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BMC Complementary and Alternative Medicine

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Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    A variety of anticancer chemotherapeutics induce adverse side effects including myelotoxicity. Dried roots of Phragmites communis Trinius, Phragmitis rhizoma, have been clinically used in traditional folk medicin...

    Authors: Jinhee Kim, You Jin Lee, Young Ah Kim, Eun-Sang Cho, Eunna Huh, Ok-Sun Bang and No Soo Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:393

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  2. Content type: Research article

    [6]-Gingerol, a major component of Zingiber officinale, was previously reported to ameliorate hyperglycemia in type 2 diabetic mice. Endocrine signaling is involved in insulin secretion and is perturbed in db/db ...

    Authors: Mehdi Bin Samad, Md. Nurul Absar Bin Mohsin, Bodiul Alam Razu, Mohammad Tashnim Hossain, Sinayat Mahzabeen, Naziat Unnoor, Ishrat Aklima Muna, Farjana Akhter, Ashraf Ul Kabir and J. M. A. Hannan

    Citation: BMC Complementary and Alternative Medicine 2017 17:395

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  3. Content type: Research article

    It has been reported that royal jelly would reduce melanin synthesis and inhibit the expression of melanogensis related proteins and genes. In this study, we evaluate the anti-melanogenic and depigmenting acti...

    Authors: Chi-Chung Peng, Hui-Tzu Sun, I-Ping Lin, Ping-Chung Kuo and Jen-Chieh Li

    Citation: BMC Complementary and Alternative Medicine 2017 17:392

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  4. Content type: Research article

    The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereot...

    Authors: Patrick Amoateng, Samuel Adjei, Dorcas Osei-safo, Kennedy K. E. Kukuia, Emelia Oppong Bekoe, Thomas K. Karikari and Samuel B. Kombian

    Citation: BMC Complementary and Alternative Medicine 2017 17:389

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  5. Content type: Research article

    Plants are an efficient source of natural antioxidant against free radicals causing kidney damages. Sida cordata ethyl acetate fraction has been reported for strong in vitro antioxidant potency, previously. In th...

    Authors: Naseer Ali Shah, Muhammad Rashid Khan and Dereje Nigussie

    Citation: BMC Complementary and Alternative Medicine 2017 17:388

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  6. Content type: Research article

    Herbology is the prevailing system among the nationally-accepted alternative or complementary systems of medicine. The system is due to its general and patient-oriented methodology, is widely used in the gener...

    Authors: Saiqa Ishtiaq, Maida Akram, Sairah Hafeez Kamran, Uzma Hanif, Muhammad Shaharyar Khan Afridi, Sajid-ur-Rehman, Atika Afzal, Ayesha Asif, Muhammad Younus and Shehla Akbar

    Citation: BMC Complementary and Alternative Medicine 2017 17:387

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  7. Content type: Research article

    Benign prostatic hyperplasia (BPH) is non-cancerous condition of enlargement of the prostate, a common occurrence in older men. The immature fruits of Poncirus trifoliata (L.) Rafinesque (Rutaceae), Ponciri Fruct...

    Authors: Woo-Young Jeon, Ohn Soon Kim, Chang-Seob Seo, Seong Eun Jin, Jung-Ae Kim, Hyeun-Kyoo Shin, Yong-ung Kim and Mee-Young Lee

    Citation: BMC Complementary and Alternative Medicine 2017 17:384

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  8. Content type: Research article

    As per the recent statistical reports of World Health Organisation (WHO), 13% of total global population is obese. Orlistat remains to be the only drug approved for the long term treatment of obesity. Recent f...

    Authors: M. Katoch, A. Paul, G. Singh and S. N. C. Sridhar

    Citation: BMC Complementary and Alternative Medicine 2017 17:385

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  9. Content type: Research article

    Plants have served either as a natural templates for the development of new chemicals or a phytomedicine since antiquity. Therefore, the present study was aimed to appraise the polarity directed antioxidant, c...

    Authors: Madiha Ahmed, Humaira Fatima, Muhammad Qasim, Bilquees Gul and Ihsan-ul-Haq

    Citation: BMC Complementary and Alternative Medicine 2017 17:386

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  10. Content type: Research article

    Epidemiological and experimental evidences have shown cancer as a leading cause of death worldwide. Although the folklore use of plants as a reliable source of health-restoring principles is well-documented, t...

    Authors: Jeremiah Olorunjuwon Olugbami, Robert Damoiseaux, Bryan France, Esther Modupe Onibiyo, Michael Adedapo Gbadegesin, Shivani Sharma, James Kazimierz Gimzewski and Oyeronke Adunni Odunola

    Citation: BMC Complementary and Alternative Medicine 2017 17:381

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  11. Content type: Research article

    Ficus umbellata is a medicinal plant previously shown to endow estrogenic properties. Its major component was isolated and characterized as 7-methoxycoumarin (MC). Noteworthy, coumarin...

    Authors: Stéphane Zingue, Thomas Michel, Chantal Beatrice Magne Nde, Amstrong Nang Njuh, Julia Cisilotto, Derek Tantoh Ndinteh, Colin Clyne, Xavier Fernandez, Tânia Beatriz Creczynski-Pasa and Dieudonné Njamen

    Citation: BMC Complementary and Alternative Medicine 2017 17:383

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  12. Content type: Research article

    The ethnic population of Arunachal Pradesh uses a number of orchids as such, or in decoction for various ailments. Three untapped orchids namely, Rhynchostylis retusa, Tropidia curculioides and Satyrium nepalense...

    Authors: Manisha Bhatnagar, Nandan Sarkar, Nigam Gandharv, Ona Apang, Sarman Singh and Sabari Ghosal

    Citation: BMC Complementary and Alternative Medicine 2017 17:379

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  13. Content type: Research article

    Asthma is characterized by chronic airway inflammation, leading to structura1 changes in the airway, collectively termed airway remodeling. Airway remodeling is thought to contribute to airway hyper responsive...

    Authors: Xiufeng Tang, Honglei Nian, Xiaoxi Li, Yan Yang, Xiujuan Wang, Liping Xu, Haotian Shi, Xinwei Yang and Renhui Liu

    Citation: BMC Complementary and Alternative Medicine 2017 17:380

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  14. Content type: Research article

    Cancer cachexia is associated with increased pro-inflammatory cytokine levels. Centella asiatica (C. asiatica) possesses antioxidant, anti-inflammatory and anti-tumour potential. We investigated the modulation of...

    Authors: Dhaneshree Bestinee Naidoo, Anil Amichund Chuturgoon, Alisa Phulukdaree, Kanive Parashiva Guruprasad, Kapaettu Satyamoorthy and Vikash Sewram

    Citation: BMC Complementary and Alternative Medicine 2017 17:377

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  15. Content type: Research article

    Prostate cancer is the most common cancer in men in the United States. Fucoidan is a bioactive polysaccharide extracted mainly from algae. The aim of this study was to investigate anti-tumor and anti-angiogeni...

    Authors: Xin Rui, Hua-Feng Pan, Si-Liang Shao and Xiao-Ming Xu

    Citation: BMC Complementary and Alternative Medicine 2017 17:378

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  16. Content type: Research article

    In northeastern Brazil, grape pomace has become a potential alternative byproduct because of the recover phenolic compounds from the vinification process. Comparative analyses were performed between lyophilize...

    Authors: José George F. Albuquerque, Valéria L. Assis, Arthur J. P. O. Almeida, Ionaldo J. L. D. Basílio, Melissa N. Luciano, Bruno R. L. A. Meireles, Ângela M. T. M. Cordeiro, Islânia G. A. Araújo, Robson C. Veras, Thaís P. Ribeiro and Isac A. Medeiros

    Citation: BMC Complementary and Alternative Medicine 2017 17:376

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  17. Content type: Research article

    SC-E1 is a novel herbal formula consisting of five oriental medicinal herbs used frequently in traditional herbal medicine for the treatment of inflammatory diseases in Korea. This study examined the effects o...

    Authors: Ju-Yeon Park, Young-Won Kwon, Soo Chil Lee, Sun-Dong Park and Ju-Hee Lee

    Citation: BMC Complementary and Alternative Medicine 2017 17:374

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  18. Content type: Research article

    Chebulic acid (CA) isolated from T. chebula, which has been reported for treating asthma, as a potent anti-oxidant resources. Exposure to ambient urban particulate matter (UPM) considered as a risk for cardiopulm...

    Authors: Kyung-Won Lee, Mi-Hyun Nam, Hee-Ra Lee, Chung-Oui Hong and Kwang-Won Lee

    Citation: BMC Complementary and Alternative Medicine 2017 17:373

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  19. Content type: Research article

    The roots and stem bark of Berberis orthobotrys (Berberidaceae) have long been used traditionally to treat joint pain. Though, it has not been pharmacologically assessed for rheumatoid arthritis. The current stud...

    Authors: Alamgeer, Ambreen Malik Uttra and Umme Habiba Hasan

    Citation: BMC Complementary and Alternative Medicine 2017 17:371

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  20. Content type: Research article

    The emergence of drug resistant malaria is threatening our ability to treat and control malaria in the Southeast Asian region. There is an urgent need to develop novel and chemically diverse antimalarial drugs...

    Authors: Muhammad Bilal Sadiq, Pattamon Tharaphan, Kesinee Chotivanich, Joel Tarning and Anil Kumar Anal

    Citation: BMC Complementary and Alternative Medicine 2017 17:372

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