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BMC Complementary and Alternative Medicine

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Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    We previously reported that a methanol extract of Glycyrrhizae radix (MEGR) blocked methamphetamine-induced locomotor sensitization and conditioned place preference in rats. In the present study, the effects of M...

    Authors: Zheng Lin Zhao, Sang Chan Kim, Hong Feng Liu, Yi Yan Wu, Li Bo Li, Yu Hua Wang, Yu Jiao, Yu Fan, Chul Won Lee, Bong Hyeo Lee, Il Je Cho, Chae Ha Yang and Rong Jie Zhao

    Citation: BMC Complementary and Alternative Medicine 2017 17:493

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  2. Content type: Research article

    Research of natural products from traditionally used medicinal plants to fight against the human ailments is fetching attention of researchers worldwide. Bidens pilosa Linn. var. Radiata (Asteraceae) is well know...

    Authors: Garima Singh, Ajit Kumar Passsari, Pratibha Singh, Vincent Vineeth Leo, Sarathbabu Subbarayan, Brijesh Kumar, Bhim Pratap Singh, Hauzel lalhlenmawia and Nachimuthu Senthil Kumar

    Citation: BMC Complementary and Alternative Medicine 2017 17:492

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  3. Content type: Research article

    Melastoma malabathricum L. (family Melastomaceae; MM) and Muntingia calabura L. (family Elaeocarpaceae; MC) have been separately reported to possess gastroprotective activity. In an at...

    Authors: Siti Zawanah Halim, Zainul Amiruddin Zakaria, Maizatul Hasyima Omar, Norhafizah Mohtarrudin, Ikarastika Rahayu Abdul Wahab and Muhammad Nazrul Hakim Abdullah

    Citation: BMC Complementary and Alternative Medicine 2017 17:488

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  4. Content type: Research article

    Coix lacryma-jobi var. ma-yuen (Rom.Caill.) Stapf has been used in China as an herbal medicine. Many studies of this plant have reported anti-proliferative and apoptotic activities on ...

    Authors: Eun Suk Son, Young Ock Kim, Chun Geon Park, Kyung Hun Park, Sung Hwan Jeong, Jeong-Woong Park and Se-Hee Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:486

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  5. Content type: Research article

    During ischemic stroke (IS), adenosine 5′-triphosphate (ATP) is released from damaged nerve cells of the infract core region to the extracellular space, invoking peri-infarct glial cellular P2 purinoceptors si...

    Authors: Jia Huang, Xiaofang You, Weilin Liu, Changming Song, Xiaomin Lin, Xiufeng Zhang, Jing Tao and Lidian Chen

    Citation: BMC Complementary and Alternative Medicine 2017 17:480

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  6. Content type: Research article

    Essential hypertension is mainly caused by endothelial dysfunction which results from nitric oxide (NO) deficiency. The present study was design to evaluate the protective effect of Bidens pilosa ethylene acetate...

    Authors: Danielle Claude Bilanda, Paul Désiré D. Dzeufiet, Léontine Kouakep, Bibi Farouck O. Aboubakar, Léonard Tedong, Pierre Kamtchouing and Théophile Dimo

    Citation: BMC Complementary and Alternative Medicine 2017 17:479

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  7. Content type: Research article

    Oxidative stress has a pivotal role in the pathogenesis and development of diabetic peripheral neuropathy (DPN), the most common and debilitating complications of diabetes mellitus. There is accumulating evide...

    Authors: Davood Nasiry, Ali Reza khalatbary, Hassan Ahmadvand, Fereshteh Talebpour Amiri and Esmaeil Akbari

    Citation: BMC Complementary and Alternative Medicine 2017 17:476

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  8. Content type: Research article

    Hypertension is one of the most important risk factors for cardiovascular disease (CVD) and a worldwide problem. Despite increases in the development of synthetic drugs for hypertension treatment, the rate of ...

    Authors: Bumjung Kim, Youngki Kwon, Somin Lee, Kyungjin Lee, Inhye Ham and Ho-Young Choi

    Citation: BMC Complementary and Alternative Medicine 2017 17:474

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  9. Content type: Research article

    Many people still experience pain and inflammation regardless of the available drugs for treatments. In addition, the available drugs have many side effects, which necessitated a quest for new drugs from sever...

    Authors: Yohannes Tamrat, Teshome Nedi, Solomon Assefa, Tilahun Teklehaymanot and Workineh Shibeshi

    Citation: BMC Complementary and Alternative Medicine 2017 17:473

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  10. Content type: Research article

    Cisplatin is widely used chemotherapeutic agent for cancer treatment with limited uses due to its neurotoxic side effect. The aim of this study was to determine the potential preventive effects of rutin on the...

    Authors: Mashal M. Almutairi, Wael A. Alanazi, Musaad A. Alshammari, Moureq Rashed Alotaibi, Ali R. Alhoshani, Salim Salah Al-Rejaie, Mohamed M. Hafez and Othman A. Al-Shabanah

    Citation: BMC Complementary and Alternative Medicine 2017 17:472

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  11. Content type: Research article

    Cerebral edema, erupting simultaneously with severe ischemic stroke, might lead to increased intracranial pressure, cerebral herniation, and ultimately death. Studies conducted previously by our team have demo...

    Authors: Nannan Yu, Zhenguo Wang, Yucen Chen, Juntao Yang, Xuan Lu, Yi Guo, Zelin Chen and Zhifang Xu

    Citation: BMC Complementary and Alternative Medicine 2017 17:470

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  12. Content type: Research article

    Propolis and its major constituent – caffeic acid phenethyl ester (CAPE) have good abilities on antitumor and anti-inflammation. However, little is known about the actions of propolis and CAPE on tumor in infl...

    Authors: Huasong Chang, Yuehua Wang, Xusheng Yin, Xinying Liu and Hongzhuan Xuan

    Citation: BMC Complementary and Alternative Medicine 2017 17:471

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  13. Content type: Research article

    Mango mistletoes Dendrophthoe pentandra (MMDP) extract has attracted interest due to its pharmacological properties, including gastro protective effects. The aim of this study was to investigate whether MMDP extr...

    Authors: Agustina Tri Endharti and Sofy Permana

    Citation: BMC Complementary and Alternative Medicine 2017 17:468

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  14. Content type: Research article

    Extracts of plants have been considered as sources of natural antioxidant agents. In this study, we aimed to explore the antioxidant capacity of the aqueous root extract of Asparagus cochinchinensis (Lour.) Merr.

    Authors: Linghua Lei, Yanhua Chen, Lijun Ou, Yinglong Xu and Xiaoying Yu

    Citation: BMC Complementary and Alternative Medicine 2017 17:469

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  15. Content type: Research article

    The emergence of multidrug-resistant bacteria is a worldwide concern and in order to find an alternative to this problem, the occurrence of antimicrobial compounds in Plectranthus amboinicus essential oil was inv...

    Authors: Sara Edwirgens Costa Benício Vasconcelos, Hider Machado Melo, Theodora Thays Arruda Cavalcante, Francisco Eduardo Aragão Catunda Júnior, Mário Geraldo de Carvalho, Francisca Gleire Rodrigues Menezes, Oscarina Viana de Sousa and Renata Albuquerque Costa

    Citation: BMC Complementary and Alternative Medicine 2017 17:462

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  16. Content type: Research article

    Plants produce secondary metabolites that often possess widespread bioactivity, and are then known as phytochemicals. We previously determined that several phytochemical-rich food-derived preparations were act...

    Authors: Sabrina M. Noritake, Jenny Liu, Sierra Kanetake, Carol E. Levin, Christina Tam, Luisa W. Cheng, Kirkwood M. Land and Mendel Friedman

    Citation: BMC Complementary and Alternative Medicine 2017 17:461

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  17. Content type: Research article

    Alkaloids have been considered as the most promising bioactive ingredients in plant species from the genus Zanthoxylum. This study reports on the compositions and contents of the Zanthoxylum alkaloids (ZAs) from ...

    Authors: Yongqiang Tian, Chunyun Zhang and Mingquan Guo

    Citation: BMC Complementary and Alternative Medicine 2017 17:460

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  18. Content type: Research article

    Tinospora cordifolia (Guduchi or Amrita) is an important drug of Ayurvedic System of Medicine and found mention in various classical texts for the treatment of diseases such as jaundic...

    Authors: Picheswara Rao Polu, Udupa Nayanbhirama, Saleemulla Khan and Rajlexmi Maheswari

    Citation: BMC Complementary and Alternative Medicine 2017 17:457

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  19. Content type: Research article

    So-ochim-tang-gamibang (SOCG) is a decoction formula which has been used to improve mental activity in traditional Korean medicine. The present study was performed to evaluate whether ...

    Authors: Hwa Chul Shin, Jae Ho Lee, Ki Joong Kim, Hyun Jin Shin, Jeong June Choi, Chan Yong Lee, Uk Namgung and In Chul Jung

    Citation: BMC Complementary and Alternative Medicine 2017 17:456

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