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BMC Complementary and Alternative Medicine

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Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    Various studies have suggested the effectiveness of Chinese medicine in the treatment of diabetic peripheral neuropathy (DPN). There are several principles and methods in Chinese medicine for the treatment of ...

    Authors: Sharad Panthi, Xirun Jing, Chenghan Gao and Tianshu Gao

    Citation: BMC Complementary and Alternative Medicine 2017 17:424

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  2. Content type: Research article

    Euphorbia hirta linn., is a species of Euphorbiaceae family. They are known as asthma plant, barokhervi. The plant E. hirta is famous for its medicinal importance among the tribal popu...

    Authors: Riazul Haque Tuhin, Mst. Marium Begum, Md. Sohanur Rahman, Rubaba Karim, Taslima Begum, Siraj Uddin Ahmed, Ronia Mostofa, Amir Hossain, Mohamed Abdel-Daim and Rayhana Begum

    Citation: BMC Complementary and Alternative Medicine 2017 17:423

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  3. Content type: Research article

    Hepatocellular carcinoma (HCC) accounts for major cancer-related deaths despite current advanced therapies. Treatment and prognosis of HCC is better in patients with preserved liver function. Many natural prod...

    Authors: Fazal Khan, Tariq Jamal Khan, Gauthaman Kalamegam, Peter Natesan Pushparaj, Adeel Chaudhary, Adel Abuzenadah, Taha Kumosani, Elie Barbour and Mohammed Al-Qahtani

    Citation: BMC Complementary and Alternative Medicine 2017 17:418

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  4. Content type: Research article

    Acorus gramineus has been reported to exhibit various pharmacological effects including inhibition of cholesterol synthesis, enhancement of lipid metabolism, prevention of dementia and...

    Authors: Joo-Myung Moon, Hae-Mi Sung, Hyun-Jung Jung, Jae-Won Seo and Ji-Hyang Wee

    Citation: BMC Complementary and Alternative Medicine 2017 17:414

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  5. Content type: Research article

    This study evaluated the in vitro activity of essential oil extracted from the leaves of Myracrodruon urundeuva.

    Authors: Ítalo Diego Rebouças de Araújo, Nayara Coriolano de Aquino, Andreza Conceição Véras de Aguiar Guerra, Renato Ferreira de Almeida Júnior, Renata Mendonça Araújo, Raimundo Fernandes de Araújo Júnior, Kléber Juvenal Silva Farias, José Veríssimo Fernandes and Vânia Sousa Andrade

    Citation: BMC Complementary and Alternative Medicine 2017 17:419

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  6. Content type: Research article

    Torch ginger (Etlingera elatior, EE) is a ginger plant that found in Southeast Asia. Previous study showed its flowers and leaves composed of several flavonoids with anti-cancer activity. This study aims to inves...

    Authors: Aungkana Krajarng, Malin Chulasiri and Ramida Watanapokasin

    Citation: BMC Complementary and Alternative Medicine 2017 17:415

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  7. Content type: Research article

    Kangfuxin (KFX) is the ethanol extract of Periplaneta americana L, which has been widely used in the Traditional Chinese Medicine for the repair and regeneration of injured organ and tissues with long history. Th...

    Authors: Yan-Fen Huang, Long-Jian Li, Si-Qian Gao, Yang Chu, Jie Niu, Fu-Neng Geng, Yong-Mei Shen and Li-Hua Peng

    Citation: BMC Complementary and Alternative Medicine 2017 17:413

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  8. Content type: Research article

    Curcumin (diferuloylmethane), a polyphenol extracted from the plant Curcuma longa, is widely used in Southeast Asia, China and India in food preparation and for medicinal purposes. Meanwhile, the neuroprotective ...

    Authors: Xin-Shi Wang, Zeng-Rui Zhang, Man-Man Zhang, Miao-Xuan Sun, Wen-Wen Wang and Cheng-Long Xie

    Citation: BMC Complementary and Alternative Medicine 2017 17:412

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  9. Content type: Research article

    The increase in demand and consumption of single clove garlic or ‘Solo garlic’ (Allium sativum) has resulted in an increase in research on its therapeutic properties. The present study aims to evaluate the antiox...

    Authors: Khalid Mohammed Naji, Elham Shukri Al-Shaibani, Fatima A. Alhadi, Safa’a Abdulrzaq Al-Soudi and Myrene R. D’souza

    Citation: BMC Complementary and Alternative Medicine 2017 17:411

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  10. Content type: Research article

    Electroacupuncture (EA) has been applied to treat and prevent diseases for years. However, molecular events happened in both the acupunctured site and the internal organs after EA stimulation have not been cla...

    Authors: Jing-Shan Wu, Hsin-Yi Lo, Chia-Cheng Li, Feng-Yuan Chen, Chien-Yun Hsiang and Tin-Yun Ho

    Citation: BMC Complementary and Alternative Medicine 2017 17:406

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  11. Content type: Research article

    Trema orientalis (T. orientalis Linn) has been used in the management of malaria in the western part of Nigeria and despite its application in ethnomedicine, there is dearth of scienti...

    Authors: John Oludele Olanlokun, Oluwole Moses David and Anthony Jide Afolayan

    Citation: BMC Complementary and Alternative Medicine 2017 17:407

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  12. Content type: Research article

    Onchocerciasis is one of the tropical neglected diseases (NTDs) caused by the nematode Onchocerca volvulus. Control strategies currently in use rely on mass administration of ivermectin, which has marked activity...

    Authors: Justin Kalmobé, Dieudonné Ndjonka, Djafsia Boursou, Jacqueline Dikti Vildina and Eva Liebau

    Citation: BMC Complementary and Alternative Medicine 2017 17:404

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  13. Content type: Research article

    Hyperlipidaemia is the major risk factor contributing to the development and progression of atherosclerosis, fatty liver and cerebrovascular disease. Pleurotus eryngii (P. eryngii) is rich in biologically active ...

    Authors: Chen Zhang, Juan Li, Jing Wang, Xingling Song, Jianjun Zhang, Shang Wu, Chunlong Hu, Zhiyuan Gong and Le Jia

    Citation: BMC Complementary and Alternative Medicine 2017 17:403

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  14. Content type: Research article

    Holarrhena antidysenterica has been employed as an ethnobotanical plant for the treatment of dysentery, diarrhoea, fever, and bacterial infections. Biological activities of the princip...

    Authors: Thanyaluck Siriyong, Potjanee Srimanote, Sasitorn Chusri, Boon-ek Yingyongnarongkul, Channarong Suaisom, Varomyalin Tipmanee and Supayang Piyawan Voravuthikunchai

    Citation: BMC Complementary and Alternative Medicine 2017 17:405

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  15. Content type: Research article

    Studies of the effects of electromagnetic fields (EMFs) on cartilaginous cells show a broad range of outcomes. However EMFs are not yet clinically applied as standard treatment of osteoarthritis, as EMF effect...

    Authors: Julia Isabelle Redeker, Bärbel Schmitt, Nele Pascale Grigull, Christian Braun, Andreas Büttner, Volkmar Jansson and Susanne Mayer-Wagner

    Citation: BMC Complementary and Alternative Medicine 2017 17:402

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  16. Content type: Research article

    Our previous study demonstrated that an up-regulation of the Brain-Derived Neurotrophic Factor (BDNF) signaling pathway is involved the mechanism causing the recurrence of triple negative breast cancer. The ai...

    Authors: Jen-Hwey Chiu, Fang-Pey Chen, Yi-Fang Tsai, Man-Ting Lin, Ling-Ming Tseng and Yi-Ming Shyr

    Citation: BMC Complementary and Alternative Medicine 2017 17:401

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  17. Content type: Research article

    The resistance of some medico-veterinary parasite strains as well as the unavailability and toxicity of synthetic anthelminthics on humans, animals and the impacts of their residues in the environment have pus...

    Authors: Sergine Errole Ngouateu Teufack, Gertrude NMbogning Tayo, Marc Ngangout Alidou, Jeannette Yondo, Amely Frankline Djiomene, Josué Wabo Poné and Faùily Mpoame Mbida

    Citation: BMC Complementary and Alternative Medicine 2017 17:400

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  18. Content type: Research article

    Chronic stress contributes to the development of brain disorders, such as neurodegenerative and psychiatric diseases. Oxidative damage is well known as a causative factor for pathogenic process in brain tissue...

    Authors: Hyun-Yong Lee, Jin-Seok Lee, Hyeong-Geug Kim, Won-Yong Kim, Seung-Bae Lee, Yung-Hyun Choi and Chang-Gue Son

    Citation: BMC Complementary and Alternative Medicine 2017 17:397

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  19. Content type: Research article

    Arachidonic acid metabolism by cyclooxygenase (COX) is a major pathway for blood platelets’ activation, which is associated with pro-thrombotic platelet activity and the production of pro-inflammatory mediator...

    Authors: Michal Bijak and Joanna Saluk-Bijak

    Citation: BMC Complementary and Alternative Medicine 2017 17:396

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  20. Content type: Research article

    The common usage of chewing sticks prepared from Neem tree (Azadirachta indica) in India suggests its potential efficacy in periodontal diseases. The objective of this study is to explore the antibacterial effect...

    Authors: Leali Heyman, Yael Houri-Haddad, Samuel N. Heyman, Isaac Ginsburg, Yossi Gleitman and Osnat Feuerstein

    Citation: BMC Complementary and Alternative Medicine 2017 17:399

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