Figure 2
From: Antineuropathic effect of 7-hydroxy-3,4-dihydrocadalin in streptozotocin-induced diabetic rodents
Flinching behavior induced by subcutaneous (s.c.) injection of 0.5% formalin to non-diabetic and diabetic rats. Time courses (A) and bar plots show formalin-induced hyperalgesic effect during phase 1 (B) and phase 2 (C) in diabetic rats administered with 60 mg/kg (i.p.) of streptozotocin 3 weeks before. Data are expressed as the mean ± E.E.M. of seven animals per group. *Significantly different (P < 0.05) from non-diabetic group, as determined by Student’s test. AUC: area under the curve.