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  1. Content type: Research article

    Anacardium occidentale L phenolic lipid (LDT11) is used in traditional medicine as anti-inflammatory, astringent, antidiarrheal, anti-asthmatic and depurative. Phenolic derivatives, such as anacardic acid, extrac...

    Authors: Marilen Queiroz de Souza, Isabella Márcia Soares Nogueira Teotônio, Fernanda Coutinho de Almeida, Gabriella Simões Heyn, Priscilla Souza Alves, Luiz Antônio Soares Romeiro, Riccardo Pratesi, Yanna Karla de Medeiros Nóbrega and Claudia B. Pratesi

    Citation: BMC Complementary and Alternative Medicine 2018 18:181

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  2. Content type: Research article

    Oroxylum indicum (L.) Kurz (O. indicum) is found in Thailand. It has been used for the treatment of obesity. This study aimed to investigate the effects of an O. indicum extract (OIE) on the adipogenic and biomol...

    Authors: Tanaporn Hengpratom, Gordon M. Lowe, Kanjana Thumanu, Siriporn Suknasang, Kanokwan Tiamyom and Griangsak Eumkeb

    Citation: BMC Complementary and Alternative Medicine 2018 18:177

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  3. Content type: Research article

    Advanced hepatobiliary cancers are highly lethal cancers that require precise prediction in clinical practice. Serum ferritin level increases in malignancy and high serum ferritin level is associated with poor...

    Authors: Anna Song, Wankyu Eo, Sehyun Kim, Bumsang Shim and Sookyung Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:176

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  4. Content type: Correction

    Following publication of the original article [1], the authors reported that there was an error in the acknowledgements. In this Correction, the incorrect and correct acknowledgements are shown.

    Authors: Gulzar Ahmad Bhat, Haseeb A. Khan, Abdullah S. Alhomida, Poonam Sharma, Rambir Singh and Bilal Ahmad Paray

    Citation: BMC Complementary and Alternative Medicine 2018 18:175

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    The original article was published in BMC Complementary and Alternative Medicine 2018 18:162

  5. Content type: Research article

    In the view of endemic avian influenza H9N2 infection in poultry, its zoonotic potential and emergence of antiviral resistance, two herbal plants, Ocimum sanctum and Acacia arabica, which are easily available thr...

    Authors: S. S. Ghoke, R. Sood, N. Kumar, A. K. Pateriya, S. Bhatia, A. Mishra, R. Dixit, V. K. Singh, D. N. Desai, D. D. Kulkarni, U. Dimri and V. P. Singh

    Citation: BMC Complementary and Alternative Medicine 2018 18:174

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  6. Content type: Research article

    Trichilia catigua A. Juss. (Meliaceae) is a species known as catuaba and used in folk medicine for the treatment of fatigue, stress, impotence and memory deficit. The main phytochemical compounds identified in th...

    Authors: Nadini Oliveira Martins, Isabella Modelli de Brito, Sandra Syomara O. Araújo, Giuseppina Negri, Elisaldo de Araújo Carlini and Fúlvio Rieli Mendes

    Citation: BMC Complementary and Alternative Medicine 2018 18:172

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  7. Content type: Research article

    Bidens pilosa and Dichrostachys cinerea extracts were investigated for the antibacterial properties against waterborne diarrhoeagenic bacteria.

    Authors: Pfarelo Daphney Shandukani, Shonisani Cathphonia Tshidino, Peter Masoko and Kgabo Maureen Moganedi

    Citation: BMC Complementary and Alternative Medicine 2018 18:171

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  8. Content type: Research article

    The collapse of mitochondrial membrane potential (ΔΨm) resulted in the cell apoptosis and heart failure. Xinshuitong Capsule (XST) could ameliorate left ventricular ejection fraction (LVEF), New York Heart Ass...

    Authors: Chunjiang Tan, Jianwei Zeng, Yanbin Wu, Jiahui Zhang and Wenlie Chen

    Citation: BMC Complementary and Alternative Medicine 2018 18:170

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  9. Content type: Research article

    Biofilms have great significance in healthcare-associated infections owing to their inherent tolerance and resistance to antimicrobial therapies. New approaches to prevent and treat unwanted biofilms are urgen...

    Authors: Luca De Vincenti, Yvana Glasenapp, Cristina Cattò, Federica Villa, Francesca Cappitelli and Jutta Papenbrock

    Citation: BMC Complementary and Alternative Medicine 2018 18:168

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  10. Content type: Research article

    Combining conventional drugs and traditional medicine may represent a useful approach to combating antibiotic resistance, which has become a serious threat to global public health. This study aimed to evaluate...

    Authors: Weifeng Yang, Jueling Liu, Biljana Blažeković, Yanan Sun, Shuhua Ma, Chuanyun Ren, Sanda Vladimir-Knežević, Chaohua Li, Yajun Xing, Guijie Tian and Yi Wang

    Citation: BMC Complementary and Alternative Medicine 2018 18:169

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  11. Content type: Research article

    It is well known that Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by memory deficits and cognitive decline. Amyloid-β (Aβ) deposition and synaptic dysfunction play importa...

    Authors: Jing-Hua Zhang, Lin-Jie Yu, Hui Yang, Zhen Hui, Su Jiang, Ling Chen, Yang Zhao, Su-Lei Wang, Yi Liu and Yun Xu

    Citation: BMC Complementary and Alternative Medicine 2018 18:167

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  12. Content type: Research article

    The use of herbal medicines during pregnancy is very high globally and previous studies have pointed out possible associations with adverse pregnancy outcomes. Nevertheless, the safety of herbal medicines in p...

    Authors: Collins Zamawe, Carina King, Hannah Maria Jennings and Edward Fottrell

    Citation: BMC Complementary and Alternative Medicine 2018 18:166

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  13. Content type: Research article

    Propolis is multicomponent substance collected by honeybees from various plants. It is known for numerous biological effects and is commonly used as ethanolic extract because most of active substances of propo...

    Authors: Loreta Kubiliene, Aiste Jekabsone, Modestas Zilius, Sonata Trumbeckaite, Daiva Simanaviciute, Rima Gerbutaviciene and Daiva Majiene

    Citation: BMC Complementary and Alternative Medicine 2018 18:165

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  14. Content type: Research article

    Homoharringtonine (HHT) is a natural alkaloid with potent antitumor activity, but its precise mechanism of action is still poorly understood.

    Authors: Qi Sun, Shiyue Li, Junjun Li, Qiuxia Fu, Zhongyuan Wang, Bo Li, Shan-Shan Liu, Zijie Su, Jiaxing Song and Desheng Lu

    Citation: BMC Complementary and Alternative Medicine 2018 18:164

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  15. Content type: Research article

    There are increasing interests in natural compounds for cancer chemoprevention. Blocking agents represent an important class of chemopreventive compounds. They prevent carcinogens from undergoing metabolic act...

    Authors: Ali M. El-Halawany, Hossam M. Abdallah, Ahmed R. Hamed, Hany Ezzat Khalil and Ameen M. Almohammadi

    Citation: BMC Complementary and Alternative Medicine 2018 18:163

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  16. Content type: Research article

    Diabetes mellitus is one of the major global health disorders increasing at an alarming rate in both developed and developing countries. The objective of this study was to assess the effect of aqueous extract of

    Authors: Gulzar Ahmad Bhat, Haseeb A. Khan, Abdullah S. Alhomida, Poonam Sharma, Rambir Singh and Bilal Ahmad Paray

    Citation: BMC Complementary and Alternative Medicine 2018 18:162

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    The Correction to this article has been published in BMC Complementary and Alternative Medicine 2018 18:182

    The Correction to this article has been published in BMC Complementary and Alternative Medicine 2018 18:175

  17. Content type: Research article

    Ficus vasta Forssk. (Moraceae) is traditionally used for the treatment of various ailments; nonetheless, this species has been poorly studied to date. This work aimed to characterize the phenolic profile and to e...

    Authors: Maria Fernanda Taviano, Khaled Rashed, Angela Filocamo, Francesco Cacciola, Paola Dugo, Luigi Mondello, Carlo Bisignano, Rosaria Acquaviva, Manuela D’Arrigo and Natalizia Miceli

    Citation: BMC Complementary and Alternative Medicine 2018 18:161

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  18. Content type: Research article

    This present study sought to assess the modulatory effects of five Nigerian traditional polyherbal in high fructose-fed, streptozotocin-induced (HF-STZ) Type 2 diabetes (T2D) in rats. T2D was achieved via fruc...

    Authors: O. E. Kale, O. B. Akinpelu, A. A. Bakare, F. O. Yusuf, R. Gomba, D. C. Araka, T. O. Ogundare, A. C. Okolie, O. Adebawo and O. Odutola

    Citation: BMC Complementary and Alternative Medicine 2018 18:160

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  19. Content type: Research article

    Antimicrobial resistance is a serious threat against humankind and the search for new therapeutics is needed. This study aims to investigate the antimicrobial and antioxidant activities of ethanol extracts and...

    Authors: Raissa Tioyem Nzogong, Fabrice Sterling Tchantchou Ndjateu, Steve Endeguele Ekom, Jules-Arnaud Mboutchom Fosso, Maurice Ducret Awouafack, Mathieu Tene, Pierre Tane, Hiroyuki Morita, Muhammad Iqbal Choudhary and Jean-de-Dieu Tamokou

    Citation: BMC Complementary and Alternative Medicine 2018 18:159

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  20. Content type: Research article

    Complementary and alternative medicines (CAM) are sometimes used by individuals who desire to improve the outcomes of their fertility treatment and/or mental health during fertility treatment. However, there i...

    Authors: Skye A. Miner, Stephanie Robins, Yu Jia Zhu, Kathelijne Keeren, Vivian Gu, Suzanne C. Read and Phyllis Zelkowitz

    Citation: BMC Complementary and Alternative Medicine 2018 18:158

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  21. Content type: Study protocol

    Knee Osteoarthritis (KOA) is a very common condition with prevalence rising with age. It is a major contributor to global disability and has a large socioeconomic burden worldwide. Conservative therapies have ...

    Authors: Regina Wing Shan Sit, Ricky Wing Keung Wu, Kenneth Dean Reeves, David Rabago, Dicken Cheong Chun Chan, Benjamin Hon Kei Yip, Vincent Chi Ho Chung and Samuel Yeung Shan Wong

    Citation: BMC Complementary and Alternative Medicine 2018 18:157

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  22. Content type: Research article

    Oxidative stress and renal apoptosis play a significant role in the progression of diabetic nephropathy. The tubers of Pueraria tuberosa (Roxb. ex Willd.) DC. has been traditionally used as anti-ageing and health...

    Authors: Rashmi Shukla, Somanshu Banerjee and Yamini B. Tripathi

    Citation: BMC Complementary and Alternative Medicine 2018 18:156

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  23. Content type: Research article

    Few studies have investigated the prevalence and characteristics of potentially inappropriate Kampo medication use among elderly ambulatory patients taking any prescribed Kampo medications.

    Authors: Junpei Komagamine and Kazuhiko Hagane

    Citation: BMC Complementary and Alternative Medicine 2018 18:155

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  24. Content type: Research article

    Since oxidative stress and inflammation are two linked factors in the pathogenesis of several human diseases. Thus identification of effective treatment is of great importance. Edible mushroom and microalgae a...

    Authors: Marwa M. Abu-Serie, Noha H. Habashy and Wafaa E. Attia

    Citation: BMC Complementary and Alternative Medicine 2018 18:154

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  25. Content type: Research article

    The significant use of traditional and complementary medicine (T&CM) by cancer survivors is well documented. The aim of this study was to explore cancer survivors’ views on integrating T&CM services with conve...

    Authors: Jennifer Hunter, Jane Ussher, Chloe Parton, Andrew Kellett, Caroline Smith, Geoff Delaney and Eleanor Oyston

    Citation: BMC Complementary and Alternative Medicine 2018 18:153

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  26. Content type: Research article

    Breast cancer is the most common cancer in women and affects 1.38 million women worldwide per year. Antiestrogens such as tamoxifen, a selective estrogen receptor (ER) modulator, are widely used in clinics to ...

    Authors: Yu-Shih Lin, Yin-Yin Lin, Yao-Hsu Yang, Chun-Liang Lin, Feng-Che Kuan, Cheng-Nan Lu, Geng-He Chang, Ming-Shao Tsai, Cheng-Ming Hsu, Reming-Albert Yeh, Pei-Rung Yang, I-Yun Lee, Li-Hsin Shu, Yu-Ching Cheng, Hung-Te Liu, Kuan-Der Lee…

    Citation: BMC Complementary and Alternative Medicine 2018 18:152

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  27. Content type: Research article

    Dental caries remains a serious problem due to its detrimental effects on individual health and quality of life. The bulbs of Myrmecodia pendans (Merr & Perry), native plants of Papua, have been used as natural r...

    Authors: Meirina Gartika, Hening T. Pramesti, Dikdik Kurnia and Mieke H. Satari

    Citation: BMC Complementary and Alternative Medicine 2018 18:151

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  28. Content type: Research article

    Sheng Jiang San (SJS), a multi-herb formulation, is used in treating high fever, thirsty and anxiety in ancient China and it is sometimes used to treat seasonal influenza nowadays. However, there is no evidenc...

    Authors: Tianbo Zhang, Mengjie Xiao, Chun-Kwok Wong, Ka-Pun Chris Mok, Xin Zhao, Huihui Ti and Pang-Chui Shaw

    Citation: BMC Complementary and Alternative Medicine 2018 18:150

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  29. Content type: Research article

    The potential toxicity of Chinese herbal medicine has attracted more attention in recent years. Jueyin granules (JYG), a polyherbal formula, have been proven to be an effective agent for treating psoriasis in bot...

    Authors: Yu Chen, Dong-jie Guo, Hui Deng, Min-feng Wu, Ya-Nan Zhang, Su Li, Rong Xu, Jie Chen, Xing-xiu Jin, Bin Li, Qi Xu and Fu-lun Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:148

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  30. Content type: Research article

    Natural product is one of the most important sources of drugs used in pharmaceutical therapeutics. Artemisia capillaris has been traditionally used as a hepatoprotective and anti-inflammatory agent. In this study...

    Authors: Juyoung Kim, Kyung Hee Jung, Hong Hua Yan, Min Ji Cheon, Sunmi Kang, Xing Jin, Sunghyouk Park, Myung Sook Oh and Soon-Sun Hong

    Citation: BMC Complementary and Alternative Medicine 2018 18:147

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  31. Content type: Research article

    Human placenta hydrolysate (hPH) has been utilized to improve menopausal, fatigue, liver function. Its high concentration of bioactive substances is known to produce including antioxidant, anti-inflammatory an...

    Authors: Hyun-Jung Park, Hyun Soo Shim, Sunyoung Lee, Dae Hyun Hahm, Hyejung Lee, Chang Taek Oh, Hae Jung Han, Hyi Jeong Ji and Insop Shim

    Citation: BMC Complementary and Alternative Medicine 2018 18:149

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  32. Content type: Research article

    Fine particulate matter (PM2.5) is a major risk factor for the development and progression of atherosclerosis. Proliferation and infiltration of vascular smooth muscle cells (VSMCs) from the blood vessel media...

    Authors: Qiang Wan, Zhongyong Liu and Yuping Yang

    Citation: BMC Complementary and Alternative Medicine 2018 18:146

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  33. Content type: Research article

    Cryptococcal infections, besides being a problem for immunocompromised patients, are occasionally being a problem for immunocompetent patients. In addition, the lower susceptibility of this yeast to azoles is ...

    Authors: Daniela Scalas, Narcisa Mandras, Janira Roana, Roberta Tardugno, Anna Maria Cuffini, Valeria Ghisetti, Stefania Benvenuti and Vivian Tullio

    Citation: BMC Complementary and Alternative Medicine 2018 18:143

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  34. Content type: Research article

    Propolis, a polyphenol-rich natural product, has been used as a functional food in anti-inflammation. However, its bioactive components and mechanisms have not been fully elucidated.

    Authors: Huasong Chang, Wenwen Yuan, Haizhu Wu, Xusheng Yin and Hongzhuan Xuan

    Citation: BMC Complementary and Alternative Medicine 2018 18:142

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  35. Content type: Research article

    In a former meta-analysis review, acupuncture was considered a potentially effective treatment for dry eye syndrome (DES), but there were heterogeneities among the outcomes. We updated the meta-analysis and co...

    Authors: Bong Hyun Kim, Min Hee Kim, Se Hyun Kang and Hae Jeong Nam

    Citation: BMC Complementary and Alternative Medicine 2018 18:145

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  36. Content type: Research article

    The current treatment for human brucellosis requires a combination of antibiotics for long periods of time, and the reported incidence and prevalence of the disease vary widely in nomadic livestock of Mongolia...

    Authors: Tsevelmaa N, Narangerel B, Odgerel O, Dariimaa D and Batkhuu J

    Citation: BMC Complementary and Alternative Medicine 2018 18:144

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  37. Content type: Research article

    Terminalia chebula Retz. (Combretaceae) is a traditional herbal medicine that is widely used in the treatment of diabetes, immunodeficiency diseases, and stomach ulcer in Asia. However, the anti-amnesic effect of...

    Authors: Min-Soo Kim, Dong Young Lee, Jun Lee, Hyun Woo Kim, Sang Hyun Sung, Jung-Soo Han and Won Kyung Jeon

    Citation: BMC Complementary and Alternative Medicine 2018 18:136

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  38. Content type: Research article

    Cancer patients often suffer from emotional distress as a result of the oncological process. The purpose of our study was to determine whether practice of Jacobson’s relaxation technique reduced consumption of...

    Authors: Paula Parás-Bravo, Cristina Alonso-Blanco, María Paz-Zulueta, Domingo Palacios-Ceña, Carmen María Sarabia-Cobo, Manuel Herrero-Montes, Ester Boixadera-Planas and César Fernández-de-las-Peñas

    Citation: BMC Complementary and Alternative Medicine 2018 18:139

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  39. Content type: Research article

    Brazilian green propolis is produced by mixing secretions from Africanized honey bees with exudate, mainly from Baccharis dracunculifolia. Brazilian propolis is especially rich in flavonoids and cinammic acid der...

    Authors: Hiroshi Kitamura, Natsuko Saito, Junpei Fujimoto, Ken-ichi Nakashima and Daisuke Fujikura

    Citation: BMC Complementary and Alternative Medicine 2018 18:138

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  40. Content type: Research article

    Solanum aculeastrum fruits are used by some cancer sufferers as a form of alternative treatment. Scientific literature is scarce concerning its anticancer activity, and thus the aim of the study was to assess the...

    Authors: Trevor Burger, Tsholofelo Mokoka, Gerda Fouché, Paul Steenkamp, Vanessa Steenkamp and Werner Cordier

    Citation: BMC Complementary and Alternative Medicine 2018 18:137

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  41. Content type: Research article

    Herba Siegesbeckiae (HS, Xixiancao in Chinese) is a commonly used traditional Chinese medicinal herb for soothing joints. In ancient materia medica books, HS is recorded to be the aerial part of Siegesbeckia pube...

    Authors: Hui Guo, Yi Zhang, Brian Chi-Yan Cheng, Mei-Yuk Lau, Xiu-Qiong Fu, Ting Li, Tao Su, Pei-Li Zhu, Yuen-Cheung Chan, Anfernee Kai-Wing Tse, Tao Yi, Hu-Biao Chen and Zhi-Ling Yu

    Citation: BMC Complementary and Alternative Medicine 2018 18:141

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  42. Content type: Research article

    Medicinal plants have been founded as traditional herbal medicine worldwide. Most of the plant’s therapeutic properties are due to the presence of secondary metabolites such as alkaloids, glycosides, tannins a...

    Authors: Hazir Rahman, Ilyas Khan, Anwar Hussain, Abdelaaty Abdelaziz Shahat, Abdul Tawab, Muhammad Qasim, Muhammad Adnan, Mansour S. Al-Said, Riaz Ullah and Shahid Niaz Khan

    Citation: BMC Complementary and Alternative Medicine 2018 18:140

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  43. Content type: Research article

    Schistosomiasis is an acute and chronic zoonotic parasitic disease caused by trematode worms. The host inflammatory response to schistosome eggs leads to perioval granulomata formation, mainly in the liver and...

    Authors: Dina M. Metwally, Ebtesam M. Al-Olayan, Mohammad Alanazi, Sanaa B. Alzahrany and Abdelhabib Semlali

    Citation: BMC Complementary and Alternative Medicine 2018 18:135

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  44. Content type: Research article

    Radix Paeoniae Rubra (RPR), a traditional Chinese herb, has anti-inflammatory and immuno-regulatory properties. This study explored the effects of RPR on stimulation of osteoclast differentiation in RAW264.7 c...

    Authors: Huey-En Tzeng, Chun-Hao Tsai, Tin-Yun Ho, Chin-Tung Hsieh, Shen-Chieh Chou, Yi-Ju Lee, Gregory J. Tsay, Po-Hao Huang and Yi-Ying Wu

    Citation: BMC Complementary and Alternative Medicine 2018 18:132

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  45. Content type: Study protocol

    Sinew acupuncture is a new modality of acupuncture in which needles are inserted into acupoints, ashi points or spasm points of sinew and muscles along the meridian sinew pathway. A previous observational stud...

    Authors: Kwok Yin Au, Haiyong Chen, Wing Chung Lam, Chiu On Chong, Andrew Lau, Varut Vardhanabhuti, Kin Cheung Mak, Fei Jiang, Wing Yi Lam, Fung Man Wu, Hiu Ngok Chan, Yan Wah Ng, Bacon Fung-Leung Ng, Eric Tat-Chi Ziea and Lixing Lao

    Citation: BMC Complementary and Alternative Medicine 2018 18:133

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  46. Content type: Research article

    The medicinal orchid Dendrobium moniliforme contains water-soluble polysaccharides, phenanthrenes, bibenzyl derivatives, and polyphenol compounds. This study explored the antioxidant and cytotoxic activities of D...

    Authors: Mukti Ram Paudel, Mukesh Babu Chand, Basant Pant and Bijaya Pant

    Citation: BMC Complementary and Alternative Medicine 2018 18:134

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  47. Content type: Research article

    Previously, we reported that ChondorT showed significant anti-arthritis and anti-inflammatory effects. ChondroT, a new herbal medication, consists of the water extracts of Osterici Radix, Lonicerae Folium, Angeli...

    Authors: Jiwon Jeong, Kiljoon Bae, Sun-Gil Kim, Dongwook Kwak, Young-Joo Moon, Chan-Hun Choi, Young-Ran Kim, Chang-Su Na and Seon-Jong Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:131

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  48. Content type: Research article

    There is limited research regarding patients’ profiles and consumer attitudes and habits of osteopathy in Spain. The purpose of this study was to profile patients who regularly receive osteopathic care in Spai...

    Authors: Gerard Alvarez Bustins, Pedro-Victor López Plaza and Sonia Roura Carvajal

    Citation: BMC Complementary and Alternative Medicine 2018 18:129

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  49. Content type: Research article

    Houttuynia cordata Thunb. and Phyllanthus emblica Linn. are native plants with medicinal and nutritive significance in Asia. The present study was aimed at evaluating antiproliferative effects on human cancer cel...

    Authors: Piyawan Kumnerdkhonkaen, Somprasong Saenglee, Md. Ali Asgar, Gulsiri Senawong, Kanoknan Khongsukwiwat and Thanaset Senawong

    Citation: BMC Complementary and Alternative Medicine 2018 18:130

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