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BMC Complementary and Alternative Medicine

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Basic research

Edited by Jacobus Eloff, Victor Kuete and Insop Shim

This section covers pre-clinical, in vitro and in vivo studies related to interventions or resources in the complementary medicine field, including the isolation and purification or herbal remedies, toxicological studies and research into the biological mechanisms of action of the intervention or resource.

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  1. Content type: Research article

    Various plant extracts have been suggested to be used as auxiliary agents in chemotherapy considering their anti-proliferative effect on cancer cells. However, recent reports reveal that plant extracts may fun...

    Authors: Hai Li and Chen Chen

    Citation: BMC Complementary and Alternative Medicine 2017 17:538

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  2. Content type: Research article

    Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic synovitis, cartilage degradation and bone deformities. Synovitis is the term for inflammation of the synovial membrane, an early stage of ...

    Authors: Manatsanan Khansai, Thanyaluck Phitak, Jeerawan Klangjorhor, Sasimol Udomrak, Kanda Fanhchaksai, Peraphan Pothacharoen and Prachya Kongtawelert

    Citation: BMC Complementary and Alternative Medicine 2017 17:532

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  3. Content type: Research article

    Quercetin (QCT) is a flavonol present in many vegetables, it is proved to show chemo preventive effect against lung, cervical, prostate, breast and colon cancer due to its anti-inflammatory, anti-tumor and ant...

    Authors: Haojie Liu and Ming Zhou

    Citation: BMC Complementary and Alternative Medicine 2017 17:531

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  4. Content type: Research article

    Acupuncture has been used as a common therapeutic tool in many disorders including anxiety and depression. Serotonin transporter (SERT) plays an important role in the pathology of anxiety and other mood disord...

    Authors: Tae Young Yang, Eun Young Jang, Yeonhee Ryu, Gyu Won Lee, Eun Byeol Lee, Suchan Chang, Jong Han Lee, Jin Suk Koo, Chae Ha Yang and Hee Young Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:528

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  5. Content type: Research article

    Ethnobatanical survey associates Sapium ellipticum (SE) with antidiabetic usage among other medicinal functions in different parts of Africa. More importantly, previous studies on the plant extract in our laborat...

    Authors: Osasenaga Macdonald Ighodaro and Oluseyi Adeboye Akinloye

    Citation: BMC Complementary and Alternative Medicine 2017 17:525

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  6. Content type: Research article

    N-butylidenephthalide (BP) isolated from Radix Angelica Sinensis (Danggui) exhibits anti-tumorigenic effect in various cancer cells both in vivo and in vitro. The effect of BP in bladder cancer treatment is still...

    Authors: Sheng-Chun Chiu, Tsung-Lang Chiu, Sung-Ying Huang, Shu-Fang Chang, Shee-Ping Chen, Cheng-Yoong Pang and Teng-Fu Hsieh

    Citation: BMC Complementary and Alternative Medicine 2017 17:523

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  7. Content type: Research article

    According to only a handful of historical sources, Osmunda regalis, the royal fern, has been used already in the middle age as an anti-cancer remedy. To examine this ancient cancer cure, an ethanolic extract of t...

    Authors: Marianne Schmidt, Josef Skaf, Georgiana Gavril, Christine Polednik, Jeanette Roller, Michael Kessler and Ulrike Holzgrabe

    Citation: BMC Complementary and Alternative Medicine 2017 17:518

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  8. Content type: Research article

    European mistletoe (Viscum album) products used in cancer therapy are frequently combined with other anti-cancer-drugs. Hence, potential herb-drug interactions have become a major safety concern in mistletoe ther...

    Authors: Michael Schink and Oliver Dehus

    Citation: BMC Complementary and Alternative Medicine 2017 17:521

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  9. Content type: Research article

    Salmonella enterica serovar Typhimurium is a foodborne pathogen that triggers inflammatory responses in the intestines of humans and livestock. Colla corii asini is a traditional medic...

    Authors: Kwang-il Park, Mi-ra Lee, Tae-woo Oh, Kwang-Youn Kim and Jin-yeul Ma

    Citation: BMC Complementary and Alternative Medicine 2017 17:520

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  10. Content type: Research article

    Compound Muniziqi granule (MNZQ) is a multi-component herbal preparation and a popular traditional Uighur medicine used in China for treating endocrine...

    Authors: Nan Zou, Yue Wei, Fenghua Li, Yang Yang, Xuemei Cheng and Changhong Wang

    Citation: BMC Complementary and Alternative Medicine 2017 17:517

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  11. Content type: Research article

    Galetin 3,6-dimethyl ether (FGAL) is a flavonoid isolated from aerial parts of Piptadenia stipulacea. Previously, FGAL was shown to inhibit both carbachol- and oxytocin-induced phasic contractions in the rat uter...

    Authors: Juliana da Nóbrega Carreiro, Iara Leão Luna de Souza, Joedna Cavalcante Pereira, Luiz Henrique César Vasconcelos, Rafael de Almeida Travassos, Barbara Viviana de Oliveira Santos and Bagnólia Araújo da Silva

    Citation: BMC Complementary and Alternative Medicine 2017 17:514

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  12. Content type: Research article

    Conventional scientific studies had supported the use of polysaccharides and β-glucans from a number of fungi, including Ganoderma lucidum for the treatment of recurrent oral ulceration (ROU). Our aim of the p...

    Authors: Ling Xie, Xiaohong Zhong, Dongbo Liu, Lin Liu and Zhilan Xia

    Citation: BMC Complementary and Alternative Medicine 2017 17:511

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  13. Content type: Research article

    Jia-Wei-Jiao-Tai-Wan (JWJTW), composed of Jiao-Tai-Wan (Cinnamomum cassia and Rhizoma coptidis) and other antidiabetic herbs, including Astragalus membranaceus, Herba Gynostemmatis, Radix Puerariae Lobatae, Foliu...

    Authors: Guang Chen, Xueping Yang, Xiaoyu Yang, Lingli Li, Jinlong Luo, Hui Dong, Lijun Xu, Ping Yi, Kaifu Wang, Xin Zou and Fuer Lu

    Citation: BMC Complementary and Alternative Medicine 2017 17:507

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  14. Content type: Research article

    Atherosclerosis is a chronic vascular inflammatory disease. Since even low-level endotoxemia constitutes a powerful and independent risk factor for the development of atherosclerosis, it is important to find t...

    Authors: Daun Jeon, Seok Joong Kim and Hong Seok Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:508

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  15. Content type: Research article

    Paclitaxel (taxol) is a potent anticancer drug that is used in the treatment of a wide variety of cancerous. In the present study, we identified a taxol derivative named 7-epi-10-deacetyltaxol (EDT) from the cult...

    Authors: Kamalraj Subban, Satpal Singh, Ramesh Subramani, Muthumary Johnpaul and Jayabaskaran Chelliah

    Citation: BMC Complementary and Alternative Medicine 2017 17:504

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  16. Content type: Research article

    In vitro and in vivo studies have shown that Zuo Jin Wan (ZJW), a herbal formula of traditional Chinese medicine (TCM), possessed anticancer properties. However, the underlying mechanism for the action of ZJW ...

    Authors: Jielu Pan, Yangxian Xu, Haiyan Song, Xiqiu Zhou, Zemin Yao and Guang Ji

    Citation: BMC Complementary and Alternative Medicine 2017 17:506

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  17. Content type: Research article

    Stress, regardless of its nature is nowadays recognized as one of the major risk factors for neuropsychiatric diseases, such as mood and anxiety disorders. The brain compared with other organs is more vulnerab...

    Authors: Harquin Simplice Harquin Foyet, Serge Tchinda Deffo, Pascaline Koagne Yewo, Iulia Antioch, Stéphane Zingue, Emmanuel Acha Asongalem, Pierre Kamtchouing and Alin Ciobica

    Citation: BMC Complementary and Alternative Medicine 2017 17:502

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  18. Content type: Research article

    Nonea micrantha Boiss. & Reut . being an unexplored member of Boraginaceae was investigated for GC/MS analysis, acetylcholinesterase (AChE), butyrylcholinest...

    Authors: Muhammad Imran, Farhat Ullah, Muhammad Ayaz, Abdul Sadiq, Muhammad Raza Shah, Muhammad Saeed Jan and Farman Ullah

    Citation: BMC Complementary and Alternative Medicine 2017 17:499

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  19. Content type: Research article

    Recently, we reported high in vitro antibacterial efficacy of Althaea officinalis, Ziziphus jujuba, Cordia latifolia and Thymus vulgaris out of a total 21 plants against wide range of bacteria including MRSA. Thi...

    Authors: Najma Arshad, Arifa Mehreen, Iram Liaqat, Muhammad Arshad and Humera Afrasiab

    Citation: BMC Complementary and Alternative Medicine 2017 17:498

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  20. Content type: Research article

    Aster koraiensis extract (AKE) is a standard dietary herbal supplement. The aim of this study is to investigate the inhibitory effects of AKE on diabetes-induced retinal vascular dysfu...

    Authors: Junghyun Kim, Kyuhyung Jo, Chan-Sik Kim and Jin Sook Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:497

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