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Fig. 3 | BMC Complementary Medicine and Therapies

Fig. 3

From: Panax notoginseng saponins prevent dementia and oxidative stress in brains of SAMP8 mice by enhancing mitophagy

Fig. 3

Panax notoginseng saponins enhance the level of autophagy in hippocampi of SAMP8 demented mice. A Red arrows show transmission electron micrographs of damaged mitochondria, yellow arrows show autophagosomes and blue arrows show autophagosomes containing damaged mitochondria. B-C LC3 mRNA and P62 mRNA expression in mouse hippocampus, n = 9. D Western blot of autophagy-related protein LC3 in the mouse hippocampus. E LC3-II/I protein ratio in mouse hippocampus, n = 5; aP < 0.05, bP < 0.01 compared with the control group, cP < 0.05, dP < 0.01 compared with the model group

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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