Fig. 2
From: Ginsenoside compound K induces ferroptosis via the FOXO pathway in liver cancer cells
CK induced ferroptosis of HCC cells HepG2 and SK-Hep-1. (A) FerroOrange probe was used to detect Fe2+ levels in HepG2 and SK-Hep-1 cells (400×). (B) The intracellular lipid peroxidation rate of HepG2 and SK-Hep-1 cells (400×). (C, D) The GSH and MDA contents in HepG2 and SK-Hep-1 cells were detected. (E, F) Expression of ferroptosis-related proteins GPX4 and SLC7A11. *P < 0.05, **P < 0.01, ***P < 0.001, compared with the vehicle group. Pairwise comparison between groups was performed by t-test