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BMC Complementary and Alternative Medicine

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Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    Solanum nigrum, herbal plant that commonly grows in temperate climate zone, has been used as a traditional folk medicine whose ripen fruits were proven to exhibit anti-tumor properties...

    Authors: Sankar Jagadeeshan, Diana David, S. Jisha, S. Manjula and S. Asha Nair

    Citation: BMC Complementary and Alternative Medicine 2017 17:370

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  2. Content type: Research article

    Beta-mangostin (BM) is a xanthone-type of natural compound isolated from Cratoxylum arborescens. This study aimed to examine the apoptosis mechanisms induced by BM in a murine monomyelocytic cell line (WEHI-3) in...

    Authors: Fatima Abdelmutaal Ahmed Omer, Najihah Mohd Hashim, Mohamed Yousif Ibrahim, Abdulmannan F. Aldoubi, Pouya Hassandarvish, Firouzeh Dehghan, Noraziah Nordin, Hamed Karimian, Landa Zeenelabdin Ali Salim, Mahmood Ameen Abdulla, Karim Al-Jashamy and Syam Mohan

    Citation: BMC Complementary and Alternative Medicine 2017 17:366

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  3. Content type: Research article

    In this study, Aloe vera samples were collected from different climatic regions of India. Quantitative HPTLC (high performance thin layer chromatography) analysis of important anthraquinones aloin and aloe-emodin...

    Authors: Sandeep Kumar, Manila Yadav, Amita Yadav, Pooja Rohilla and Jaya Parkash Yadav

    Citation: BMC Complementary and Alternative Medicine 2017 17:369

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  4. Content type: Research article

    Curcuma longa L. is a well-known medicinal plant that has been used for its anti-cancer, neuroprotective, and hepatoprotective effects. However, the neuroprotective effect of fermented...

    Authors: Cheong-Su Eun, Jong-Soon Lim, Jihye Lee, Sam-Pin Lee and Seun-Ah Yang

    Citation: BMC Complementary and Alternative Medicine 2017 17:367

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  5. Content type: Research article

    Zanthoxylum armatum DC has been an important traditional plant known for its medicinal properties. It is well known for its antimicrobial, larvicidal and cytotoxic activities.

    Authors: Fiaz Alam, Qazi Najum us Saqib and Abdul Waheed

    Citation: BMC Complementary and Alternative Medicine 2017 17:368

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  6. Content type: Research article

    Several lines of evidence suggest the consume of natural products for cancer prevention or treatment. In particular, isothiocyanates (ITCs) exerting anti-cancer properties, have received great interest as pote...

    Authors: Sabrina Giacoppo, Renato Iori, Patrick Rollin, Placido Bramanti and Emanuela Mazzon

    Citation: BMC Complementary and Alternative Medicine 2017 17:362

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  7. Content type: Research article

    Retinal ischemia-related eye diseases result in visual dysfunction. This study investigates the protective effects and mechanisms of Xue-Fu-Zhu-Yu decoction (XFZYD) with respect to retinal ischemia.

    Authors: Shu-Qiu Tan, Xue Geng, Jorn-Hon Liu, Wynn Hwai-Tzong Pan, Li-Xiang Wang, Hui-Kang Liu, Lei Hu and Hsiao-Ming Chao

    Citation: BMC Complementary and Alternative Medicine 2017 17:365

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  8. Content type: Research article

    Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by continuous hyperglycemia associated with insulin resistance and /or reduced insulin secretion. There is an emerging trend regarding the ...

    Authors: Mizher Hezam AL-Zuaidy, Muhammad Waseem Mumtaz, Azizah Abdul Hamid, Amin Ismail, Suhaila Mohamed and Ahmad Faizal Abdul Razis

    Citation: BMC Complementary and Alternative Medicine 2017 17:359

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  9. Content type: Research article

    Sarcopoterium spinosum (S. spinosum) is used by Bedouin medicinal practitioners for the treatment of diabetes. While the anti-diabetic activity of S. spinosum root extract was validate...

    Authors: Uriel Elyasiyan, Adi Nudel, Nir Skalka, Konstantin Rozenberg, Elyashiv Drori, Rachela Oppenheimer, Zohar Kerem and Tovit Rosenzweig

    Citation: BMC Complementary and Alternative Medicine 2017 17:356

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  10. Content type: Research article

    Type 2 diabetes mellitus (T2DM) is a major risk factor for cardiovascular disease, and the prevalence has increased significantly in recent decades to epidemic proportions in China. Individually, fenugreek (Trigo...

    Authors: Juntao Kan, Rodney A. Velliquette, Kerry Grann, Charlie R. Burns, Jeff Scholten, Feng Tian, Qi Zhang and Min Gui

    Citation: BMC Complementary and Alternative Medicine 2017 17:352

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  11. Content type: Research article

    Tagetes minuta has a long record of human use for the treatment of stomach and intestinal diseases. Most drugs used for diseases treatment are less efficacious with side effects and th...

    Authors: Aboi Igwaran, Benson Chucks Iweriebor, Sunday Ofuzim Okoh, Uchechukwu Uchechukwu Nwodo, Larry Chikwelu Obi and Anthony Ifeanyi Okoh

    Citation: BMC Complementary and Alternative Medicine 2017 17:351

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  12. Content type: Research article

    Colitis is a well-known subtype of inflammatory bowel disease and is caused by diverse factors. Previous research has shown that KIOM-MA elicits anti-inflammatory and anti-allergic effects on various diseases....

    Authors: Dong-Gun Kim, Mi-Ra Lee, Jae-Myung Yoo, Kwang-Il Park and Jin-Yeul Ma

    Citation: BMC Complementary and Alternative Medicine 2017 17:354

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  13. Content type: Research article

    Bone defects caused by trauma, infection or tumor resection are common in orthopedic clinic and depending on the extent of the fracture; the vast majority require treatment with bone substitutes. Among the bon...

    Authors: Vicente F. Pinheiro Neto, Rachel M. Ribeiro, Camila S. Morais, Matheus B. Campos, Denilson A. Vieira, Porfírio C. Guerra, Ana L. Abreu-Silva, José R. Silva Junior, Flavia Raquel F. Nascimento, Marilene O. R. Borges and Antonio C.R. Borges

    Citation: BMC Complementary and Alternative Medicine 2017 17:350

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  14. Content type: Research article

    A. cordifolia is a plant widely used in Africa to solve many health problems. In Cameroon, it is used in the treatment of urogenital infections. As a continuation of our search for pha...

    Authors: Merline Namekong Djimeli, Siméon Pierre Chegaing Fodouop, Guy Sedar Singor Njateng, Charles Fokunang, Donald Sedric Tala, Fabrice Kengni and Donatien Gatsing

    Citation: BMC Complementary and Alternative Medicine 2017 17:349

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  15. Content type: Research article

    Axon growth inhibitory factors NogoA/Nogo receptor (NgR) and its signaling pathways RhoA/Rho kinase (ROCK) play a critical role in the repair of nerve damage in multiple sclerosis (MS). Bu Shen Yi Sui Capsule ...

    Authors: Ling Fang, Yongqiang Wang, Qi Zheng, Tao Yang, Peiyuan Zhao, Hui Zhao, Qiuxia Zhang, Yuanyuan Zhao, Fang Qi, Kangning Li, Zhenzhen Chen, Junling Li, Nan Zhang, Yongping Fan and Lei Wang

    Citation: BMC Complementary and Alternative Medicine 2017 17:346

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  16. Content type: Research article

    Xeniji, produced by fermenting various types of foods with lactic acid bacteria and yeast, has been commonly consumed as functional food. However, nutrition value, bioactivities and safety of different ferment...

    Authors: Noraisyah Zulkawi, Kam Heng Ng, Rizi Zamberi, Swee Keong Yeap, Dilan Satharasinghe, Indu Bala Jaganath, Anisah Binti Jamaluddin, Sheau Wei Tan, Wan Yong Ho, Noorjahan Banu Alitheen and Kamariah Long

    Citation: BMC Complementary and Alternative Medicine 2017 17:344

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  17. Content type: Research article

    Rhazya stricta Decne. is a medicinal plant that is widespread in Saudi Arabia and desert areas of the Arabian Peninsula. Its extract contains alkaloids, tannins, and flavonoids that ar...

    Authors: Faisal S. Alagrafi, Abdullah O. Alawad, Nael M. Abutaha, Fahd A. Nasr, Othman A. Alhazzaa, Sultan N. Alharbi, Mohammad N. Alkhrayef, Mohamed Hammad, Ziyad A. Alhamdan, Abdullah D. Alenazi and Mohammad A. Wadaan

    Citation: BMC Complementary and Alternative Medicine 2017 17:342

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  18. Content type: Research article

    The Thai traditional herbal formula–Mathurameha, consisting of 26 medicinal plants, has been used as an alternative and complementary medicine for diabetes treatment in Wangnamyen Hospital, Thailand. To provid...

    Authors: Kullacha Chayarop, Penchom Peungvicha, Rungravi Temsiririrkkul, Yuvadee Wongkrajang, Wongsatit Chuakul and Piyanuch Rojsanga

    Citation: BMC Complementary and Alternative Medicine 2017 17:343

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  19. Content type: Research article

    Black ginseng (Panax ginseng C. A. Meyer), three to nine times-steamed and dried ginseng, has biological and pharmacological activities. In this study, the anti-diabetic effects of the black ginseng ethanol extra...

    Authors: Ok-Hwa Kang, Mi-Yae Shon, Ryong Kong, Yun-Soo Seo, Tian Zhou, Do-Yeon Kim, Yeong-Soo Kim and Dong-Yeul Kwon

    Citation: BMC Complementary and Alternative Medicine 2017 17:341

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