Figure 5From: The plant coumarins auraptene and lacinartin as potential multifunctional therapeutic agents for treating periodontal disease Effect of auraptene and lacinartin on the secretion of IL-8 (A) and TNF-α (B) by human macrophages stimulated with A. actinomycetemcomitans LPS (1 μg/ml). Values are expressed as means ± standard deviations of triplicate assays for a minimum of three independent experiments. Data were analyzed with the Student’s t-test (*: p ≤ 0.05 vs. untreated control, †: p ≤ 0.05 vs. control without auraptene or lacinartin).Back to article page