From: Effects of Ginkgo biloba on chemically-induced mammary tumors in rats receiving tamoxifen
Experimental groups3 | ||||
---|---|---|---|---|
Parameters2 | (G1)TAM | (G2) TAM + GbE50 | (G3) TAM + GbE100 | (G4) Untreated control |
General parameters | ||||
Animal number (n) | 10/94 | 10/7 | 10/7 | 10/5 |
Tumor number (n) | 115 | 9 | 9 | 7 |
Initial body weight (g) | 267.67 ± 3.25 | 257.25 ± 4.89 | 261.80 ± 7.89 | 283.0 ± 2.83 |
Final body weight (g) | 291.33 ± 4.18 | 287.17 ± 7.99 | 287.17 ± 4.40 | 293.40 ± 3.71 |
Body weight gain (g) | 23.43 ± 5.46 | 31.17 ± 4.71 | 28.80 ± 9.75 | 20.0 ± 7.93 |
Liver relative weight (g) | 5.13 ± 0.57 | 4.38 ± 0.46 | 4.15 ± 0.67 | 4.53 ± 0.24 |
Left ovarian relative weight (mg) | 20.0 ± 6.0 | 17.0 ± 2.64 | 13.01 ± 2.64 | 19.0 ± 3.12 |
Right ovarian relative weight (mg) | 19.0 ± 5.0 | 13.0 ± 3.01 | 19.01 ± 5.56 | 17.0 ± 1.78 |
Initial tumor volume (cm3) | 2.23 ± 0.49 | 2.64 ± 0.93 | 1.95 ± 0.46 | 2.09 ± 0.82 |
Final tumor volume (cm3) | 0.85 ± 0.41* | 0.83 ± 0.47* | 0.57 ± 0.12* | 4.73 ± 1.45 |
Biochemical dosage | ||||
ALT (u/l) | 37.17 ± 3.59 | 47.83 ± 4.24 | 47.0 ± 5.47 | 35.75 ± 7.68 |
E2 (ρg/ml) | 57.80 ± 4.42 | 42.83 ± 3.24 | 34.0 ± 6.34 | 38.0 ± 6.65 |