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BMC Complementary and Alternative Medicine

Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    Parrotiopsis jacquemontiana (Decne) Rehder. is locally used for skin infections and in wound healing. In this study we have evaluated methanol extract of its leaves and derived fractions against the clinical mult...

    Authors: Saima Ali, Muhammad Rashid Khan, Irfanullah, Moniba Sajid and Zartash Zahra

    Citation: BMC Complementary and Alternative Medicine 2018 18:43

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  2. Content type: Research article

    Cold hypersensitivity in the hands and feet (CHHF) is a common symptom in Korea and patients with CHHF complain of coldness in the hands and feet in an environment that is not considered cold by unaffected peo...

    Authors: Kwang-Ho Bae, Ho-Yeon Go, Ki-Hyun Park, Ilkoo Ahn, Youngheum Yoon and Siwoo Lee

    Citation: BMC Complementary and Alternative Medicine 2018 18:40

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  3. Content type: Research article

    Our team has identified 17 Boreal forest species from the traditional pharmacopeia of the Eastern James Bay Cree that presented promising in vitro and in vivo biological activities in the context of type 2 dia...

    Authors: Shilin Li, Sarah Pasquin, Hoda M. Eid, Jean-François Gauchat, Ammar Saleem and Pierre S. Haddad

    Citation: BMC Complementary and Alternative Medicine 2018 18:37

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  4. Content type: Research article

    Despite the remarkable progress in cancer therapy in recent years, this disease still remains a serious public health concern. The use of natural products has been and continues to be one of the most effective...

    Authors: Victor Kuete, Dominique Ngnintedo, Ghislain W. Fotso, Oğuzhan Karaosmanoğlu, Bonaventure T. Ngadjui, Felix Keumedjio, Samuel O. Yeboah, Kerstin Andrae-Marobela and Hülya Sivas

    Citation: BMC Complementary and Alternative Medicine 2018 18:36

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  5. Content type: Research article

    It has been observed that the various part of Baccaurea ramiflora plant is used in rheumatoid arthritis, cellulitis, abscesses, constipation and injuries. This plant also has anticholinergic, hypolipidemic, hypog...

    Authors: Mst. Luthfun Nesa, S. M. Sajedul Karim, Khairunasa Api, Md. Moklesur Rahman Sarker, Md. Monirul Islam, Asma Kabir, Mithun Kumar Sarker, Kamrun Nahar, Mohammad Asadujjaman and Mohammad Sirajum Munir

    Citation: BMC Complementary and Alternative Medicine 2018 18:35

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  6. Content type: Research article

    Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound. However, elucidating the related molecular biological mechanism of how...

    Authors: Le Kuai, Jing-ting Zhang, Yu Deng, Shun Xu, Xun-zhe Xu, Min-feng Wu, Dong-jie Guo, Yu Chen, Ren-jie Wu, Xing-qiang Zhao, Hua Nian, Bin Li and Fu-lun Li

    Citation: BMC Complementary and Alternative Medicine 2018 18:32

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  7. Content type: Research article

    Icariin (ICA), a major ingredient of Epimediumbrevicornum, has various pharmacological activities including central nervous system protective functions such as the improvement of learning and memory function in m...

    Authors: Xiaolong Fu, Shujun Li, Shaoyu Zhou, Qin Wu, Feng Jin and Jingshan Shi

    Citation: BMC Complementary and Alternative Medicine 2018 18:34

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  8. Content type: Research article

    Natural products obtained from plants can be potent sources for developing a variety of pharmaceutical products. Allium species have been widely studied for their anti-cancer effects and presented promising resul...

    Authors: Ovgu Isbilen, Nahit Rizaner and Ender Volkan

    Citation: BMC Complementary and Alternative Medicine 2018 18:30

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  9. Content type: Research article

    Oxidative stress as well as bacterial and fungal infections are common source of diseases while plants are source of medication for curative or protective purposes. Hence, aim of study was to compare the pharm...

    Authors: Iram Fatima, Sobia Kanwal and Tariq Mahmood

    Citation: BMC Complementary and Alternative Medicine 2018 18:27

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  10. Content type: Research article

    Cupressus macrocarpa Hartw and Corymbia citriodora (Hook.) K.D. Hill & L.A.S. Johnson, widely grown in many subtropical areas, are used for commercial purposes, such as in perfumery, cosmetics, and room freshener...

    Authors: Mohamed Z. M. Salem, Hosam O. Elansary, Hayssam M. Ali, Ahmed A. El-Settawy, Mohamed S. Elshikh, Eslam M. Abdel-Salam and Krystyna Skalicka-Woźniak

    Citation: BMC Complementary and Alternative Medicine 2018 18:23

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  11. Content type: Research article

    Pelargonium sidoides (PS) and Coptis chinensis root (CR) have traditionally been used to treat various diseases, including respiratory and gastrointestinal infections, dysmenorrhea, and hepatic disorders. The pre...

    Authors: Sang Mi Park, Byung-Gu Min, Ji Yun Jung, Kyung Hwan Jegal, Chul Won Lee, Kwang Youn Kim, Young Woo Kim, Youn-Woong Choi, Il Je Cho, Sae Kwang Ku and Sang Chan Kim

    Citation: BMC Complementary and Alternative Medicine 2018 18:20

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  12. Content type: Research article

    Based on clinical medications and related studies, we established a Yang-Gan Jie-Du Sang-Jie (YGJDSJ) herbal formula for hepatocarcinoma treatment. In present study, we evaluated the anti-cancer potential of Y...

    Authors: Bing Hu, Tong Zhang, Hong-Mei An, Jia-Lu Zheng, Xia Yan and Xiao-Wei Huang

    Citation: BMC Complementary and Alternative Medicine 2018 18:17

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  13. Content type: Research article

    Nutmeg is the seed kernel inside the fruit of Myristica fragrans Houtt. (Myristicaceae). It possesses various pharmacological activities but is used in Cameroon only for its flavor in making cakes. The present st...

    Authors: Joachim K. Dzotam, Ingrid Konga Simo, Gabin Bitchagno, Ilhami Celik, Louis P. Sandjo, Pierre Tane and Victor Kuete

    Citation: BMC Complementary and Alternative Medicine 2018 18:15

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  14. Content type: Research article

    Fructose-mediated protein glycation (fructation) has been linked to an increase in diabetic and cardiovascular complications due to over consumption of high-fructose containing diets in recent times. The objec...

    Authors: Hardik Ghelani, Valentina Razmovski-Naumovski, Rajeswara Rao Pragada and Srinivas Nammi

    Citation: BMC Complementary and Alternative Medicine 2018 18:13

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  15. Content type: Research article

    Inflammation has been implicated in many disorders, including cancer and available therapies elicit adverse effects. Plants of the family Rubiaceae have shown potency against inflammation. The anti-inflammator...

    Authors: Oluwayinka Olufunmilayo Owolabi, Dorcas Bolanle James, Ibrahim Sani, Binda T. Andongma, Opeoluwa O. Fasanya and Barnabas Kure

    Citation: BMC Complementary and Alternative Medicine 2018 18:12

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  16. Content type: Research article

    The highbush blueberry (Vaccinium corymbosum) has a beneficial effect on several aspects of human health. The present study investigated the effects of highbush blueberry proanthocyanidins (PACs) on the virulence...

    Authors: Amel Ben Lagha, Geneviève LeBel and Daniel Grenier

    Citation: BMC Complementary and Alternative Medicine 2018 18:10

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  17. Content type: Research article

    Costus speciosus, Cymbopogon citratus, and Tabernaemontana coronaria are herbal plants traditionally used as remedies for symptoms of tuberculosis (TB) including cough. The aims of the present study were to evalu...

    Authors: Suriyati Mohamad, Nur Najihah Ismail, Thaigarajan Parumasivam, Pazilah Ibrahim, Hasnah Osman and Habibah A. Wahab

    Citation: BMC Complementary and Alternative Medicine 2018 18:5

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  18. Content type: Research article

    An impaired leukocytes function is the factor causing the susceptibility of patients with diabetes mellitus to infections. The outmost importance for the understanding of the immunological processes involved i...

    Authors: Mariia Nagalievska, Mariya Sabadashka, Halyna Hachkova and Nataliia Sybirna

    Citation: BMC Complementary and Alternative Medicine 2018 18:4

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  19. Content type: Research article

    The medicinal importance of a novel plant Olax nana Wall. ex Benth. (family: Olacaceae) was revealed for the first time via HPLC-DAD finger printing, qualitative phytochemical analysis, antioxidant, cholinesteras...

    Authors: Muhammad Ovais, Muhammad Ayaz, Ali Talha Khalil, Sayed Afzal Shah, Muhammad Saeed Jan, Abida Raza, Muhammad Shahid and Zabta Khan Shinwari

    Citation: BMC Complementary and Alternative Medicine 2018 18:1

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  20. Content type: Research article

    Basophilic granulocytes (BGs) not only initiate the induction of Th2 cell differentiation, but also amplify the ongoing Th2 response. Shuang-Huang-Lian (SHL) is clinically used for relieving type I hypersensit...

    Authors: Qiaoling Fei, Yixin Han, Ruijuan Qi, Yuan Gao, Lei Fang, Rui Hou, Runlan Cai and Yun Qi

    Citation: BMC Complementary and Alternative Medicine 2018 18:2

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