Table 4 The cytotoxic effect of C. arvensis, C. arvensis-alginate/chitosan-NPs, alginate/chitosan- NPs and standard (Doxorubicin) on the Vero cell lines

1000

61.97 ± 1.40

60.40 ± 1.23

67.23 ± 1.23

68.09 ± 1.58

69.23 ± 1.41

14.25 ± 0.62

500

64.39 ± 1. 23

64.82 ± 0.88

70.37 ± 1.92

72.22 ± 1.26

72.08 ± 1.65

25.09 ± 0.57

250

69.09 ± 1.92

70.94 ± 1.75

78.63 ± 1.74

77.94 ± 1.95

78.07 ± 1.22

29.99 ± 0.41

125

74.22 ± 1.56

73.79 ± 1.41

81.05 ± 1.98

80.34 ± 1. 39

81.91 ± 1.06

34.59 ± 0.79

62.5

77.35 ± 1.40

77.21 ± 1.01

84.62 ± 1.45

83.62 ± 1. 76

86.47 ± 1.57

41.96 ± 0.87

31.25

80.91 ± 0.88

79.50 ± 1.59

91.17 ± 1.41

90.31 ± 1.41

92.16 ± 1.75

44.09 ± 1.55

15.56

86.89 ± 1.41

86.04 ± 1.41

96.01 ± 1.23

95.44 ± 1.41

94.73 ± 2.32

57.73 ± 0.94

IC₅₀ (µg/ml)

22.09