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Table 1 The alleviative role of RUT against VORTX toxicity on organ and body weight

From: The ameliorating effect of Rutin on hepatotoxicity and inflammation induced by the daily administration of vortioxetine in rats

Groups

Body weight (g) Mean ± SE

Liver weight

(g)

Initial

Final

Control Rats (G1)

158.333 ± 3.158$

268.833 ± 7.586@

1.921 ± 0.020@

Rats exposed to RUT (G2)

158.167 ± 2.257$

264.833 ± 5.594@

1.935 ± 0.020@

Rats exposed to VORTX low dose (G3)

160 ± 4.049$

200.833 ± 3.360$

1.656 ± 0.054#

Rats exposed to VORTX low dose + RUT (G4)

160.5 ± 5.981$

240.666 ± 3.480#

1.755 ± 0.045@

Rats exposed to VORTX high dose (G5)

165.5 ± 6.026$

187.166 + 1.301$

1.186 ± 0.052#

Rats exposed to VORTX high dose + RUT (G6)

164.666 ± 5.713$

199 ± 3.651$

1.41 ± 0.051#

  1. Values are expressed as mean ± SE of 6 rats per group. Values with the same superscript symbols are non-significant at (P>0.05) RUT = Rutin, Vortioxetine = VORTX