Table 2 Antiviral activity of substances isolated from P. chinense against influenza viruses in the CPE reduction assay
Sample | Identity | CC50 a | EC50 b (S.I.c) | Unit | ||
|---|---|---|---|---|---|---|
PR8d | HKe | Leef | ||||
PC1 | quercetin | > 300.0 | 12.6 (> 23.8) | 13.1 (> 22.9) | 15.0 (> 20.0) | μg/mL |
PC2 | protocatechuic acid methyl ester | 24.1 | > 24.1 (N.A.g) | > 24.1 (N.A.) | 11.1 (2.2) | μg/mL |
PC3 | gallic acid | 111.1 | 20.8 (5.3) | 17.5 (6.3) | 24.5 (4.5) | μg/mL |
PC5 | ellagic acid | > 300.0 | 81.1 (> 3.7) | 62.4 (> 4.8) | 79.2 (> 3.8) | μg/mL |
PC6 | β-sitosterol | 300.0 | 281.6 (1.1) | 300.0 (1.0) | > 300.0 (N.A.) | μg/mL |
PC7 | methyl gallate | > 300.0 | 18.1 (> 16.6) | 17.1 (> 17.5) | 19.2 (> 15.6) | μg/mL |
PC8 | caffeic acid | > 300.0 | 37.8 (> 7.9) | 32.1 (> 9.4) | 14.7 (> 20.4) | μg/mL |
RBVh | - | > 100.0 | 21.7 (> 4.6) | 15.5 (> 6.5) | 17.0 (> 5.9) | μM |
OSV-Ci | - | > 100.0 | 0.07 (> 1428) | < 0.005 (> 20,000) | 0.21 (> 476) | μM |