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  1. Content type: Research article

    Influenza infection remains a major health threat for animals and humans which crucially requires effective antiviral remedies. The usage of herbal medications as readily available alternatives for their compa...

    Authors: Parvaneh Mehrbod, Muna A. Abdalla, Emmanuel M. Njoya, Aroke S. Ahmed, Fatemeh Fotouhi, Behrokh Farahmand, Dorcas A. Gado, Mansoureh Tabatabaian, Olubunmi G. Fasanmi, Jacobus N. Eloff, Lyndy J. McGaw and Folorunso O. Fasina

    Citation: BMC Complementary and Alternative Medicine 2018 18:112

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  2. Content type: Research article

    Japanese herbal medicines can be used as alternatives to estrogen therapy and are sometimes prescribed for menopausal syndrome because they have fewer side effects and are associated with better compliance tha...

    Authors: Zeyun Wang, Seiji Kanda, Takaki Shimono, Dambajamts Enkh-Undraa and Toshimasa Nishiyama

    Citation: BMC Complementary and Alternative Medicine 2018 18:107

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  3. Content type: Research article

    Antrodia cinnamomea is an indigenous medicinal mushroom in Taiwan, commonly used for the treatment of cancers and inflammatory disorders. 4-acetylantroquinonol B (4AAQB) is one of the active component isolated fr...

    Authors: Chien-Hsin Chang, Chun-Chieh Hsu, An-Sheng Lee, Shih-Wei Wang, Kung-Tin Lin, Wei-Luen Chang, Hui-Chin Peng, Wen-Chiung Huang and Ching-Hu Chung

    Citation: BMC Complementary and Alternative Medicine 2018 18:108

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  4. Content type: Research article

    Dependence on antipsycotic drugs like aripriprazole (ARI) is increasing at alarming rate, hence, this study was undertaken to support the hypothesis that supplementation of Citrus paradisi (Grapefruit) juice havi...

    Authors: Seema Zargar, Abdul-Rahman A. Al-Majed and Tanveer A. Wani

    Citation: BMC Complementary and Alternative Medicine 2018 18:106

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  5. Content type: Research article

    MicroRNAs(miRNAs)are involved in the initiation and progression of hepatocellular carcinoma. ESC, an extract of Stellerachamaejasme L, had been confirmed as a potential anti-tumor extract of Traditional Chinese M...

    Authors: Xiaoni Liu, Shuang Wang, Jianji Xu, Buxin Kou, Dexi Chen, Yajie Wang and Xiaoxin Zhu

    Citation: BMC Complementary and Alternative Medicine 2018 18:99

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  6. Content type: Research article

    Allium fistulosum (Welsh onion) is a traditional medicinal plant used for the treatment of colds, influenza, abdominal pain, headache, and heart disease. This study evaluated the effects of A. fistulosum ethanoli...

    Authors: Yoon-Young Sung, Dong-Seon Kim, Seung-Hyung Kim and Ho Kyoung Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:105

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  7. Content type: Research article

    Neuraminidase (NA) is one of the key surface protein of the influenza virus, and has been established as a primary drug target for anti-influenza therapies. This study aimed to screen bioactive herbal extracts...

    Authors: Jiawei Liu, Mian Zu, Kaotan Chen, Li Gao, Huan Min, Weiling Zhuo, Weiwen Chen and Ailin Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:102

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  8. Content type: Research article

    Apium graveolens L. is a traditional Chinese medicine prescribed as a treatment for hypertension, gout, and diabetes. This study aimed to determine the neuroprotective effects of A. graveolens extract against a P...

    Authors: Pennapa Chonpathompikunlert, Phetcharat Boonruamkaew, Wanida Sukketsiri, Pilaiwanwadee Hutamekalin and Morakot Sroyraya

    Citation: BMC Complementary and Alternative Medicine 2018 18:103

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  9. Content type: Research article

    No animal model studies have been conducted in which the efficacy of herbal compounds has been tested against multidrug-resistant Acinetobacter baumannii infections. Very few antibiotics are available for the tre...

    Authors: Chin-Chuan Tsai, Chi-Shiuan Lin, Chun-Ru Hsu, Chiu-Ming Chang, I-Wei Chang, Li-Wei Lin, Chih-Hsin Hung and Jiun-Ling Wang

    Citation: BMC Complementary and Alternative Medicine 2018 18:96

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  10. Content type: Research article

    To evaluate the efficacy and tolerability of a poly-herbal formulation, Herbagut, for the treatment of gastrointestinal symptoms and its effect on quality of life parameters in patients presenting with self-re...

    Authors: Adrian L. Lopresti, Hemant Gupta and Stephen J. Smith

    Citation: BMC Complementary and Alternative Medicine 2018 18:98

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  11. Content type: Research article

    Lung adenocarcinoma is the most common subtype of Non small cell lung cancer in which the PI3K/Akt cascade is frequently deregulated. The ubiquitous expression of the PI3K and the frequent inactivation of PTEN...

    Authors: Fazeela Mahaboob Begum S.M., Kalai Chitra, Benin Joseph, Raji Sundararajan and Hemalatha S.

    Citation: BMC Complementary and Alternative Medicine 2018 18:104

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  12. Content type: Research article

    Laminaria japonica has frequently been used as a food supplement and drug in traditional oriental medicine. Among the major active constituents responsible for the bioactivities of L. japonica, fucoxanthin (FX) h...

    Authors: Eun Jeong Jang, Sang Chan Kim, Ju-Hee Lee, Jong Rok Lee, Il Kon Kim, Su Youn Baek and Young Woo Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:97

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  13. Content type: Research article

    Zingiber zerumbet (L.) Smith belongs to the Zingiberaceae family that is widely distributed throughout the tropics, particularly in Southeast Asia. It is locally known as ‘Lempoyang’ and traditionally used to tre...

    Authors: Asmah Hamid, Farah Wahida Ibrahim, Teoh Hooi Ming, Mohd Nazir Nasrom, Norelina Eusoff, Khairana Husain and Mazlyzam Abdul Latif

    Citation: BMC Complementary and Alternative Medicine 2018 18:101

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  14. Content type: Research article

    It is well known that endoplasmic reticulum (ER) stress plays a huge role in development of metabolic diseases. Specially, ER stress-induced cellular dysfunction has a significant involvement in the pathogenes...

    Authors: Hwa Yeon Kim, Ha Na Song, Munkhtugs Davaatseren, Hyun Joo Chang and Hyang Sook Chun

    Citation: BMC Complementary and Alternative Medicine 2018 18:100

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  15. Content type: Research article

    Urtica dioica, Taraxacum officinale, Calea integrifolia and Caesalpinia pulcherrima are widely used all over the world for treatment of different illnesses. In Mexico, these plants are traditionally used to allev...

    Authors: María R. Flores-Ocelotl, Nora H. Rosas-Murrieta, Diego A. Moreno, Verónica Vallejo-Ruiz, Julio Reyes-Leyva, Fabiola Domínguez and Gerardo Santos-López

    Citation: BMC Complementary and Alternative Medicine 2018 18:95

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  16. Content type: Research article

    Sutherlandia frutescens (L.) R. Br is endemic to Southern Africa where it has been traditionally used for cancer and diabetes. In recent times it has been marketed for its reputed (but not proven) anticancer, ant...

    Authors: Siyabulela S. B. N. Ntuli, Wentzel C. A. Gelderblom and David R. Katerere

    Citation: BMC Complementary and Alternative Medicine 2018 18:93

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  17. Content type: Research article

    The use of herbal medicine, as one element of complementary and alternative medicine, is increasing worldwide. Little is known about the reasons for and factors associated with its use. This study derives insi...

    Authors: Alexandra N. Welz, Agnes Emberger-Klein and Klaus Menrad

    Citation: BMC Complementary and Alternative Medicine 2018 18:92

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  18. Content type: Research article

    The anti-tumor activities of Natural compounds and their derivatives are of great interest to pharmaceutical industries. Fisetin is one of prospective natural compounds in this regard but unfortunately with po...

    Authors: Xue Xiao, Juan Zou, Yin Fang, Yibo Meng, Chao Xiao, Jiaxin Fu, Shiyu Liu, Peng Bai and Yuan Yao

    Citation: BMC Complementary and Alternative Medicine 2018 18:91

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  19. Content type: Research article

    Phyllanthus amarus (Schum & Thonn), a plant belonging to the family of Euphorbiaceae is used in Ivorian traditional medicine to treat cardiovascular disorders such as hypertension. However, although this plant ha...

    Authors: Alain N’guessan Yao, Mamadou Kamagaté, Augustin Kouao Amonkan, Philippe Chabert, Fidèle Kpahé, Camille Koffi, Mathieu N’goran Kouamé, Cyril Auger, Séraphin Kati-Coulibaly, Valérie Schini-Kerth and Henri Die-Kakou

    Citation: BMC Complementary and Alternative Medicine 2018 18:94

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  20. Content type: Research article

    The aim of this study was to investigate autism spectrum disorder (ASD) clinical practice patterns of Korean medicine doctors (KMDs) through questionnaire survey.

    Authors: Jihong Lee, Sun Haeng Lee, Boram Lee, In Jun Yang and Gyu Tae Chang

    Citation: BMC Complementary and Alternative Medicine 2018 18:90

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  21. Content type: Research article

    Khaya grandifoliola (C.D.C.) stem bark, Cymbopogon citratus (Stapf) and Cryptolepis sanguinolenta (Lindl.) Schltr leaves are used in Cameroonian traditional medicine for the treatment of inflammatory diseases. Se...

    Authors: Francine Kengne Mediesse, Thaddée Boudjeko, Anantharaju Hasitha, Matharasala Gangadhar, Wilfred Fon Mbacham and Perumal Yogeeswari

    Citation: BMC Complementary and Alternative Medicine 2018 18:86

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  22. Content type: Research article

    Ardisia crispa Thunb. D.C is used mostly in some parts of the Asian region by traditional practitioners to treat certain diseases associated with oxidative stress and inflammation including cancer and rheumatism....

    Authors: Muhammad Luqman Nordin, Arifah Abdul Kadir, Zainul Amiruddin Zakaria, Rasedee Abdullah and Muhammad Nazrul Hakim Abdullah

    Citation: BMC Complementary and Alternative Medicine 2018 18:87

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  23. Content type: Research article

    A significant proportion of cancer patients use complementary and alternative medicine (CAM) along with conventional therapies (CT), whereas a smaller proportion delay or defer CT in favor of CAM. Previous stu...

    Authors: Khadega A. Abuelgasim, Yousef Alsharhan, Tariq Alenzi, Abdulaziz Alhazzani, Yosra Z. Ali and Abdul Rahman Jazieh

    Citation: BMC Complementary and Alternative Medicine 2018 18:88

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  24. Content type: Research article

    Oxidative stress in an intracellular environment created by the accumulation of reactive oxygen species results in oxidative damage to biomolecules which ultimately become a hallmark for severe diseases like c...

    Authors: Riveka Rani, Saroj Arora, Jeevanjot Kaur and Rajesh Kumari Manhas

    Citation: BMC Complementary and Alternative Medicine 2018 18:82

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  25. Content type: Research article

    This study showed phytochemical composition and evaluates the anti-inflammatory, and analgesic activities of crude extract (CE) and fractions from E. uniflora Linn leaves.

    Authors: Tamires Rocha Falcão, Aurigena Antunes de Araújo, Luiz Alberto Lira Soares, Rhayanne Thaís de Moraes Ramos, Isabelle Cristinne Ferraz Bezerra, Magda Rhayanny Assunção Ferreira, Manoel André de Souza Neto, Maria Celeste Nunes Melo, Raimundo Fernandes de Araújo Jr, Andreza Conceição Véras de Aguiar Guerra, Juliana Silva de Medeiros and Gerlane Coelho Bernardo Guerra

    Citation: BMC Complementary and Alternative Medicine 2018 18:84

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  26. Content type: Research article

    Astragalus membranaceus (AM) is a commonly used herb in traditional Chinese medicine (TCM), which has been used as an essential tonic to treat various diseases for more than 2000 years. In this study, we aimed to...

    Authors: Ruijuan Zhou, Hongjiu Chen, Junpeng Chen, Xuemei Chen, Yu Wen and Leqin Xu

    Citation: BMC Complementary and Alternative Medicine 2018 18:83

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  27. Content type: Research article

    Type 2 Diabetes Mellitus (T2DM) patients are increasingly using herbal remedies due to the fact that sticking to the therapeutic regimens is becoming awkward. However, studies towards herbal medicine use by di...

    Authors: Abebe Basazn Mekuria, Sewunet Admasu Belachew, Henok Getachew Tegegn, Dawit Simegnew Ali, Adeladlew Kassie Netere, Eskedar Lemlemu and Daniel Asfaw Erku

    Citation: BMC Complementary and Alternative Medicine 2018 18:85

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  28. Content type: Research article

    Salix aegyptiaca is known for its medicinal properties mainly due to the presence of salicylate compounds. However, it also contains other beneficial phytochemicals such as gallic acid, quercetin, rutin and vanil...

    Authors: Mohd Nauman, R. K. Kale and Rana P. Singh

    Citation: BMC Complementary and Alternative Medicine 2018 18:81

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  29. Content type: Research article

    To explore if health related quality of life(HRQoL) increased after traditional yoga(TY), mindfulness based cognitive therapy(MBCT), or cognitive behavioral therapy(CBT), in patients on sick leave because of b...

    Authors: Astrid Grensman, Bikash Dev Acharya, Per Wändell, Gunnar H. Nilsson, Torkel Falkenberg, Örjan Sundin and Sigbritt Werner

    Citation: BMC Complementary and Alternative Medicine 2018 18:80

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  30. Content type: Research article

    α-glucosidase is a therapeutic target for diabetes mellitus (DM) and α-glucosidase inhibitors play a vital role in the treatments for the disease. Furthermore, xanthine oxidase (XO) is a key enzyme that cataly...

    Authors: Habib Mosbah, Hassiba Chahdoura, Jannet Kammoun, Malek Besbes Hlila, Hanen Louati, Saoussen Hammami, Guido Flamini, Lotfi Achour and Boulbaba Selmi

    Citation: BMC Complementary and Alternative Medicine 2018 18:79

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  31. Content type: Research article

    Semecarpus parvifolia Thw is used as an ingredient of poly herbal decoctions to treat cancer in traditional medicine. The present study aims to investigate the antiproliferative activity on HEp 2 cells by the wat...

    Authors: Preethi Soysa, Panchima Jayarthne and Imali Ranathunga

    Citation: BMC Complementary and Alternative Medicine 2018 18:78

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  32. Content type: Research article

    Extensive epidemiological and clinical studies revealed that Alzheimer’s Disease (AD) and Type 2 Diabetes Mellitus (T2D) are most likely to appear simultaneously in aged people as T2D is a major risk factor fo...

    Authors: Mohan Penumala, Raveendra Babu Zinka, Jeelan Basha Shaik, Suresh Kumar Reddy Mallepalli, Ramakrishna Vadde and Damu Gangaiah Amooru

    Citation: BMC Complementary and Alternative Medicine 2018 18:77

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  33. Content type: Research article

    Cordyceps militaris (C. militaris) is reported to exert various immune-activities. To enhance its activity, we fermented C.militaris with Pediococcus pentosaceus ON89A (GRC-ON89A). In this study, we investigated ...

    Authors: Ha-Kyoung Kwon, Woo-Ri Jo and Hye-Jin Park

    Citation: BMC Complementary and Alternative Medicine 2018 18:75

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  34. Content type: Research article

    Methamphetamine (METH) is a psychostimulant with high abuse liability that affects the monoamine neurotransmitter systems, particularly the dopamine system. Currently there are no effective medications for the...

    Authors: Shasha Xu, Shaoang Tu, Jinlong Gao, Jia Liu, Zhirui Guo, Jinming Zhang, Xingdang Liu, Jianhui Liang, Yiyun Huang and Mei Han

    Citation: BMC Complementary and Alternative Medicine 2018 18:76

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  35. Content type: Research article

    Uses of polyherbal formulations have played a major role in traditional medicine. The present study is focused on the formulations used in traditional Thai folkloric medicine as tonics or bracers. Twenty docum...

    Authors: Wipawee Chanthasri, Nuntitporn Puangkeaw, Nongluk Kunworarath, Patcharawalai Jaisamut, Surasak Limsuwan, Katesarin Maneenoon, Piyapong Choochana and Sasitorn Chusri

    Citation: BMC Complementary and Alternative Medicine 2018 18:73

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  36. Content type: Research article

    Cumulated evidence reveals that glial cells in the spinal cord play an important role in the development of chronic neuropathic pain and are also complicated in the analgesic effect of EA intervention. But the...

    Authors: Jun-ying Wang, Yong-hui Gao, Li-na Qiao, Jian-liang Zhang, Cheng-Lin Duan-mu, Ya-xia Yan, Shu-ping Chen and Jun-ling Liu

    Citation: BMC Complementary and Alternative Medicine 2018 18:74

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  37. Content type: Research article

    Pancreatic cancer is one of the leading causes of cancer related death and its incidence has risen steadily. Although anticancer drugs have been developed based on the new molecular findings, the drugs have pr...

    Authors: Maiyon Park, Danielle Upton, Melodie Blackmon, Valerie Dixon, Scott Craver, Dawn Neal and Derek Perkins

    Citation: BMC Complementary and Alternative Medicine 2018 18:71

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  38. Content type: Research article

    Evidence suggests that fasting, during which only water is consumed, results in potentially health promoting physiological effects. However, peer-reviewed research assessing the safety of water-only fasting is...

    Authors: John S. Finnell, Bradley C. Saul, Alan C. Goldhamer and Toshia R. Myers

    Citation: BMC Complementary and Alternative Medicine 2018 18:67

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  39. Content type: Research article

    Spinacia oleracea is an important dietary vegetable in India and throughout the world and has many beneficial effects. It is cultivated globally. However, its effect on osteoarthritis that mainly targets the cart...

    Authors: Dharmendra Choudhary, Priyanka Kothari, Ashish Kumar Tripathi, Sonu Singh, Sulekha Adhikary, Naseer Ahmad, Sudhir Kumar, Kapil Dev, Vijay Kumar Mishra, Shubha Shukla, Rakesh Maurya, Prabhat R. Mishra and Ritu Trivedi

    Citation: BMC Complementary and Alternative Medicine 2018 18:69

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  40. Content type: Research article

    Zanthoxylum armatum DC is an important medicinal plant of south East Asia, and has been used to treat various ailments in traditional medicine including diabetes. This study investigated the in vitro and in vivo ...

    Authors: Fiaz Alam, Qazi Najam us Saqib and Mohammad Ashraf

    Citation: BMC Complementary and Alternative Medicine 2018 18:68

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  41. Content type: Research article

    Bauhinia kockiana originates from Peninsular Malaysia and it is grown as a garden ornamental plant. Our previous study reported that this plant exhibited fairly strong antioxidant and antimicrobial activities. Th...

    Authors: Yik Ling Chew, Adlina Maisarah Mahadi, Kak Ming Wong and Joo Kheng Goh

    Citation: BMC Complementary and Alternative Medicine 2018 18:70

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  42. Content type: Research article

    Depression is a common mental disorder. Chai Hu Shu Gan San, a traditional Chinese medicine, is used to treat depression empirically. We present a systematic review and meta-analysis of the therapeutic efficac...

    Authors: Yan Sun, Xia Xu, Jinping Zhang and Yuanyuan Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:66

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  43. Content type: Research article

    In 2010, the World Health Organization published benchmarks for training in osteopathy in which osteopathic visceral techniques are included. The purpose of this study was to identify and critically appraise t...

    Authors: Albin Guillaud, Nelly Darbois, Richard Monvoisin and Nicolas Pinsault

    Citation: BMC Complementary and Alternative Medicine 2018 18:65

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  44. Content type: Correction

    After the publication [1] it came to the attention of the authors that one of the co-authors was incorrectly included as Hamza Somrain. The correct spelling is as follows: Hamzeh Sumrein.

    Authors: Malek Zihlif, Fatma Afifi, Rana Abu-Dahab, Amin Malik Shah Abdul Majid, Hamza Somrain, Mohanad M. Saleh, Zeyad D. Nassar and Randa Naffa

    Citation: BMC Complementary and Alternative Medicine 2018 18:64

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    The original article was published in BMC Complementary and Alternative Medicine 2013 13:358

  45. Content type: Research article

    Traditional healing practice is an important and integral part of healthcare systems in almost all countries of the world. Very few studies have addressed the holistic scenario of traditional healing practices...

    Authors: Md. Imdadul Haque, A. B. M. Alauddin Chowdhury, Md. Shahjahan and Md. Golam Dostogir Harun

    Citation: BMC Complementary and Alternative Medicine 2018 18:62

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  46. Content type: Research article

    The thyroid gland is one of the largest endocrine glands in the body. The vast majority of TCs (> 90%) originate from follicular cells and are defined as differentiated thyroid cancers (DTC) and the two histol...

    Authors: Angelica Perna, Antonio De Luca, Laura Adelfi, Tammaro Pasquale, Bruno Varriale and Teresa Esposito

    Citation: BMC Complementary and Alternative Medicine 2018 18:63

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  47. Content type: Research article

    Parkinson’s disease (PD) is a progressive neurodegenerative disorder of the central nervous system. Although the causes of PD pathogenesis remain incomplete, some evidences has suggested that oxidative stress ...

    Authors: Joana Silva, Celso Alves, Susete Pinteus, Susana Mendes and Rui Pedrosa

    Citation: BMC Complementary and Alternative Medicine 2018 18:58

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  48. Content type: Research article

    Gigantol is a bibenzyl compound derived from several medicinal orchids. This biologically active compound has been shown to have promising therapeutic potential against cancer cells, but its mechanism of actio...

    Authors: Shubin Yu, Zhongyuan Wang, Zijie Su, Jiaxing Song, Liang Zhou, Qi Sun, Shanshan Liu, Shiyue Li, Ying Li, Meina Wang, Guo-Qiang Zhang, Xue Zhang, Zhong-Jian Liu and Desheng Lu

    Citation: BMC Complementary and Alternative Medicine 2018 18:59

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