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  1. Content type: Research article

    Tuberculosis is a deadly disease caused by Mycobacterium species. The use of medicinal plants is an ancient global practice for the treatment and prevention of diverse ailments including tuberculosis. The aim of ...

    Authors: Abimbola O. Aro, Jean P. Dzoyem, Maurice D. Awouafack, Mamoalosi A. Selepe, Jacobus N. Eloff and Lyndy J. McGaw

    Citation: BMC Complementary and Alternative Medicine 2019 19:108

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  2. Content type: Research article

    The therapeutic use of Helleborus niger L. is manifold due to its specific phytochemical composition. Two compound groups, the ranunculin derivates including protoanemonin and the steroidal saponins, are also ass...

    Authors: Jennifer E. Felenda, Claudia Turek, Nora Mörbt, Anja Herrick, Margit B. Müller and Florian C. Stintzing

    Citation: BMC Complementary and Alternative Medicine 2019 19:105

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  3. Content type: Research article

    Despite advances in medical treatments, the proportion of the population suffering from alopecia is increasing, creating a need for new treatments to control hair loss and prevent balding. Treatments based on ...

    Authors: Gun-He Nam, Kyung-Jo Jo, Ye-Seul Park, Hye Won Kawk, Je-Geun Yoo, Jin Dong Jang, Sang Moon Kang, Sang-Yong Kim and Young-Min Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:104

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  4. Content type: Research article

    Chinese herbal bath therapy (CHBT) is a traditional external therapy that has been used for the treatment of uremic pruritus (UP) in China. We conducted a meta-analysis to evaluate the efficacy and safety of C...

    Authors: Wenxuan Xue, Yanhua Zhao, Mengyun Yuan and Zhiqiang Zhao

    Citation: BMC Complementary and Alternative Medicine 2019 19:103

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  5. Content type: Research article

    Calothamnus quadrifidus R.Br has many traditional uses and there are few reports about its chemical and biological activities. So our aim is to isolate the triterpenoidal compounds from dichloromethane fraction (...

    Authors: H. A. Ibrahim, M. R. Elgindi, R. R. Ibrahim and D. G. El-Hosari

    Citation: BMC Complementary and Alternative Medicine 2019 19:102

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  6. Content type: Research article

    Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated. In the present study, ...

    Authors: Ji Min Shin, Kyung-Mi Lee, Hee Ju Lee, Ji Ho Yun and Chu Won Nho

    Citation: BMC Complementary and Alternative Medicine 2019 19:101

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  7. Content type: Research article

    Obesity is a risk factor for many diseases including diabetes, cancer, arthritis, and cardiovascular diseases. Angiogenesis nourishes adipose tissues and contributes to obesity; it can be prevented by suppress...

    Authors: Muhammad Imran Khan, Jin Hyuk Shin and Jong Deog Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:100

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  8. Content type: Research article

    Type 2 diabetes (T2D) is a global pandemic, and contributes significantly to the increasing incidence of conditions such as cardiovascular disease (CVD). Postprandial plasma glucose measured 2-h after the star...

    Authors: Ratheesh Mohan, Svenia Jose, Johannah Mulakkal, Darla Karpinsky-Semper, Andrew G. Swick and I. M. Krishnakumar

    Citation: BMC Complementary and Alternative Medicine 2019 19:99

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  9. Content type: Research article

    Current therapeutic approaches to treat metastatic breast cancer, although effective, have shown many inadvertent side effects such as genotoxicity due to a lack of selectivity. Thus, these treatment plans are...

    Authors: Christopher Nguyen, Kiruthika Baskaran, Alaina Pupulin, Ivan Ruvinov, Ola Zaitoon, Sahibjot Grewal, Benjamin Scaria, Ali Mehaidli, Caleb Vegh and Siyaram Pandey

    Citation: BMC Complementary and Alternative Medicine 2019 19:98

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  10. Content type: Research article

    Endothelial dysfunction (ED) has been observed in individuals with metabolic syndrome (MetS) and contributes to the initiation and progression of atherosclerosis. The primary management of MetS involves lifest...

    Authors: Pingali Usharani, Padma Latha Merugu and Chandrasekhar Nutalapati

    Citation: BMC Complementary and Alternative Medicine 2019 19:97

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  11. Content type: Research article

    The purpose of this pilot study was to determine if a definitive clinical trial of thiamine supplementation was warranted in patients with acute heart failure. We hypothesized that thiamine, when added to stan...

    Authors: Howard A. Smithline, Michael Donnino, Fidela S. J. Blank, Richard Barus, Ryan A. Coute, Alexander B. Knee and Paul Visintainer

    Citation: BMC Complementary and Alternative Medicine 2019 19:96

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  12. Content type: Research article

    Traditional medicine has always been Pakistan’s cultural heritage, providing health care to a large part of its population. Thus, we aimed to assess and compare the knowledge, attitude, and perception about co...

    Authors: Mariam Ashraf, Hamid Saeed, Zikria Saleem, Hassaan Anwer Rathore, Fawad Rasool, Eman Tahir, Tooba Bhatti, Javeria Khalid, Iqra Bhatti and Ayesha Tariq

    Citation: BMC Complementary and Alternative Medicine 2019 19:95

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  13. Content type: Research article

    The brain is susceptible to methylmercury toxicity, which causes irreversible damage to neurons and glia and the leaf extract Dendropanax morbifera Léveille (DML) has various biological functions in the nervous s...

    Authors: Woosuk Kim, Dae Young Yoo, Hyo Young Jung, Jong Whi Kim, Kyu Ri Hahn, Hyun Jung Kwon, Miyoung Yoo, Sanghee Lee, Sung Min Nam, Yeo Sung Yoon, Dae Won Kim and In Koo Hwang

    Citation: BMC Complementary and Alternative Medicine 2019 19:94

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  14. Content type: Research article

    Complementary and alternative medicine (CAM) is a rather novel issue within public healthcare and health policy-making. CAM use in Europe is widespread, patient-initiated, and patient-evaluated, and the regula...

    Authors: Anita Salamonsen and Solveig Wiesener

    Citation: BMC Complementary and Alternative Medicine 2019 19:93

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  15. Content type: Research article

    To investigate the effects of the Alisma and Rhizoma decoction on nonalcoholic steatohepatitis (NASH) and to further shed light on the underlying mechanisms of the actions of the Alisma and Rhizoma decoction.

    Authors: Lijun Xu, Menghui Jing, Lijuan Yang, Lei Jin, Peiqiang Gong, Juan Lu, Hui Lin, Jinping Wang, Qin Cao and Yuanye Jiang

    Citation: BMC Complementary and Alternative Medicine 2019 19:92

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  16. Content type: Research article

    The extract of Celastrus orbiculatus (COE) have been studied for anti-Helicobacter pylori (H. pylori) activity and anti-cancer effects in vitro and in vivo. However, the molecular mechanism by which COE inhibits

    Authors: Yaodong Zhu, Lei Liu, Lei Hu, Wenqing Dong, Mei Zhang, Yanqing Liu and Ping Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:91

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  17. Content type: Research article

    Papaver nudicaule belongs to the Papaveraceae family, which is planted as an annual herbaceous species generally for ornamental purpose. Papaver rhoeas in the same family has been reported to have various pharmac...

    Authors: Jae-Hyeon Oh, Miyong Yun, Dain Park, In Jin Ha, Chang-Kug Kim, Do-Wan Kim, Eun-Ok Kim and Seok-Geun Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:90

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  18. Content type: Research article

    Rubus coreanus fruit (RF) has been used as a traditional medicine formulation to treat various diseases including diarrhea, asthma, and cancer in East Asia (Korea, China, and Japan). RF, which is native to Korea,...

    Authors: Kyung Hye Seo, Ji Yeon Lee, Jeong-Yong Park, Gwi Yeong Jang, Hyung Don Kim, Young- Seob Lee and Dong Hwi Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:89

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  19. Content type: Research article

    Stevia rebaudiana Bertoni has various pharmacological actions, which includes antidiabetic, antioxidant, anti-inflammatory activities. The superoxide and consequently NADPH oxidase (Nox) are relevant targets invo...

    Authors: A. S. Isoyan, K. V. Simonyan, R. M. Simonyan, M. A. Babayan, G. M. Simonyan, V. A. Chavushyan and M. A. Simonyan

    Citation: BMC Complementary and Alternative Medicine 2019 19:88

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  20. Content type: Research article

    Whole-body electrical myostimulation (WB-EMS) is a relatively recent training methodology that has been extraordinarily used in recent years. However, there is a lack of consensus on the effectiveness of WB-EM...

    Authors: Alvaro Pano-Rodriguez, Jose Vicente Beltran-Garrido, Vicenç Hernández-González and Joaquim Reverter-Masia

    Citation: BMC Complementary and Alternative Medicine 2019 19:87

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  21. Content type: Research article

    The modified Si-Jun-Zi Decoction (SJZ), a Chinese medicine formula, is clinically used against multiple malignancies including colorectal cancer (CRC). This study aims to evaluate the effect of modified SJZ on...

    Authors: Jin-Yong Zhou, Min Chen, Cun-En Wu, Yu-Wen Zhuang, Yu-Gen Chen and Shen-Lin Liu

    Citation: BMC Complementary and Alternative Medicine 2019 19:86

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  22. Content type: Research article

    In 2011 there was a strengthening of European Union (EU) legislation on the licencing of herbal products which, in the UK, resulted in the introduction of the Traditional Herbal Registration (THR) scheme. This...

    Authors: R. Dickinson, M. C. Kennedy, D. K. Raynor, P. Knapp, M. Thomas and E. Adami

    Citation: BMC Complementary and Alternative Medicine 2019 19:85

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  23. Content type: Case report

    Fructus Psoraleae is the seed of Psoralea corylifolia Linn. Fructus Psoraleae has been shown to be effective in treating some skin diseases, such as vitiligo. As a main ingredient in five types of herbs in the Qu...

    Authors: Ang Li, Minhong Gao, Na Zhao, Ping Li, Jinguo Zhu and Wenfei Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:84

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  24. Content type: Research article

    Integrative and complementary health approaches (ICHA) are often pursued by patients facing chronic illnesses. Most of the studies that investigated the factors associated with ICHA consumption have considered...

    Authors: Fabrice Berna, Anja S. Göritz, Amaury Mengin, Renaud Evrard, Jacques Kopferschmitt and Steffen Moritz

    Citation: BMC Complementary and Alternative Medicine 2019 19:83

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  25. Content type: Research article

    Cytinus is small genus of endophytic parasitic plants distributed in South Africa, Madagascar, and in the Mediterranean region. In the latter area, two species occur, Cytinus hypocistis and C. ruber, distinguishe...

    Authors: Giuseppantonio Maisetta, Giovanna Batoni, Pierluigi Caboni, Semih Esin, Andrea C. Rinaldi and Paolo Zucca

    Citation: BMC Complementary and Alternative Medicine 2019 19:82

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  26. Content type: Research article

    Diabetic nephropathy (DN) is a common complication of diabetes mellitus (DM) that imposes an enormous burden on the healthcare system. Although some studies show that traditional Chinese medicine (TCM) treatme...

    Authors: Hsing-Yu Chen, Heng-Chih Pan, Yung-Chang Chen, Yu-Chun Chen, Yi-Hsuan Lin, Sien-Hung Yang, Jiun-Liang Chen and Hau-Tieng Wu

    Citation: BMC Complementary and Alternative Medicine 2019 19:81

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  27. Content type: Research article

    Organochalcogen compounds have attracted the interest of a multitude of studies for their promising Pharmacological and biological activities. The antioxidant activity and acute toxicity of an organoselenium c...

    Authors: Mohammad Ibrahim, Niaz Muhammad, Musadiq Ibrahim, Muhammad Idrees Khan, Muhammad Ishaq Ali Shah, Muhammad Said, Waliullah Khan, Jean Paul Kamdem and Joao Batista Teixeira Rocha

    Citation: BMC Complementary and Alternative Medicine 2019 19:80

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  28. Content type: Research article

    Methanol extract (MECN) of Clinacanthus nutans Lindau leaves (family Acanthaceae) demonstrated peripherally and centrally mediated antinociceptive activity via the modulation of opioid/NO-mediated, but cGMP-indep...

    Authors: Zainul Amiruddin Zakaria, Mohammad Hafiz Abdul Rahim, Mohd Hijaz Mohd Sani, Maizatul Hasyima Omar, Siew Mooi Ching, Arifah Abdul Kadir and Qamar Uddin Ahmed

    Citation: BMC Complementary and Alternative Medicine 2019 19:79

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  29. Content type: Research article

    Teaching Complementary and alternative medicine (CAM) in medical schools is becoming prevalent worldwide. Few studies have been conducted to evaluate medical students’ knowledge and attitude toward CAM. Theref...

    Authors: Ahmad M. Samara, Ethar R. Barabra, Hala N. Quzaih and Sa’ed H. Zyoud

    Citation: BMC Complementary and Alternative Medicine 2019 19:78

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  30. Content type: Research article

    Cordyceps is a traditional Chinese herb that produces various biopharmaceutical effects, including immune-enhancing effects. In this study, we prepared a Cordyceps mycelium culture extract (Paecilomyces hepiali, ...

    Authors: Su-Jin Jung, Eun-Soo Jung, Eun-Kyung Choi, Hong-Sig Sin, Ki-Chan Ha and Soo-Wan Chae

    Citation: BMC Complementary and Alternative Medicine 2019 19:77

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  31. Content type: Research article

    Music has been shown to improve health and quality of life. It was suggested that music may also have an impact on gait stability and fall risk. Yet, few studies have exploited music in the hospital setting, a...

    Authors: Julia Chabot, Olivier Beauchet, Shek Fung and Isabelle Peretz

    Citation: BMC Complementary and Alternative Medicine 2019 19:76

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  32. Content type: Research article

    The introduction of imatinib revolutionized the treatment of chronic myeloid leukaemia (CML), substantially extending patient survival. However, imatinib resistance is currently a clinical problem for CML. It ...

    Authors: Huayao Li, Lijuan Liu, Jing Zhuang, Cun Liu, Chao Zhou, Jing Yang, Chundi Gao, Gongxi Liu and Changgang Sun

    Citation: BMC Complementary and Alternative Medicine 2019 19:75

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  33. Content type: Research article

    Different plant parts of Roylea cinerea (D. Don) Baill. (Lamiaceae), Clematis grata Wall. (Ranunculaceae), Cornus capitata Wall. (Cornaceae) are traditionally used in the management of diabetes and various other ...

    Authors: Astha Bhatia, Balbir Singh, Rohit Arora and Saroj Arora

    Citation: BMC Complementary and Alternative Medicine 2019 19:74

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  34. Content type: Research article

    Complementary Medicine (CM) continues to thrive across many countries. Closely related to the continuing popularity of CM has been an increased number of enrolments at CM education institutions across the publ...

    Authors: Alastair C. Gray, Amie Steel and Jon Adams

    Citation: BMC Complementary and Alternative Medicine 2019 19:73

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  35. Content type: Research article

    Solidago chilensis (syn. microglossa) is a plant from the Asteraceae family widely distributed in South America and used to treat inflammatory diseases. In 2009, it was listed as one of the native medicinal herba...

    Authors: Elena L. A. Malpezzi-Marinho, Graziela R. Molska, Lyvia I. G. P. Freire, Cristiane I. Silva, Eduardo K. Tamura, Laís F. Berro, Carlos A. Parada and Eduardo Ary Villela Marinho

    Citation: BMC Complementary and Alternative Medicine 2019 19:72

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  36. Content type: Research article

    Ocimum gratissimum L. is a medicinal plant widely grown in tropical and subtropical regions with the leaf decoction usually taken in folk medicine to enhance erectile performance in men although the probable mech...

    Authors: Oluwafemi Adeleke Ojo, Adebola Busola Ojo, Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Omosola Olufisayo Anifowose, Ayodeji Akawa, Oluranti Esther Olaiya, Oluwaseun Ruth Olasehinde and Abidemi Paul Kappo

    Citation: BMC Complementary and Alternative Medicine 2019 19:71

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  37. Content type: Research article

    Influenza is a common viral infection worldwide. Maoto (ma-huang-tang) was developed in ancient China and is used to alleviate flu symptoms. Currently, no meta-analyses have evaluated the efficacy and safety of m...

    Authors: Tetsuhiro Yoshino, Ryutaro Arita, Yuko Horiba and Kenji Watanabe

    Citation: BMC Complementary and Alternative Medicine 2019 19:68

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  38. Content type: Research article

    Epithelial-mesenchymal transition (EMT) is a vital process in cancer progression and metastasis. Yanggan Jiedu Sanjie (YGJDSJ) is Traditional Chinese Medicine formulation for liver cancer treatment. In the pre...

    Authors: Bing Hu, Hong-Mei An, Xia Yan, Jia-Lu Zheng, Xiao-Wei Huang and Miao Li

    Citation: BMC Complementary and Alternative Medicine 2019 19:67

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  39. Content type: Research article

    The use of medications, including herbal medicines during breastfeeding is always a concern among women. Currently, there is no published evidence on whether Sierra Leonean women use herbal medicine during bre...

    Authors: Peter Bai James, Angela Isata Kaikai, Abdulai Jawo Bah, Amie Steel and Jon Wardle

    Citation: BMC Complementary and Alternative Medicine 2019 19:66

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  40. Content type: Research article

    Herbal medicine has become the panacea for many rural pregnant women in Ghana despite the modern western antenatal care which has developed in most parts of the country. To our knowledge, previous studies inve...

    Authors: Prince Peprah, Williams Agyemang-Duah, Francis Arthur-Holmes, Hayford Isaac Budu, Emmanuel Mawuli Abalo, Reforce Okwei and Julius Nyonyo

    Citation: BMC Complementary and Alternative Medicine 2019 19:65

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  41. Content type: Research article

    We investigated the effects of a berry mixture formula (modified Ojayeonjonghwan (Wuzi Yanzong Wan, MO formula) on detrusor overactivity (DO).

    Authors: Sangrak Bae, Kyu Won Lee, Hyun Cheol Jeong, Bong Hee Park, Woong Jin Bae, Chang Hee Han and Sae Woong Kim

    Citation: BMC Complementary and Alternative Medicine 2019 19:64

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  42. Content type: Research article

    Physical activity is an important part of the diabetes management plan. However, the effects caused by different training durations and styles of Tai Chi have not been evaluated. We conducted an updated system...

    Authors: Ting-Wei Xia, Yue Yang, Wei-Hong Li, Zhao-Hui Tang, Zong-Run Li and Li-Jun Qiao

    Citation: BMC Complementary and Alternative Medicine 2019 19:63

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  43. Content type: Research article

    Access to and advice on Complementary and Alternative Medicine (CAM) are uncommon within Swedish conventional cancer care and little is known about cancer patients’ own use of CAM. The aim of this cross-sectio...

    Authors: Kathrin Wode, Roger Henriksson, Lena Sharp, Anna Stoltenberg and Johanna Hök Nordberg

    Citation: BMC Complementary and Alternative Medicine 2019 19:62

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  44. Content type: Research article

    This systematic review evaluates the use of manual therapy for clinical conditions in the pediatric population, assesses the methodological quality of the studies found, and synthesizes findings based on healt...

    Authors: Carol Parnell Prevost, Brian Gleberzon, Beth Carleo, Kristian Anderson, Morgan Cark and Katherine A. Pohlman

    Citation: BMC Complementary and Alternative Medicine 2019 19:60

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  45. Content type: Study protocol

    Practitioners of complementary and alternative medicine have suggested that acupuncture could alleviate poststroke shoulder pain, based on the clinical evidence. This study protocol is aimed at showing the eff...

    Authors: Seungwon Shin, Sung Pil Yang, Ami Yu, Junghee Yoo, Sung Min Lim and Euiju Lee

    Citation: BMC Complementary and Alternative Medicine 2019 19:58

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  46. Content type: Research article

    Prolonged hyperuricemia is associated with kidney disease or gouty arthritis. Whether Yokuininto, a commercially available Kampo medicine that has been used for osteoarthritis or rheumatoid arthritis, can exhi...

    Authors: Seung Hoon Lee, Ho-Sung Lee, Gunhyuk Park, Sung-Man Oh and Dal-Seok Oh

    Citation: BMC Complementary and Alternative Medicine 2019 19:57

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