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BMC Complementary and Alternative Medicine

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Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    Alkaloids have been considered as the most promising bioactive ingredients in plant species from the genus Zanthoxylum. This study reports on the compositions and contents of the Zanthoxylum alkaloids (ZAs) from ...

    Authors: Yongqiang Tian, Chunyun Zhang and Mingquan Guo

    Citation: BMC Complementary and Alternative Medicine 2017 17:460

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  2. Content type: Research article

    Tinospora cordifolia (Guduchi or Amrita) is an important drug of Ayurvedic System of Medicine and found mention in various classical texts for the treatment of diseases such as jaundic...

    Authors: Picheswara Rao Polu, Udupa Nayanbhirama, Saleemulla Khan and Rajlexmi Maheswari

    Citation: BMC Complementary and Alternative Medicine 2017 17:457

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  3. Content type: Research article

    So-ochim-tang-gamibang (SOCG) is a decoction formula which has been used to improve mental activity in traditional Korean medicine. The present study was performed to evaluate whether ...

    Authors: Hwa Chul Shin, Jae Ho Lee, Ki Joong Kim, Hyun Jin Shin, Jeong June Choi, Chan Yong Lee, Uk Namgung and In Chul Jung

    Citation: BMC Complementary and Alternative Medicine 2017 17:456

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  4. Content type: Research article

    Nonalcoholic steatohepatitis (NASH) is a progressive form of nonalcoholic fatty liver disease, for which there is currently no safe and effective drug for therapy. In this study, we explored the effects of tau...

    Authors: Wenhua Zhu, Siwen Chen, Ronggui Chen, Zhiqing Peng, Jun Wan and Benyan Wu

    Citation: BMC Complementary and Alternative Medicine 2017 17:455

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  5. Content type: Research article

    Radix puerariae (RP) is a herbal medicines for diabetes, mainly because of anti-oxidative, insulin resistance and hypoglycemic effect. Fructus crataegi (FC) also possesses strong antioxidant activity in vitro....

    Authors: Zhengyue Chen, Yanyan Yuan, Xinrong Zou, Mengqi Hong, Ming Zhao, Yu Zhao, Yuanping Liu, Guofu Li, Yabin Zhu, Lin Luo, Beiyan Bao and Shizhong Bu

    Citation: BMC Complementary and Alternative Medicine 2017 17:454

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  6. Content type: Research article

    Foodstuffs of both plant and animal origin contain a wide range of bioactive compounds. Although human intervention studies are mandatory to assess the health effects of bioactives, the in vitro approach is of...

    Authors: Mattia Di Nunzio, Veronica Valli, Lidia Tomás-Cobos, Teresa Tomás-Chisbert, Lucía Murgui-Bosch, Francesca Danesi and Alessandra Bordoni

    Citation: BMC Complementary and Alternative Medicine 2017 17:453

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  7. Content type: Research article

    Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders that are mediated by pathogenic Th1 and Th17 cells. Previous studies have demonstrated that taheebo water extract (TWE) derived from Tabebuia ...

    Authors: Hyun Jung Park, Sung Won Lee, Dong-Joo Kwon, Seong-Il Heo, Se-Ho Park, Sun Young Kim and Seokmann Hong

    Citation: BMC Complementary and Alternative Medicine 2017 17:448

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  8. Content type: Research article

    Previous studies have revealed that gypenosides (GPS) improve the symptoms of anxiety disorders in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned rat model of Parkinson’s disease (PD). The pres...

    Authors: Ting Ting Zhao, Kyung Sook Kim, Keon Sung Shin, Hyun Jin Park, Hyun Jeong Kim, Kyung Eun Lee and Myung Koo Lee

    Citation: BMC Complementary and Alternative Medicine 2017 17:449

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  9. Content type: Research article

    Mutations play a major role in the pathogenesis and development of several chronic degenerative diseases including cancer. It follows, therefore that antimutagenic compound may inhibit the pathological process...

    Authors: Tshepiso Jan Makhafola, Esameldin Elzein Elgorashi, Lyndy Joy McGaw, Maurice Ducret Awouafack, Luc Verschaeve and Jacobus Nicolaas Eloff

    Citation: BMC Complementary and Alternative Medicine 2017 17:446

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  10. Content type: Research article

    “Jiedu Huayu” (JDHY) granules are traditional Chinese herbal compounds that have been used to treat severe liver injury for many years. The purpose of the current study is to evaluate the safety of JDHY granules.

    Authors: Minggang Wang, Hua Qiu, Rongzhen Zhang, Fuli Long and Dewen Mao

    Citation: BMC Complementary and Alternative Medicine 2017 17:450

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  11. Content type: Research article

    The concept of botanical therapeutics has revitalized due to wide importance of plant derived pharmaceuticals. Therefore, the ameliorative characteristics of Ajuga bracteosa were studied.

    Authors: Syeda Saniya Zahra, Madiha Ahmed, Muhammad Qasim, Bilquees Gul, Muhammad Zia, Bushra Mirza and Ihsan-ul Haq

    Citation: BMC Complementary and Alternative Medicine 2017 17:443

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  12. Content type: Research article

    Although it has been reported to contain high polyphenols, the pharmacological studies of the calyx of Diospyros kaki Thunb (DKC) have not been elucidated in detail. In this study, we elucidated anti-cancer activ...

    Authors: Su Bin Park, Gwang Hun Park, Hun Min Song, Ho-Jun Son, Yurry Um, Hyun-Seok Kim and Jin Boo Jeong

    Citation: BMC Complementary and Alternative Medicine 2017 17:445

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  13. Content type: Research article

    Agrimonia pilosa Ledeb. is a medicinal plant with physiological activities such as anti-cancer, antioxidant, anti-inflammatory activities and in vitro anti-diabetic activity. However, ...

    Authors: Hwan Hee Jang, Song Yee Nam, Mi Ju Kim, Jung Bong Kim, Jeong Sook Choi, Haeng Ran Kim and Young Min Lee

    Citation: BMC Complementary and Alternative Medicine 2017 17:442

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  14. Content type: Research article

    A variety of plants in Acanthaceae have long been used in traditional Thai ailment and commercialised with significant economic value. Nowadays medicinal plants are sold in processed forms and thus morphologic...

    Authors: Tanakorn Suesatpanit, Kitisak Osathanunkul, Panagiotis Madesis and Maslin Osathanunkul

    Citation: BMC Complementary and Alternative Medicine 2017 17:437

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  15. Content type: Research article

    Tetracera indica Merr. (Family: Dilleniaceae), known to the Malay as ‘Mempelas paya’, is one of the medicinal plants used in the treatment of diabetes in Malaysia. However, no proper s...

    Authors: Md. Mahmudul Hasan, Qamar Uddin Ahmed, Siti Zaiton Mat Soad, Jalifah Latip, Muhammad Taher, Tengku Muhamad Faris Syafiq, Murni Nazira Sarian, Alhassan Muhammad Alhassan and Zainul Amiruddin Zakaria

    Citation: BMC Complementary and Alternative Medicine 2017 17:431

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  16. Content type: Research article

    Recent reports have demonstrated that impaired barrier function and local microinflammation in the duodenal mucosa contribute to the pathogeneses of functional dyspepsia (FD). Thus, restoring normal barrier in...

    Authors: Xiongfei Chang, Luqing Zhao, Jiajia Wang, Xiaofang Lu and Shengsheng Zhang

    Citation: BMC Complementary and Alternative Medicine 2017 17:432

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  17. Content type: Research article

    P-113 (AKRHHGYKRKFH-NH2) is a 12-amino-acid histidine-rich peptide derived from histatin 5 that is highly degradable in high salt concentrations and biological fluids such as serum, plasma and saliva. Nal-P-11...

    Authors: Hong-yan Wang, Li Lin, Wei Fu, Hui-Yuan Yu, Ning Yu, Li-si Tan, Jya-wei Cheng and Ya-ping Pan

    Citation: BMC Complementary and Alternative Medicine 2017 17:426

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  18. Content type: Research article

    GS-E3D is a newly developed pectin lyase-modified red ginseng extract. The purpose of this study was to investigate the therapeutic effects of GS-E3D on diabetes-related renal dysfunction in streptozotocin-ind...

    Authors: Chan-Sik Kim, Kyuhyung Jo, Jin Sook Kim, Mi-Kyung Pyo and Junghyun Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:430

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  19. Content type: Research article

    In immunocompromised patients, human cytomegalovirus (HCMV) infection can lead to severe, life-threatening diseases, such as pneumonitis, hepatitis, gastrointestinal tract disease, and retinitis. We previously...

    Authors: Sohee Bae, Se Chan Kang and Yoon-Jae Song

    Citation: BMC Complementary and Alternative Medicine 2017 17:428

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