Age groups (year-old) | Non-TCM user | TCM user | IRR (95Â % CI) | Adjusted HRb | ||||
---|---|---|---|---|---|---|---|---|
Disease (ICD-9-CM) | N (%) | Person-years | IRa | N (%) | Person-years | IRa | (95Â % CI) | |
Hepatitis B (70.2, 070.3, V02.61) | ||||||||
 All | 570(19.82) | 13085 | 43.56 | 1356(23.83) | 39350 | 34.46 | 0.79(0.72−0.87)*** | 0.55(0.46−0.66)*** |
 18−39 | 88(24.18) | 1901 | 46.3 | 239(25.29) | 7189 | 33.24 | 0.72(0.56−0.92)** | 0.41(0.25−0.69)*** |
 40−64 | 327(22.54) | 6923 | 47.23 | 842(24.80) | 23900 | 35.23 | 0.75(0.66−0.85)*** | 0.48(0.37−0.6)*** |
  ≥ 65 | 155(14.61) | 4261 | 36.37 | 275(20.36) | 8260 | 33.29 | 0.92(0.75−1.11) | 0.82(0.58−1.17) |
Liver cirrhosis (571.2, 571.5, 571.6, 572.2, 572.3, 572.4, 572.8, 573.0) | ||||||||
 All | 989(34.39) | 13085 | 75.58 | 1618(28.43) | 39350 | 41.12 | 0.54(0.50−0.59)*** | 0.42(0.37−0.48)*** |
 18−39 | 45(12.36) | 1901 | 23.68 | 108(11.43) | 7189 | 15.02 | 0.63(0.45−0.90)* | 0.43(0.25−0.73)** |
 40−64 | 489(33.70) | 6923 | 70.63 | 951(28.01) | 23900 | 39.79 | 0.56(0.51−0.63)*** | 0.39(0.33−0.46)*** |
  ≥ 65 | 455(42.88) | 4261 | 106.77 | 559(41.38) | 8260 | 67.67 | 0.63(0.56−0.72)*** | 0.54(0.44−0.66)*** |
hepatocellular carcinoma (155) | ||||||||
 All | 535(18.60) | 13085 | 40.89 | 898(15.78) | 39350 | 22.82 | 0.56(0.50−0.62)*** | 0.78(0.45−1.36) |
 18−39 | 6(1.65) | 1901 | 3.16 | 33(3.49) | 7189 | 4.59 | 1.45(0.61−3.47) | 1.25(0.12−12.75) |
 40−64 | 242(16.68) | 6923 | 34.96 | 514(15.14) | 23900 | 21.51 | 0.62(0.53−0.72)*** | 0.98(0.43−2.21) |
  ≥ 65 | 287(27.05) | 4261 | 67.35 | 351(25.98) | 8260 | 42.49 | 0.63(0.54−0.74)*** | 0.72(0.29−1.75) |
Alcohol-related disease (291, 303.0, 303.9, 305.0, 571.0, 571.1, 571.3) | ||||||||
 All | 294(10.22) | 13085 | 22.47 | 477(8.38) | 39350 | 12.12 | 0.54(0.47−0.62)*** | 0.41(0.32−0.51)*** |
 18−39 | 65(17.86) | 1901 | 34.2 | 124(13.12) | 7189 | 17.25 | 0.50(0.37−0.68)*** | 0.37(0.24−0.58)*** |
 40−64 | 185(12.75) | 6923 | 26.72 | 290(8.54) | 23900 | 12.13 | 0.45(0.38−0.55)*** | 0.31(0.23−0.42)*** |
  ≥ 65 | 44(4.15) | 4261 | 10.33 | 63(4.66) | 8260 | 7.63 | 0.74(0.50−1.09) | 0.61(0.33−1.16) |
Chronic obstructive pulmonary disease (491, 492) | ||||||||
 All | 508(17.66) | 13085 | 38.82 | 1402(24.64) | 39350 | 35.63 | 0.92(0.83−1.12) | 0.59(0.50−0.70)*** |
 18−39 | 27(7.42) | 1901 | 14.21 | 120(12.70) | 7189 | 16.69 | 1.18(0.77−1.78) | 0.94(0.45−1.97) |
 40−64 | 198(13.65) | 6923 | 28.6 | 786(23.15) | 23900 | 32.89 | 1.15(0.98−1.34) | 0.67(0.52−0.86)** |
  ≥ 65 | 283(26.67) | 4261 | 66.41 | 496(36.71) | 8260 | 60.05 | 0.90(0.78−1.05) | 0.69(0.53−0.89)** |
Diabetes Mellitus (250) | ||||||||
 All | 1046(36.37) | 13085 | 79.94 | 2143(37.66) | 39350 | 54.46 | 0.68(0.63−0.73)*** | 0.48(0.42−0.55)*** |
 18−39 | 55(15.11) | 1901 | 28.94 | 151(15.98) | 7189 | 21 | 0.73(0.53−0.99)* | 0.40(0.22−0.71)** |
 40−64 | 572(39.42) | 6923 | 82.62 | 1358(40.00) | 23900 | 56.82 | 0.69(0.62−0.76)*** | 0.46(0.38−0.54)*** |
  ≥ 65 | 419(39.49) | 4261 | 98.32 | 634(46.93) | 8260 | 76.75 | 0.78(0.69−0.88)*** | 0.64(0.51−0.8)*** |
Thyroid disease (240, 241, 242, 244) | ||||||||
 All | 145(5.04) | 13085 | 11.08 | 631(11.09) | 39350 | 16.04 | 1.44(1.21−1.73)*** | 0.90(0.67−1.21) |
 18−39 | 21(5.77) | 1901 | 11.05 | 105(11.11) | 7189 | 14.6 | 1.32(0.83−2.11) | 1.33(0.54−3.28) |
 40−64 | 79(5.44) | 6923 | 11.41 | 418(12.31) | 23900 | 17.49 | 1.53(1.21−1.95)*** | 0.9(0.6−1.36) |
  ≥ 65 | 45(4.24) | 4261 | 10.56 | 108(7.99) | 8260 | 13.07 | 1.24(0.87−1.75) | 0.92(0.53−1.58) |
Rheumatoid arthritis (714) | ||||||||
 All | 89(3.09) | 13085 | 6.8 | 400(7.03) | 39350 | 10.17 | 1.49(1.19−1.88)*** | 1.18(0.82−1.69) |
 18−39 | 11(3.02) | 1901 | 5.79 | 42(4.44) | 7189 | 5.84 | 1.01(0.52−1.96) | 0.88(0.28−2.78) |
 40−64 | 45(3.10) | 6923 | 6.5 | 266(7.84) | 23900 | 11.13 | 1.71(1.25−2.35)*** | 1.38(0.81−2.36) |
  ≥ 65 | 33(3.11) | 4261 | 7.74 | 92(6.81) | 8260 | 11.14 | 1.44(0.97−2.14) | 1.24(0.69−2.22) |
Osteoarthritis (715) | ||||||||
 All | 953(33.14) | 13085 | 72.83 | 2922(51.34) | 39350 | 74.26 | 1.02(0.95−1.10) | 0.75(0.66−0.86)*** |
 18−39 | 46(12.64) | 1901 | 24.2 | 215(22.75) | 7189 | 29.91 | 1.24(0.90−1.70) | 1.2(0.64−2.27) |
 40−64 | 427(29.43) | 6923 | 61.68 | 1777(52.34) | 23900 | 74.35 | 1.21(1.08−1.34)*** | 0.85(0.71−1.03) |
  ≥ 65 | 480(45.24) | 4261 | 112.64 | 930(68.84) | 8260 | 112.59 | 1.00(0.90−1.12) | 0.82(0.67−1) |
Depression (296.2, 296.3, 296.5, 296.6, 305.8, 311, v790, 290.13) | ||||||||
 All | 174(6.05) | 13085 | 13.3 | 650(11.42) | 39350 | 16.52 | 1.24(1.05−1.47)* | 0.78(0.61−1.01) |
 18−39 | 31(8.52) | 1901 | 16.31 | 128(13.54) | 7189 | 17.8 | 1.09(0.74−1.62) | 0.76(0.42−1.38) |
 40−64 | 86(5.93) | 6923 | 12.42 | 382(11.25) | 23900 | 15.98 | 1.29(1.02−1.63)* | 0.73(0.52−1.04) |
  ≥ 65 | 57(5.37) | 4261 | 13.38 | 140(10.36) | 8260 | 16.95 | 1.27(0.93−1.72) | 0.89(0.54−1.48) |
Sicca syndrome (370.33, 710.2) | ||||||||
 All | 78(2.71) | 13085 | 5.96 | 423(7.43) | 39350 | 10.75 | 1.80(1.42−2.30)*** | 1.27(0.86−1.89) |
 18−39 | 4(1.10) | 1901 | 2.1 | 42(4.44) | 7189 | 5.84 | 2.78(1.00−7.74) | - |
 40−64 | 40(2.76) | 6923 | 5.78 | 266(7.84) | 23900 | 11.13 | 1.93(1.38−2.69)*** | 1.14(0.67−1.94) |
  ≥ 65 | 34(3.20) | 4261 | 7.98 | 115(8.51) | 8260 | 13.92 | 1.75(1.19−2.56)** | 1.71(0.93−3.15) |