Figure 1

Chemical composition and cytotoxic activity of TC extract. (A) Peaks: 1, taxine A (5.00%); 2, 10-DAB III (1.45%); 3, 9-hydroxyl-13-acetylbaccatin III (9.38%); 4, 7-xyl-10-DAT (9.63%); 5, baccatin III (8.32%); 6, 10-DAT (6.31%); 7, cephalomannine (2.67%); 8, paclitaxel (2.25%). (B) Differences in TC extract cytotoxicity in 5 human cancer cell lines and normal mouse spleen B and T lymphocytes. The cell growth inhibition was quantified by the MTT assay. Cells were treated with 10 μg/ml TC extract for 72 h. The data shown are from 3 independent experiments.