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  1. Content type: Research article

    Our team has identified 17 Boreal forest species from the traditional pharmacopeia of the Eastern James Bay Cree that presented promising in vitro and in vivo biological activities in the context of type 2 dia...

    Authors: Shilin Li, Sarah Pasquin, Hoda M. Eid, Jean-François Gauchat, Ammar Saleem and Pierre S. Haddad

    Citation: BMC Complementary and Alternative Medicine 2018 18:37

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  2. Content type: Research article

    Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective...

    Authors: Victor Kuete, Dominique Ngnintedo, Ghislain W. Fotso, Oğuzhan Karaosmanoğlu, Bonaventure T. Ngadjui, Felix Keumedjio, Samuel O. Yeboah, Kerstin Andrae-Marobela and Hülya Sivas

    Citation: BMC Complementary and Alternative Medicine 2018 18:36

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  3. Content type: Research article

    Skin forms an important part of human innate immune system. Wrinkles, thinning and roughening of skin are some of the symptoms that affect the skin as it ages. Reactive oxygen species induced oxidative stress ...

    Authors: Induja Kalyana Sundaram, Deepika Deeptirekha Sarangi, Vignesh Sundararajan, Shinomol George and Sahabudeen Sheik Mohideen

    Citation: BMC Complementary and Alternative Medicine 2018 18:33

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  4. Content type: Research article

    Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound. However, elucidating the related molecular biological mechanism of how...

    Authors: Le Kuai, Jing-ting Zhang, Yu Deng, Shun Xu, Xun-zhe Xu, Min-feng Wu, Dong-jie Guo, Yu Chen, Ren-jie Wu, Xing-qiang Zhao, Hua Nian, Bin Li and Fu-lun Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:32

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  5. Content type: Research article

    Icariin (ICA), a major ingredient of Epimediumbrevicornum, has various pharmacological activities including central nervous system protective functions such as the improvement of learning and memory function in m...

    Authors: Xiaolong Fu, Shujun Li, Shaoyu Zhou, Qin Wu, Feng Jin and Jingshan Shi

    Citation: BMC Complementary and Alternative Medicine 2018 18:34

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  6. Content type: Research article

    Morinda citrifolia L. that was reported with immunomodulating and cytotoxic effects has been traditionally used to treat multiple illnesses including cancer. An anthraquinone derived from fruits of Morinda citrif...

    Authors: Nadiah Abu, Nur Rizi Zamberi, Swee Keong Yeap, Noraini Nordin, Nurul Elyani Mohamad, Muhammad Firdaus Romli, Nurulfazlina Edayah Rasol, Tamilselvan Subramani, Nor Hadiani Ismail and Noorjahan Banu Alitheen

    Citation: BMC Complementary and Alternative Medicine 2018 18:31

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  7. Content type: Research article

    Because twigs of Cinnamomum cassia (TC) have been reported to exert anti-cancer activity, the mechanistic study for TC’s anti-cancer activity is required. Thus, we elucidated the potential molecular mechanism of ...

    Authors: Gwang Hun Park, Hun Min Song, Su Bin Park, Ho-Jun Son, Yurry Um, Hyun-Seok Kim and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2018 18:28

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  8. Content type: Research article

    Different parts including the latex of Ficus racemosa L. has been used as a medicine for wound healing in the Ayurveda and in the indigenous system of medicine in Sri Lanka. This plant has been evaluated for its ...

    Authors: Nisansala Swarnamali Bopage, G. M. Kamal Bandara Gunaherath, Kithsiri Hector Jayawardena, Sushila Chandrani Wijeyaratne, Ajita Mahendra Abeysekera and Seneviratne Somaratne

    Citation: BMC Complementary and Alternative Medicine 2018 18:29

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  9. Content type: Research article

    Natural products obtained from plants can be potent sources for developing a variety of pharmaceutical products. Allium species have been widely studied for their anti-cancer effects and presented promising resul...

    Authors: Ovgu Isbilen, Nahit Rizaner and Ender Volkan

    Citation: BMC Complementary and Alternative Medicine 2018 18:30

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  10. Content type: Research article

    Oxidative stress as well as bacterial and fungal infections are common source of diseases while plants are source of medication for curative or protective purposes. Hence, aim of study was to compare the pharm...

    Authors: Iram Fatima, Sobia Kanwal and Tariq Mahmood

    Citation: BMC Complementary and Alternative Medicine 2018 18:27

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  11. Content type: Research article

    Overweight and obesity are considered major health problems that contribute to increase mortality and quality of life. Both conditions have a high prevalence across the world reaching epidemic numbers. Our aim...

    Authors: Andrea Maia-Landim, Juan M. Ramírez, Carolina Lancho, María S. Poblador and José L. Lancho

    Citation: BMC Complementary and Alternative Medicine 2018 18:26

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  12. Content type: Research article

    Hepatitis is a liver inflammation caused by different agents and remains a public health problem worldwide. Medicinal plants are an important source of new molecules being considered for treatment of this dise...

    Authors: Anne Marie Endougou Effa, Emilie Gantier, Thierry Hennebelle, Vincent Roumy, Céline Rivière, Théophile Dimo, Pierre Kamtchouing, Pierre Desreumaux and Laurent Dubuquoy

    Citation: BMC Complementary and Alternative Medicine 2018 18:24

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  13. Content type: Research article

    Within the intercultural milieu of medical pluralism, a nexus of worldviews espousing distinct explanatory models of illness, our research aims at exploring factors leading to complementary and alternative med...

    Authors: Szilvia Zörgő, György Purebl and Ágnes Zana

    Citation: BMC Complementary and Alternative Medicine 2018 18:25

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  14. Content type: Research article

    Numerous health benefits have been attributed to the Ginkgo biloba leaf extract (GBLE), one of the most extensively used phytopharmaceutical drugs worldwide. Recently, concerns of the safety of the extract have b...

    Authors: Stefano Bonassi, Giulia Prinzi, Palma Lamonaca, Patrizia Russo, Irene Paximadas, Giuseppe Rasoni, Raffaella Rossi, Marzia Ruggi, Salvatore Malandrino, Maria Sánchez-Flores, Vanessa Valdiglesias, Barbara Benassi, Francesca Pacchierotti, Paola Villani, Martina Panatta and Eugenia Cordelli

    Citation: BMC Complementary and Alternative Medicine 2018 18:22

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  15. Content type: Research article

    Gyejibokryeong-hwan (Guizhi Fuling Wan in China), a mixture of five herbal plants, is a well-known treatment for renal diseases including those associated with climacteric syndrome. However, the genotoxicity of G...

    Authors: Mee-Young Lee, Chang-Seob Seo, Hyekyung Ha, Eunsook Park, Ji-Young Kim and Hyeun-Kyoo Shin

    Citation: BMC Complementary and Alternative Medicine 2018 18:21

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  16. Content type: Research article

    Cupressus macrocarpa Hartw and Corymbia citriodora (Hook.) K.D. Hill & L.A.S. Johnson, widely grown in many subtropical areas, are used for commercial purposes, such as in perfumery, cosmetics, and room freshener...

    Authors: Mohamed Z. M. Salem, Hosam O. Elansary, Hayssam M. Ali, Ahmed A. El-Settawy, Mohamed S. Elshikh, Eslam M. Abdel-Salam and Krystyna Skalicka-Woźniak

    Citation: BMC Complementary and Alternative Medicine 2018 18:23

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  17. Content type: Research article

    Pelargonium sidoides (PS) and Coptis chinensis root (CR) have traditionally been used to treat various diseases, including respiratory and gastrointestinal infections, dysmenorrhea, and hepatic disorders. The pre...

    Authors: Sang Mi Park, Byung-Gu Min, Ji Yun Jung, Kyung Hwan Jegal, Chul Won Lee, Kwang Youn Kim, Young Woo Kim, Youn-Woong Choi, Il Je Cho, Sae Kwang Ku and Sang Chan Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:20

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  18. Content type: Research article

    Although the efficiency of conservative management for lumbar spinal stenosis (LSS) has been examined, different conservative management approaches have not been compared. We have performed the first comparati...

    Authors: Hiroyuki Oka, Ko Matsudaira, Yuichi Takano, Daichi Kasuya, Masaki Niiya, Juichi Tonosu, Masayoshi Fukushima, Yasushi Oshima, Tomoko Fujii, Sakae Tanaka and Hirohiko Inanami

    Citation: BMC Complementary and Alternative Medicine 2018 18:19

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  19. Content type: Study protocol

    It has been suggested that the antioxidant, anti-inflammatory and hypolipidemic activities of cardamom may improve diabetes. However, the effect of this spice has not been investigated in diabetic subjects. Th...

    Authors: Mohadeseh Aghasi, Shohreh Ghazi-Zahedi, Fariba Koohdani, Fereydoun Siassi, Ensieh Nasli-Esfahani, Ali Keshavarz, Mostafa Qorbani, Hoorieh Khoshamal, Asma Salari-Moghaddam and Gity Sotoudeh

    Citation: BMC Complementary and Alternative Medicine 2018 18:18

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  20. Content type: Research article

    Alpinia galanga (L.) Willd. commonly called as Rasna, Greater galangal or Kulinjan is a medicinally important rhizome used in Indian traditional system of medicine to cure a number of ailments. A. galanga is the ...

    Authors: Anuradha S. Upadhye, Anagha Rajopadhye and Lourelle Dias

    Citation: BMC Complementary and Alternative Medicine 2018 18:16

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  21. Content type: Research article

    Based on clinical medications and related studies, we established a Yang-Gan Jie-Du Sang-Jie (YGJDSJ) herbal formula for hepatocarcinoma treatment. In present study, we evaluated the anti-cancer potential of Y...

    Authors: Bing Hu, Tong Zhang, Hong-Mei An, Jia-Lu Zheng, Xia Yan and Xiao-Wei Huang

    Citation: BMC Complementary and Alternative Medicine 2018 18:17

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  22. Content type: Research article

    Nutmeg is the seed kernel inside the fruit of Myristica fragrans Houtt. (Myristicaceae). It possesses various pharmacological activities but is used in Cameroon only for its flavor in making cakes. The present st...

    Authors: Joachim K. Dzotam, Ingrid Konga Simo, Gabin Bitchagno, Ilhami Celik, Louis P. Sandjo, Pierre Tane and Victor Kuete

    Citation: BMC Complementary and Alternative Medicine 2018 18:15

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  23. Content type: Research article

    Fructose-mediated protein glycation (fructation) has been linked to an increase in diabetic and cardiovascular complications due to over consumption of high-fructose containing diets in recent times. The objec...

    Authors: Hardik Ghelani, Valentina Razmovski-Naumovski, Rajeswara Rao Pragada and Srinivas Nammi

    Citation: BMC Complementary and Alternative Medicine 2018 18:13

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  24. Content type: Case report

    Impairment of cognitive function as well as negative symptom is the major factor causing the decline of a patient’s functioning in chronic stages of schizophrenia. However, until now, there were no definite tr...

    Authors: Seung Sun Rho, Young Sup Woo and Won-Myong Bahk

    Citation: BMC Complementary and Alternative Medicine 2018 18:14

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  25. Content type: Research article

    Inflammation has been implicated in many disorders, including cancer and available therapies elicit adverse effects. Plants of the family Rubiaceae have shown potency against inflammation. The anti-inflammator...

    Authors: Oluwayinka Olufunmilayo Owolabi, Dorcas Bolanle James, Ibrahim Sani, Binda T. Andongma, Opeoluwa O. Fasanya and Barnabas Kure

    Citation: BMC Complementary and Alternative Medicine 2018 18:12

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  26. Content type: Research article

    The highbush blueberry (Vaccinium corymbosum) has a beneficial effect on several aspects of human health. The present study investigated the effects of highbush blueberry proanthocyanidins (PACs) on the virulence...

    Authors: Amel Ben Lagha, Geneviève LeBel and Daniel Grenier

    Citation: BMC Complementary and Alternative Medicine 2018 18:10

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  27. Content type: Research article

    Unhealthy lifestyles are a major factor in the development and exacerbation of many chronic diseases. Improving lifestyles though immersive residential experiences that promote healthy behaviours is a focus of...

    Authors: Dhevaksha Naidoo, Adrian Schembri and Marc Cohen

    Citation: BMC Complementary and Alternative Medicine 2018 18:8

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  28. Content type: Research article

    Behavioral studies demonstrated that the administration of Withania somnifera Dunal roots extract (WSE), prolongs morphine-elicited analgesia and reduces the development of tolerance to the morphine’s analgesic e...

    Authors: Francesca Felicia Caputi, Elio Acquas, Sanjay Kasture, Stefania Ruiu, Sanzio Candeletti and Patrizia Romualdi

    Citation: BMC Complementary and Alternative Medicine 2018 18:9

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  29. Content type: Research article

    Many European citizens are seeking complementary and alternative medicine (CAM). These treatments are regulated very differently in the EU/EFTA countries. This may demonstrate differences in how risk associate...

    Authors: Solveig Wiesener, Anita Salamonsen and Vinjar Fønnebø

    Citation: BMC Complementary and Alternative Medicine 2018 18:11

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  30. Content type: Research article

    The aim of this clinical trial was to assess the efficacy and safety of curcuminoid complex extract from turmeric rhizome with turmeric volatile oil (CuraMed®) and its combination with boswellic acid extract f...

    Authors: Armine Haroyan, Vahan Mukuchyan, Nana Mkrtchyan, Naira Minasyan, Srbuhi Gasparyan, Aida Sargsyan, Mikael Narimanyan and Areg Hovhannisyan

    Citation: BMC Complementary and Alternative Medicine 2018 18:7

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  31. Content type: Research article

    Costus speciosus, Cymbopogon citratus, and Tabernaemontana coronaria are herbal plants traditionally used as remedies for symptoms of tuberculosis (TB) including cough. The aims of the present study were to evalu...

    Authors: Suriyati Mohamad, Nur Najihah Ismail, Thaigarajan Parumasivam, Pazilah Ibrahim, Hasnah Osman and Habibah A. Wahab

    Citation: BMC Complementary and Alternative Medicine 2018 18:5

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  32. Content type: Research article

    An impaired leukocytes function is the factor causing the susceptibility of patients with diabetes mellitus to infections. The outmost importance for the understanding of the immunological processes involved i...

    Authors: Mariia Nagalievska, Mariya Sabadashka, Halyna Hachkova and Nataliia Sybirna

    Citation: BMC Complementary and Alternative Medicine 2018 18:4

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  33. Content type: Research article

    Clitoria ternatea L., a natural food-colorant containing anthocyanin, demonstrated antioxidant and antihyperglycemic activity. The aim of this study was to determine the effects of Clitoria ternatea flower extrac...

    Authors: Charoonsri Chusak, Thavaree Thilavech, Christiani Jeyakumar Henry and Sirichai Adisakwattana

    Citation: BMC Complementary and Alternative Medicine 2018 18:6

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  34. Content type: Research article

    Juniperus communis L. represents a multi-purpose crop used in the pharmaceutical, food, and cosmetic industry. Several studies present the possible medicinal properties of different Juniperus taxa native to speci...

    Authors: Irina Fierascu, Camelia Ungureanu, Sorin Marius Avramescu, Carmen Cimpeanu, Mihaela Ioana Georgescu, Radu Claudiu Fierascu, Alina Ortan, Anca Nicoleta Sutan, Valentina Anuta, Anca Zanfirescu, Cristina Elena Dinu-Pirvu and Bruno Stefan Velescu

    Citation: BMC Complementary and Alternative Medicine 2018 18:3

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  35. Content type: Research article

    The medicinal importance of a novel plant Olax nana Wall. ex Benth. (family: Olacaceae) was revealed for the first time via HPLC-DAD finger printing, qualitative phytochemical analysis, antioxidant, cholinesteras...

    Authors: Muhammad Ovais, Muhammad Ayaz, Ali Talha Khalil, Sayed Afzal Shah, Muhammad Saeed Jan, Abida Raza, Muhammad Shahid and Zabta Khan Shinwari

    Citation: BMC Complementary and Alternative Medicine 2018 18:1

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  36. Content type: Research article

    Basophilic granulocytes (BGs) not only initiate the induction of Th2 cell differentiation, but also amplify the ongoing Th2 response. Shuang-Huang-Lian (SHL) is clinically used for relieving type I hypersensit...

    Authors: Qiaoling Fei, Yixin Han, Ruijuan Qi, Yuan Gao, Lei Fang, Rui Hou, Runlan Cai and Yun Qi

    Citation: BMC Complementary and Alternative Medicine 2018 18:2

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  37. Content type: Research article

    The use of doxorubicin (DOX) an anthracycline antineoplastic agent is withdrawn due to its cardio-toxic side effects. Oxidative stress has been recognized as the primary cause of DOX induced cardiotoxicity. We...

    Authors: Tayyaba Afsar, Suhail Razak, Khalid Mujasam Batoo and Muhammad Rashid Khan

    Citation: BMC Complementary and Alternative Medicine 2017 17:554

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  38. Content type: Research article

    The conversion of the epithelial phenotype of cancer cells into cells with a mesenchymal phenotype-so-called epithelial–mesenchymal transition (EMT)-has been shown to enhance the capacity of the cells to disse...

    Authors: Nareerat Petpiroon, Boonchoo Sritularak and Pithi Chanvorachote

    Citation: BMC Complementary and Alternative Medicine 2017 17:553

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  39. Content type: Research article

    Danshen is a common traditional Chinese medicine used to treat neoplastic and chronic inflammatory diseases in China. However, the effects of Danshen on human oral cancer cells remain relatively unknown. This ...

    Authors: Cheng-Yu Yang, Cheng-Chih Hsieh, Chih-Kung Lin, Chun-Shu Lin, Bo Peng, Gu-Jiun Lin, Huey-Kang Sytwu, Wen-Liang Chang and Yuan-Wu Chen

    Citation: BMC Complementary and Alternative Medicine 2017 17:555

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  40. Content type: Research article

    Alzheimer’s disease (AD) is the most common cause of dementia. However, none of medical treatment can stop or reverse the underlying neurodegenerative of AD at present. Acupuncture has attracted more and more ...

    Authors: Yujie Jia, Xuezhu Zhang, Jianchun Yu, Jingxian Han, Tao Yu, Jiangwei Shi, Lan Zhao and Kun Nie

    Citation: BMC Complementary and Alternative Medicine 2017 17:556

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  41. Content type: Research article

    Cinnamon is considered as a treatment for many ailments in native medicine. Evidence suggests that Cinnamomum zeylanicum (CZ) has anti-microbial, anti-parasitic, anti-oxidant, blood glucose lowering properties an...

    Authors: Priyanga Ranasinghe, Ranil Jayawardena, Shehani Pigera, Wasundara Sevwandi Wathurapatha, Hasitha Dhananjaya Weeratunga, G. A. Sirimal Premakumara, Prasad Katulanda, Godwin Roger Constantine and Priyadarshani Galappaththy

    Citation: BMC Complementary and Alternative Medicine 2017 17:550

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  42. Content type: Research article

    Although such local herb as Streblus asper (family Moraceae) has long been recognized for traditional folk medicines and important ingredient of traditional longevity formula, its anti-neurodegeneration or anti-a...

    Authors: Anchalee Prasansuklab, Krai Meemon, Prasert Sobhon and Tewin Tencomnao

    Citation: BMC Complementary and Alternative Medicine 2017 17:551

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  43. Content type: Correction

    After the publication of this article [1] it came to our attention that Harquin Simplice Foyet was incorrectly included as Harquin Simplice Harquin Foyet. The corrected name is included in the author list. The...

    Authors: Harquin Simplice Foyet, Serge Tchinda Deffo, Pascaline Koagne Yewo, Iulia Antioch, Stéphane Zingue, Emmanuel Acha Asongalem, Pierre Kamtchouing and Alin Ciobica

    Citation: BMC Complementary and Alternative Medicine 2017 17:552

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    The original article was published in BMC Complementary and Alternative Medicine 2017 17:502

  44. Content type: Research article

    Mood disorder accounts for 13 % of global disease burden. And while therapeutic agents are available, usually orally administered, most have unwanted side effects, and thus making the inhalation of essential o...

    Authors: Myra O. Villareal, Ayumi Ikeya, Kazunori Sasaki, Abdelkarim Ben Arfa, Mohamed Neffati and Hiroko Isoda

    Citation: BMC Complementary and Alternative Medicine 2017 17:549

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  45. Content type: Research article

    Integrative health care (IHC) is an innovative approach to health care delivery. There is increasing focus on and demand for the evaluation of IHC practices. To ensure such evaluations capture their full scope...

    Authors: Ania Kania-Richmond and Amy Metcalfe

    Citation: BMC Complementary and Alternative Medicine 2017 17:548

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  46. Content type: Research article

    Kampo medicine is traditional Japanese medicine, which originated in ancient traditional Chinese medicine, but was introduced and developed uniquely in Japan. Today, Kampo medicines are integrated into the Jap...

    Authors: Yutaka Shimada, Makoto Fujimoto, Tatsuya Nogami, Hidetoshi Watari, Hideyuki Kitahara, Hiroki Misawa and Yoshiyuki Kimbara

    Citation: BMC Complementary and Alternative Medicine 2017 17:547

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  47. Content type: Research article

    Extracts from Salvia miltiorrhiza Bunge have been used in traditional Asian medicine to treat coronary heart disease, chronic renal failure, atherosclerosis, myocardial infraction, angina pectoris, myocardial isc...

    Authors: Bongkyun Park, Hae Seong Song, Jeong Eun Kwon, Se Min Cho, Seon-A Jang, Mi Yeon Kim and Se Chan Kang

    Citation: BMC Complementary and Alternative Medicine 2017 17:545

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  48. Content type: Research article

    Osteopathic manipulative treatment (OMT) of the sphenopalatine ganglion (SPG) is used empirically for the treatment of rhinitis and snoring and is thought to increase pharyngeal stability. This trial was desig...

    Authors: Olivier Jacq, Isabelle Arnulf, Thomas Similowski and Valérie Attali

    Citation: BMC Complementary and Alternative Medicine 2017 17:546

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  49. Content type: Research article

    Pregnant women are routinely prescribed medicines while self-medicating with herbal natural products to treat predominantly pregnancy related conditions. The aim of this study was to assess the potential for h...

    Authors: James S. McLay, Naila Izzati, Abdul R. Pallivalapila, Ashalatha Shetty, Binita Pande, Craig Rore, Moza Al Hail and Derek Stewart

    Citation: BMC Complementary and Alternative Medicine 2017 17:543

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  50. Content type: Research article

    Acute kidney injury (AKI) is an initial factor in many kidney disorders. Pre- and intra-renal AKI biomarkers have recently been reported. Recovery from AKI by herbal medicine has rarely been reported. Thus, th...

    Authors: Sung-Man Oh, Gunhyuk Park, Seung Hoon Lee, Chang-Seob Seo, Hyeun-Kyoo Shin and Dal-Seok Oh

    Citation: BMC Complementary and Alternative Medicine 2017 17:544

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