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Table 3 Effects of SACD, RCD, HCD, and SATD on the protein expression of OPG and RANKL in OB and bMSC from tibia of rats

From: Semen astragali complanati- and rhizoma cibotii-enhanced bone formation in osteoporosis rats

Group

n

The protein expression of OPG in OB

The protein expression of OPG in bMSC

The protein expression of RANKL in OB

The protein expression of RANKL in bMSC

NC

12

1.66 ± 0.42

7.18 ± 1.72

1.08 ± 0.27

4.77 ± 1.82

Sham

12

1.72 ± 0.52

6.48 ± 1.81

1.17 ± 0.28

4.55 ± 1.75

OVX

12

0.76 ± 0.23b

3.06 ± 1.28b

1.82 ± 0.41b

9.06 ± 2.11b

DES

12

1.62 ± 0.38d, c

6.24 ± 1.91d, c

1.23 ± 0.34d, c

5.34 ± 1.54d, c

SACD

12

1.51 ± 0.45d, c

5.70 ± 1.63d, c

1.30 ± 0.30d, c

6.40 ± 1.88a, d, c

RCD

12

1.25 ± 0.41a, d

4.63 ± 1.23b, d

1.77 ± 0.36b

8.04 ± 2.01b

HCD

11

0.72 ± 0.24b

3.10 ± 1.05b

1.87 ± 0.36b

9.14 ± 2.03b

SATD

11

0.94 ± 0.30b

3.60 ± 1.12b

1.75 ± 0.35b

8.74 ± 1.84b

  1. aCompare with sham control group: P < 0.05.
  2. bCompare with sham control group: P < 0.01.
  3. cCompare with OVX group: P < 0.05.
  4. dCompare with OVX group: P < 0.01.