Table 16 Effect of DAS-77 on antioxidant enzymes in rat brain in the reversibility study
From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Reversibility study | |||||
|---|---|---|---|---|---|---|---|
| Â | Â | GSH (nm/mg) | SOD (u/mg) | CAT (u/mg) | Peroxidase (u/mg) | MDA (nm/mg) | Protein (mg) |
Distilled water | (10 ml/kg) | 3.67 ± 0.70 | 5.36 ± 0.91 | 24.72 ± 4.20 | 1.68 ± 0.29 | 0.25 ± 0.04 | 16.76 ± 0.94 |
DAS-77 | 80 | 2.49 ± 0.41 | 4.36 ± 0.40 | 20.12 ± 1.86 | 1.37 ± 0.13 | 0.28 ± 0.04 | 16.69 ± 1.20 |
DAS-77 | 400 | 2.15 ± 0.27 | 3.53 ± 0.33 | 16.29 ± 1.55 | 1.11 ± 0.11 | 0.33 ± 0.04 | 20.28 ± 1.22 |
DAS-77 | 2000 | 3.35 ± 1.20 | 5.26 ± 1.62 | 24.26 ± 7.49 | 1.65 ± 0.51 | 0.27 ± 0.04 | 20.76 ± 2.90 |