the subject of interest for the management of obesity due to its natural origin, cost effectiven...

    Hafeedza Abdul Rahman, Najla Gooda Sahib, Nazamid Saari, Faridah Abas, Amin Ismail, Muhammad Waseem Mumtaz and Azizah Abdul Hamid

    BMC Complementary and Alternative Medicine 2017 17:122

    Published on: 22 February 2017

  12. Research article

    Exploration of anti-cancer effects and mechanisms of Zuo-Jin-Wan and its alkaloid components in vitro and in orthotopic HepG2 xenograft immunocompetent mice

    Zuo-Jin-Wan (ZJW), a two-herb formula consisting of Coptis chinensis (CC) and Evodia rutaecarpa (ER), is commonly used in traditional Chinese medicine for the treatment of cancers. However, the efficacies and mec...

    Shun-Ting Chou, Chien-Yun Hsiang, Hsin-Yi Lo, Hui-Fen Huang, Ming-Tsung Lai, Ching-Liang Hsieh, Su-Yin Chiang and Tin-Yun Ho

    BMC Complementary and Alternative Medicine 2017 17:121

    Published on: 20 February 2017

  13. Research article

    Bacopa monnieri extract increases rat coronary flow and protects against myocardial ischemia/reperfusion injury

    This study explored Bacopa monnieri, a medicinal Ayurvedic herb, as a cardioprotectant against ischemia/reperfusion injury using cardiac function and coronary flow as end-points.

    Sirintorn Srimachai, Sylvie Devaux, Celine Demougeot, Sarawut Kumphune, Nina D. Ullrich, Ernst Niggli, Kornkanok Ingkaninan, Natakorn Kamkaew, C. Norman Scholfield, Sompol Tapechum and Krongkarn Chootip

    BMC Complementary and Alternative Medicine 2017 17:117

    Published on: 20 February 2017

  14. Research article

    Prescription frequency and patterns of Chinese herbal medicine for liver cancer patients in Taiwan: a cross-sectional analysis of the National Health Insurance Research Database

    Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Chinese herbal medicine (CHM) is frequently provided to HCC patients. The aim of this study was to understand the p...

    Chin-Tsung Ting, Chian-Jue Kuo, Hsiao-Yun Hu, Ya-Ling Lee and Tung-Hu Tsai

    BMC Complementary and Alternative Medicine 2017 17:118

    Published on: 20 February 2017

  15. Research article

    Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NFκB and ERK pathways in Raw 264.7 cells

    Activation of macrophage is involved in many inflammation diseases. Lipopolysaccharide (LPS) is a powerful inflammatory signal contributing to monocytes/macrophages activation associated with increased proinfl...

    Haijian Sun, Weiwei Cai, Xu Wang, Yanling Liu, Bao Hou, Xuexue Zhu and Liying Qiu

    BMC Complementary and Alternative Medicine 2017 17:120

    Published on: 20 February 2017

  16. Research article

    An interpretive review of consensus statements on clinical guideline development and their application in the field of traditional and complementary medicine

    Despite ongoing consumer demand and an emerging scientific evidence-base for traditional and complementary medicine (T&CM), there remains a paucity of reliable information in standard clinical guidelines about...

    Jennifer Hunter, Matthew Leach, Lesley Braun and Alan Bensoussan

    BMC Complementary and Alternative Medicine 2017 17:116

    Published on: 17 February 2017

  17. Research article

    UP601, a standardized botanical composition composed of Morus alba, Yerba mate and Magnolia officinalis for weight loss

    The prevalence of obesity is surging in an alarming rate all over the world. Pharmaceutical drugs are considered potential adjunctive therapy to lifestyle modification. However, for most, besides being too exp...

    Mesfin Yimam, Ping Jiao, Mei Hong, Lidia Brownell, Young-Chul Lee, Eu-Jin Hyun, Hyun-Jin Kim, Jeong-Bum Nam, Mi-Ran Kim and Qi Jia

    BMC Complementary and Alternative Medicine 2017 17:114

    Published on: 16 February 2017

  18. Research article

    Use of ethanol extracts of Terminalia chebula to prevent periodontal disease induced by dental plaque bacteria

    The fruit of the Terminalia chebula tree has been widely used for the treatment of various disorders. Its anti-diabetic, anti-mutagenic, anti-oxidant, anti-bacterial, anti-fungal, and anti-viral effects have been...

    Jongsung Lee, Youn Hwa Nho, Seok Kyun Yun and Young Sun Hwang

    BMC Complementary and Alternative Medicine 2017 17:113

    Published on: 16 February 2017

  19. Research article

    BreastDefend enhances effect of tamoxifen in estrogen receptor-positive human breast cancer in vitro and in vivo

    Tamoxifen (TAM) has been widely used for the treatment of estrogen receptor (ER)-positive breast cancer and its combination with other therapies is being actively investigated as a way to increase efficacy and...

    Shujie Cheng, Victor Castillo, Matt Welty, Mark Alvarado, Isaac Eliaz, Constance J. Temm, George E. Sandusky and Daniel Sliva

    BMC Complementary and Alternative Medicine 2017 17:115

    Published on: 16 February 2017

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