Fig. 5
The impact of G. lucidum-fermented crop extracts on antioxidant enzyme depletion in SH-SY5Y cells was evaluated under two conditions: (A) H2O2- and (B) Aβ25-35-induced oxidative stress. The cells were pretreated with either GABA standard or various G. lucidum extracts for 6 h, followed by exposure to H2O2 (150 μM) or Aβ25-35 (10 μM) for 6 h (GPx and CAT) or 12 h (SOD) to measure the activity of antioxidant enzymes, as described in the Materials and methods section. The data were presented as mean ± SD from three independent experiments. Different letters (a-f) displayed within the same figure indicate significant differences (p < 0.05) among the various treatment groups