Figure 3
Visualization of key residues involved in gB-gH-gL complex formation. A) Amino acid residues involved in the gB-gH-gL complex formation, Blue colored amino acid residues VAL 342, GLU 347, SER 349, TYR 355, SER 388, ASN 395, HIS 398 and ALA 387 belong to gH-gL complex, whereas yellow colored amino acid residues LYS 435, ARG 418, GLN 438, PRO 439, LEU 399, GLU 401 and GLY 437 belong to gB glycoprotein. B) Hypothesized model for initial binding of gH-gL complex to gB at their H2 domain and Domain II respectively.