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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Huang Lian Jie Du Decoction enhances the anti-tumor efficacy of immune checkpoint inhibitors by activating TLR7/8 signalling in melanoma

Fig. 5

HLJD treatment upregulated Type I IFN signaling. (A, B and C) Volcano Plot graph and Bar graphs of PCR-array of TLR7/8 and Type I IFN signaling axis. (D) The expression of IRF7 was determined by qRT-PCR. (E) IFN-α quantification by ELISA in tumor tissue. Statistical differences were determined using the student’s t-test. (*p < 0.05, **p < 0.01) HLJD = Huang Lian Jie Du Decoction, ICIs = anti-PD-1 + anti-CTLA-4

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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