Isolated chemicals | Evidence for effects |
---|---|
Phytoestrogens | Hormonal effects in ovarian granulosa cells [107]. |
Berberine | Comparison with metformin in PCOS [16]; ovarian theca cell hormone production [108]. |
Catechin derived from Camellia sinensis | Effects of epigallocatechin gallate 1 on cellular metabolic endocrinology [72]. |
Sapponins derived from Tribulus terrestris | Effects on reproductive endocrinology [109]. |
Paeoniflorin, glycyrrhizin and glycyrrhetic acid | Ovarian androgen production [110]. |
Isoflavones isolated from Vitex agnus-castus | Selective oestrogen receptor activity (competitive inhibition via beta oestrogen receptors) [36]. |