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  1. Research article

    Evidence based anti-osteoporosis effects of Periplaneta americana L on osteoblasts, osteoclasts, vascular endothelial cells and bone marrow derived mesenchymal stem cells

    Kangfuxin (KFX) is the ethanol extract of Periplaneta americana L, which has been widely used in the Traditional Chinese Medicine for the repair and regeneration of injured organ and tissues with long history. Th...

    Yan-Fen Huang, Long-Jian Li, Si-Qian Gao, Yang Chu, Jie Niu, Fu-Neng Geng, Yong-Mei Shen and Li-Hua Peng

    BMC Complementary and Alternative Medicine 2017 17:413

    Published on: 18 August 2017

  2. Research article

    Neuroprotective properties of curcumin in toxin-base animal models of Parkinson’s disease: a systematic experiment literatures review

    Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is widely used in Southeast Asia, China and India in food preparation and for medicinal purposes. Meanwhile, the neuroprotective ...

    Xin-Shi Wang, Zeng-Rui Zhang, Man-Man Zhang, Miao-Xuan Sun, Wen-Wen Wang and Cheng-Long Xie

    BMC Complementary and Alternative Medicine 2017 17:412

    Published on: 17 August 2017

  3. Research article

    Hepatoprotective and antioxidant effects of single clove garlic against CCl4-induced hepatic damage in rabbits

    The increase in demand and consumption of single clove garlic or ‘Solo garlic’ (Allium sativum) has resulted in an increase in research on its therapeutic properties. The present study aims to evaluate the antiox...

    Khalid Mohammed Naji, Elham Shukri Al-Shaibani, Fatima A. Alhadi, Safa’a Abdulrzaq Al-Soudi and Myrene R. D’souza

    BMC Complementary and Alternative Medicine 2017 17:411

    Published on: 17 August 2017

  4. Research article

    Blood pressure-lowering effect of Shinrin-yoku (Forest bathing): a systematic review and meta-analysis

    Shinrin-yoku (experiencing the forest atmosphere or forest bathing) has received increasing attention from the perspective of preventive medicine in recent years. Some studies have rep...

    Yuki Ideno, Kunihiko Hayashi, Yukina Abe, Kayo Ueda, Hiroyasu Iso, Mitsuhiko Noda, Jung-Su Lee and Shosuke Suzuki

    BMC Complementary and Alternative Medicine 2017 17:409

    Published on: 16 August 2017

  5. Research article

    The protective effects of Resveratrol against radiation-induced intestinal injury

    Intestinal injury is a potential cause of death after high-dose radiation exposure. The aim of the present study was to investigate the protective effects of resveratrol against radiation-induced small intesti...

    Heng Zhang, Hao Yan, Xiaoliang Zhou, Huaqing Wang, Yiling Yang, Junling Zhang and Hui Wang

    BMC Complementary and Alternative Medicine 2017 17:410

    Published on: 16 August 2017

  6. Research article

    Comprehensive evaluation of gene expression signatures in response to electroacupuncture stimulation at Zusanli (ST36) acupoint by transcriptomic analysis

    Electroacupuncture (EA) has been applied to treat and prevent diseases for years. However, molecular events happened in both the acupunctured site and the internal organs after EA stimulation have not been cla...

    Jing-Shan Wu, Hsin-Yi Lo, Chia-Cheng Li, Feng-Yuan Chen, Chien-Yun Hsiang and Tin-Yun Ho

    BMC Complementary and Alternative Medicine 2017 17:406

    Published on: 15 August 2017

  7. Research article

    Phytochemical analysis and in vitro anthelmintic activity of Lophira lanceolata (Ochnaceae) on the bovine parasite Onchocerca ochengi and on drug resistant strains of the free-living nematode Caenorhabditis elegans

    Onchocerciasis is one of the tropical neglected diseases (NTDs) caused by the nematode Onchocerca volvulus. Control strategies currently in use rely on mass administration of ivermectin, which has marked activity...

    Justin Kalmobé, Dieudonné Ndjonka, Djafsia Boursou, Jacqueline Dikti Vildina and Eva Liebau

    BMC Complementary and Alternative Medicine 2017 17:404

    Published on: 14 August 2017

  8. Research article

    Antihyperlipidaemic and hepatoprotective activities of acidic and enzymatic hydrolysis exopolysaccharides from Pleurotus eryngii SI-04

    Hyperlipidaemia is the major risk factor contributing to the development and progression of atherosclerosis, fatty liver and cerebrovascular disease. Pleurotus eryngii (P. eryngii) is rich in biologically active ...

    Chen Zhang, Juan Li, Jing Wang, Xingling Song, Jianjun Zhang, Shang Wu, Chunlong Hu, Zhiyuan Gong and Le Jia

    BMC Complementary and Alternative Medicine 2017 17:403

    Published on: 14 August 2017

  9. Research article

    Conessine as a novel inhibitor of multidrug efflux pump systems in Pseudomonas aeruginosa

    Holarrhena antidysenterica has been employed as an ethnobotanical plant for the treatment of dysentery, diarrhoea, fever, and bacterial infections. Biological activities of the princip...

    Thanyaluck Siriyong, Potjanee Srimanote, Sasitorn Chusri, Boon-ek Yingyongnarongkul, Channarong Suaisom, Varomyalin Tipmanee and Supayang Piyawan Voravuthikunchai

    BMC Complementary and Alternative Medicine 2017 17:405

    Published on: 14 August 2017

  10. Research article

    Effect of electromagnetic fields on human osteoarthritic and non-osteoarthritic chondrocytes

    Studies of the effects of electromagnetic fields (EMFs) on cartilaginous cells show a broad range of outcomes. However EMFs are not yet clinically applied as standard treatment of osteoarthritis, as EMF effect...

    Julia Isabelle Redeker, Bärbel Schmitt, Nele Pascale Grigull, Christian Braun, Andreas Büttner, Volkmar Jansson and Susanne Mayer-Wagner

    BMC Complementary and Alternative Medicine 2017 17:402

    Published on: 14 August 2017

  11. Research article

    Effects of Chinese medicinal herbs on expression of brain-derived Neurotrophic factor (BDNF) and its interaction with human breast cancer MDA-MB-231 cells and endothelial HUVECs

    Our previous study demonstrated that an up-regulation of the Brain-Derived Neurotrophic Factor (BDNF) signaling pathway is involved the mechanism causing the recurrence of triple negative breast cancer. The ai...

    Jen-Hwey Chiu, Fang-Pey Chen, Yi-Fang Tsai, Man-Ting Lin, Ling-Ming Tseng and Yi-Ming Shyr

    BMC Complementary and Alternative Medicine 2017 17:401

    Published on: 12 August 2017

  12. Research article

    Anthelminthic properties of Methylene chloride-methanol (1:1) extracts of two Cameroonians medicinal plants on Heligmosomoides bakeri (Nematoda: Heligmosomatidea)

    The resistance of some medico-veterinary parasite strains as well as the unavailability and toxicity of synthetic anthelminthics on humans, animals and the impacts of their residues in the environment have pus...

    Sergine Errole Ngouateu Teufack, Gertrude NMbogning Tayo, Marc Ngangout Alidou, Jeannette Yondo, Amely Frankline Djiomene, Josué Wabo Poné and Faùily Mpoame Mbida

    BMC Complementary and Alternative Medicine 2017 17:400

    Published on: 11 August 2017

  13. Research article

    The ethanol extract of Aquilariae Lignum ameliorates hippocampal oxidative stress in a repeated restraint stress mouse model

    Chronic stress contributes to the development of brain disorders, such as neurodegenerative and psychiatric diseases. Oxidative damage is well known as a causative factor for pathogenic process in brain tissue...

    Hyun-Yong Lee, Jin-Seok Lee, Hyeong-Geug Kim, Won-Yong Kim, Seung-Bae Lee, Yung-Hyun Choi and Chang-Gue Son

    BMC Complementary and Alternative Medicine 2017 17:397

    Published on: 10 August 2017

  14. Research article

    Flavonolignans inhibit the arachidonic acid pathway in blood platelets

    Arachidonic acid metabolism by cyclooxygenase (COX) is a major pathway for blood platelets’ activation, which is associated with pro-thrombotic platelet activity and the production of pro-inflammatory mediator...

    Michal Bijak and Joanna Saluk-Bijak

    BMC Complementary and Alternative Medicine 2017 17:396

    Published on: 10 August 2017

  15. Research article

    Combined antioxidant effects of Neem extract, bacteria, red blood cells and Lysozyme: possible relation to periodontal disease

    The common usage of chewing sticks prepared from Neem tree (Azadirachta indica) in India suggests its potential efficacy in periodontal diseases. The objective of this study is to explore the antibacterial effect...

    Leali Heyman, Yael Houri-Haddad, Samuel N. Heyman, Isaac Ginsburg, Yossi Gleitman and Osnat Feuerstein

    BMC Complementary and Alternative Medicine 2017 17:399

    Published on: 10 August 2017

  16. Research article

    Key stakeholder perspectives on the barriers and solutions to pharmacy practice towards complementary medicines: an Australian experience

    Although pharmacists are entrusted to play a role in ensuring the safe and appropriate use of all medicines, in general, the inclusion of complementary medicines (CMs) into their professional practice has not ...

    Carolina Oi Lam Ung, Joanna Harnett and Hao Hu

    BMC Complementary and Alternative Medicine 2017 17:394

    Published on: 9 August 2017

  17. Research article

    Aqueous extract of Phragmitis rhizoma ameliorates myelotoxicity of docetaxel in vitro and in vivo

    A variety of anticancer chemotherapeutics induce adverse side effects including myelotoxicity. Dried roots of Phragmites communis Trinius, Phragmitis rhizoma, have been clinically used in traditional folk medicin...

    Jinhee Kim, You Jin Lee, Young Ah Kim, Eun-Sang Cho, Eunna Huh, Ok-Sun Bang and No Soo Kim

    BMC Complementary and Alternative Medicine 2017 17:393

    Published on: 9 August 2017

  18. Research article

    [6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice

    [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is involved in insulin secretion and is perturbed in db/db ...

    Mehdi Bin Samad, Md. Nurul Absar Bin Mohsin, Bodiul Alam Razu, Mohammad Tashnim Hossain, Sinayat Mahzabeen, Naziat Unnoor, Ishrat Aklima Muna, Farjana Akhter, Ashraf Ul Kabir and J. M. A. Hannan

    BMC Complementary and Alternative Medicine 2017 17:395

    Published on: 9 August 2017

  19. Study protocol

    Evaluation of muscle activity, bite force and salivary cortisol in children with bruxism before and after low level laser applied to acupoints: study protocol for a randomised controlled trial

    Bruxism is a repetitive activity that causes tooth wear, audible sounds, and discomfort. Preventive measures have been studied for conditions that can exert a negative influence on physiological development in...

    Mônica da Consolação Canuto Salgueiro, Carolina Carvalho Bortoletto, Anna Carolina RattoTempestini Horliana, Ana Carolina Costa Mota, Lara Jansiski Motta, Pamella de Barros Motta, Raquel Agnelli MesquitaFerrari, Kristianne Porta Santos Fernandes and Sandra Kalil Bussadori

    BMC Complementary and Alternative Medicine 2017 17:391

    Published on: 8 August 2017

  20. Study protocol

    Study protocol on comparative effectiveness of mindfulness meditation and qigong on psychophysiological outcomes for patients with colorectal cancer: a randomized controlled trial

    Colorectal cancer imposes threats to patients’ well-being. Although most physical symptoms can be managed by medication, psychosocial stressors may complicate survival and hamper quality of life. Mindfulness a...

    Rainbow T. H. Ho, Adrian H. Y. Wan, Jessie S. M. Chan, S. M. Ng, K. F. Chung and Cecilia L. W. Chan

    BMC Complementary and Alternative Medicine 2017 17:390

    Published on: 8 August 2017

  21. Research article

    Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis

    The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereot...

    Patrick Amoateng, Samuel Adjei, Dorcas Osei-safo, Kennedy K. E. Kukuia, Emelia Oppong Bekoe, Thomas K. Karikari and Samuel B. Kombian

    BMC Complementary and Alternative Medicine 2017 17:389

    Published on: 7 August 2017

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