Time | Parameters | ||||||||
---|---|---|---|---|---|---|---|---|---|
HR | MAP | LVSP | LVEDP | +dP/dtmax | -dP/dtmix | CBF | MBF | CVR | |
bpm | mmHg | mmHg | mmHg | mmHg/s | mmHg/s | ml/min | ml/min.100Â g | mmHg.min/mL | |
Pre-Occ | |||||||||
 Sham | 175.35 ± 31.3 | 119.18 ± 14.43 | 147.27 ± 23.14 | 4.89 ± 3.36 | 3050.63 ± 542.34 | −2610.66 ± 670.12 | 45.19 ± 2.41 | 161.31 ± 32.34 | 0.74 ± 0.09 |
 Model | 170.03 ± 35.3 | 123.88 ± 14.1 | 149.15 ± 13.74 | 3.45 ± 8.2 | 2850.71 ± 600.93 | −2587.09 ± 477.81 | 47.86 ± 8.87 | 182.79 ± 60.94 | 0.79 ± 0.23 |
 SX-H | 167.88 ± 23.46 | 106.99 ± 21.01 | 135.26 ± 26.29 | 4.6 ± 4.2 | 2987.07 ± 825.57 | −2329.83 ± 731.73 | 45.89 ± 7.32 | 163.02 ± 32.79 | 0.78 ± 0.21 |
 SX-M | 171.5 ± 25.06 | 106.92 ± 15.12 | 139.34 ± 7.64 | 3.68 ± 3.33 | 2764.46 ± 355 | −2426.34 ± 459.77 | 44.05 ± 6.15 | 172.57 ± 43.87 | 0.76 ± 0.24 |
 SX-L | 167.4 ± 24.96 | 113.47 ± 16.49 | 136.85 ± 17.57 | 5.1 ± 2.21 | 2785.09 ± 635.7 | −2533.04 ± 765.36 | 46.07 ± 13.52 | 145.87 ± 50.5 | 0.82 ± 0.25 |
 ISD | 171.16 ± 18.55 | 118.1 ± 20.7 | 146.88 ± 24.73 | 4.94 ± 1.9 | 2797.02 ± 481.73 | −2328 ± 542.84 | 46.84 ± 2.81 | 185.2 ± 50.47 | 0.72 ± 0.18 |
Pre-Adm | |||||||||
 Sham | 175.97 ± 27.68 | 121.45 ± 16.64 | 149.37 ± 25.47 | 5.15 ± 0.53 | 3222.04 ± 595.88 | −2720.74 ± 912.21 | 49.28 ± 7.95 | 171.94 ± 12.13 | 0.71 ± 0.09 |
 Model | 163.34 ± 33.96 | 104.26 ± 1.6 | 134.8 ± 10.66 | 7.69 ± 3.1 | 2445.67 ± 343.97 | −2416.3 ± 310.43 | 44.64 ± 10.78 | 179.61 ± 55.94 | 0.74 ± 0.19 |
 SX-H | 160.02 ± 23.66 | 97.23 ± 18.85 | 131.07 ± 22.75 | 7.74 ± 3.25 | 2234.54 ± 642.44 | −2110.49 ± 636.37 | 40.79 ± 8.1 | 149.81 ± 28.52 | 0.67 ± 0.19 |
 SX-M | 172.79 ± 26.4 | 102.51 ± 19.92 | 133.58 ± 9.97 | 6.81 ± 2.39 | 2549.35 ± 364.23 | −2373.87 ± 334.64 | 44.68 ± 10.48 | 174.87 ± 58.35 | 0.65 ± 0.22 |
 SX-L | 165.27 ± 23.43 | 103.91 ± 15.53 | 125.56 ± 14.96 | 8.1 ± 3.1 | 2437.5 ± 482.9 | −2308.27 ± 542.33 | 44.02 ± 12.37 | 137.31 ± 34.7 | 0.75 ± 0.18 |
 ISD | 165.43 ± 20.48 | 101.5 ± 23.81 | 112.53 ± 11.88 | 8.91 ± 1.35 | 2235.42 ± 509.53 | −2037.27 ± 511.09 | 46.67 ± 10.35 | 175.73 ± 77.42 | 0.70 ± 0.16 |
Post-Adm | |||||||||
 Sham | 176.98 ± 33.58 | 111.3 ± 18.19 | 133.38 ± 18.78 | 4.7 ± 2.6 | 2830.94 ± 814 | −2595.17 ± 718.67 | 50.37 ± 10.36 | 174.92 ± 18.42 | 0.68 ± 0.1 |
 Model | 168.9 ± 38.59 | 95.3 ± 12.26 | 132.34 ± 9.95 | 8.94 ± 1.87 | 1873.17 ± 532.67 | −2120.28 ± 544.01 | 33.15 ± 9.75& | 126.63 ± 27.83& | 0.82 ± 0.19& |
 SX-H | 184.27 ± 37.12 | 80.96 ± 5.29* | 96.57 ± 12.05**&& | 5.82 ± 2.65*& | 1835.97 ± 141.59 | −1862.88 ± 265.58 | 58.86 ± 13.3**& | 219 ± 64.55*&& | 0.36 ± 0.09**&& |
 SX-M | 186.38 ± 36.32 | 90.9 ± 16.36 | 97.23 ± 22.2**&& | 5.5 ± 3.05* | 1946.72 ± 380.59 | −1939.73 ± 720.86 | 49.66 ± 8.29* | 205.25 ± 74.85*&& | 0.48 ± 0.21*& |
 SX-L | 174.25 ± 20.49 | 96.5 ± 17.19 | 109.33 ± 14.06** | 6.09 ± 3.2* | 2183.55 ± 423.96 | −2081.71 ± 441.56 | 52.13 ± 13.41* | 180.23 ± 53.75*& | 0.55 ± 0.31& |
 ISD | 167.28 ± 22.23 | 82.03 ± 2.51* | 113.51 ± 6.79** | 6.41 ± 3.19*& | 2008.15 ± 175.04 | −2024.36 ± 265.35 | 61 ± 13.55**& | 222.55 ± 93.78*&& | 0.4 ± 0.15**&& |