Table 2 Anti-inflammatory activity of C. arvensis, C. arvensis-alginate/chitosan-NPs, alginate/chitosan-NPs and standard (Diclofenac sodium)

1000

49.11 ± 1.09

49.71 ± 0.88

61.98 ± 2.02

62.38 ± 2.14

54.93 ± 0.74

69.96 ± 1.46

500

44.01 ± 1.41

43.81 ± 1.71

54.98 ± 1.59

55.61 ± 1.73

51.07 ± 0.89

57.49 ± 1.02

250

38.42 ± 0.77

39.12 ± 0.84

49.95 ± 0.89

50.75 ± 1.09

46.08 ± 1.22

52.89 ± 1.51

125

27.83 ± 1.05

28.13 ± 1.15

44.99 ± 0.84

45.19 ± 0.65

41.69 ± 0.57

47.06 ± 0.69

62.5

22.16 ± 0.78

21.96 ± 0.73

39.06 ± 0.68

38.46 ± 0.61

33.16 ± 0.49

40.17 ± 1.18

31.25

16.69 ± 0.71

16.92 ± 0.78

22.19 ± 1.29

22.99 ± 1.11

16.85 ± 0.42

26.42 ± 0.51

15.56

11.88 ± 0.79

12.18 ± 0.74

18.94 ± 0.480

17.99 ± 0.42

13.97 ± 0.41

19.97 ± 0.78

IC₅₀ (µg/ml)

1050

1050

175

175

555

143