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Table 4 Effect of SACD, RCD, HCD, and SATD on OPG and RANKL mRNA expression in * OB and bMSC from rats’ tibia

From: Semen astragali complanati- and rhizoma cibotii-enhanced bone formation in osteoporosis rats

Group

n

OPG mRNA expression in OB*

OPG mRNA expression in bMSC*

RANKL mRNA expression in OB

RANKL mRNA expression in bMSC

NC

12

2.07 ± 0.46

7.33 ± 1.82

1.47 ± 0.52

5.84 ± 1.69

Sham

12

2.15 ± 0.66

7.65 ± 2.19

1.60 ± 0.50

6.07 ± 1.79

OVX

12

1.05 ± 0.40b

3.30 ± 1.03b

2.41 ± 0.53b

9.94 ± 2.16b

DES

12

1.98 ± 0.40d

6.92 ± 1.65d

1.70 ± 0.48d

6.26 ± 1.67d

SACD

12

1.82 ± 0.36d

6.44 ± 1.69d

1.83 ± 0.44d

6.87 ± 1.71d

RCD

12

1.43 ± 0.43b, c

5.00 ± 1.46b, d

2.18 ± 0.52a

8.87 ± 1.91b

HCD

11

0.97 ± 0.36b

3.28 ± 1.20b

2.20 ± 0.60a

9.82 ± 1.95b

SATD

11

1.28 ± 0.38b

3.69 ± 1.47b

2.10 ± 0.48a

9.51 ± 1.86b

  1. aCompare with sham control group: P < 0.05.
  2. bCompare with sham control group: P < 0.01.
  3. cCompare with OVX group: P < 0.05.
  4. dCompare with OVX group: P < 0.01.