Figure 3From: Tanshinone IIA pretreatment protects free flaps against hypoxic injury by upregulating stem cell-related biomarkers in epithelial skin cells Epidermal cells showed upregulated Wnt signaling and enhanced stemness after pretreatment with TSA. qRT-PCR showed upregulation of β-catenin, SOX2, Nanog, OCT4, and VEGF and downregulation of GSK-3β in TSA-pretreated epithelial cells compared with control cells (A). Similar results were obtained using western blot analysis (B).Back to article page