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BMC Complementary and Alternative Medicine

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Clinical research

Edited by Holger Cramer, Jianping Liu and Karen Pilkington

This section covers research reporting clinical applications of interventions or resources in the complementary medicine field, including the evaluation of the efficacy and safety of the therapies, clinical trials and systematic reviews/meta-analysis.

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  1. Content type: Research article

    To appraise critically whether published trials of ShenXiong glucose injection for patients with acute ischemic stroke (AIS) are of sufficient quality, and in addition to rate the quality of evidence by using ...

    Authors: Xue-ting Liu, Peng-wei Ren, Le Peng, De-ying Kang, Tian-le Zhang, Shu Wen, Qi Hong and Wen-jie Yang

    Citation: BMC Complementary and Alternative Medicine 2016 16:68

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  2. Content type: Research article

    Of patients undergoing surgery, 22 to 57 % have been reported to be using naturopathic medicines. Several of these medicines have been reported to increase bleeding or enhance the effect of other drugs that in...

    Authors: August Bagge, Ulf Schött and Thomas Kander

    Citation: BMC Complementary and Alternative Medicine 2016 16:64

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  3. Content type: Research article

    The hypertriglyceridemic waist (HW) phenotype has been shown to be strongly associated with metabolic abnormalities; however, to date, no study has reported the prediction of metabolic abnormalities using the ...

    Authors: Bum Ju Lee, Jiho Nam and Jong Yeol Kim

    Citation: BMC Complementary and Alternative Medicine 2016 16:59

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  4. Content type: Study protocol

    Integrative medicine (IM) provides patient-centered care and addresses the full range of physical, emotional, mental, social, spiritual, and environmental influences that affect a person’s health. IM is a “who...

    Authors: Jeffery A. Dusek, Donald I. Abrams, Rhonda Roberts, Kristen H. Griffin, Desiree Trebesch, Rowena J. Dolor, Ruth Q. Wolever, M. Diane McKee and Benjamin Kligler

    Citation: BMC Complementary and Alternative Medicine 2016 16:53

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  5. Content type: Research article

    Symptomatic cervical intervertebral disc herniation (IDH) presenting as neck pain accompanied by arm pain is a common affliction whose prevalence continues to rise, and is a frequent reason for integrative inp...

    Authors: Sang Hyun Baek, Jae Woo Oh, Joon-Shik Shin, Jinho Lee, Yoon Jae Lee, Me-riong Kim, Yong-jun Ahn, Areum Choi, Ki Byung Park, Byung-Cheul Shin, Myeong Soo Lee and In-Hyuk Ha

    Citation: BMC Complementary and Alternative Medicine 2016 16:52

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  6. Content type: Study protocol

    Despite high quality stroke care, decreased sensorimotor function, anxiety and pain often remain one year after stroke which can lead to impaired health and dependence, as well as higher healthcare costs. Touc...

    Authors: Kristina Lämås, Charlotte Häger, Lenita Lindgren, Per Wester and Christine Brulin

    Citation: BMC Complementary and Alternative Medicine 2016 16:50

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  7. Content type: Study protocol

    The purpose of this study is to evaluate the efficacy and safety of myofascial-meridian release acupuncture (MMRA) in the treatment of chronic neck pain compared with sham acupuncture.

    Authors: Seunghoon Lee, Dongwoo Nam, Jungtae Leem, Gajin Han, Seungmin Lee and Junhee Lee

    Citation: BMC Complementary and Alternative Medicine 2016 16:45

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  8. Content type: Study protocol

    Although various placebo acupuncture devices have been developed and used in acupuncture research, there is controversy concerning whether these devices really serve as appropriate placebos for control groups.

    Authors: Jungtae Leem, Jimin Park, Gajin Han, Seulgi Eun, Meena M. Makary, Kyungmo Park, Junhee Lee and Sanghoon Lee

    Citation: BMC Complementary and Alternative Medicine 2016 16:43

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  9. Content type: Study protocol

    Chronic cough, defined it lasts more than 8 weeks. The symptom is common, but highly troublesome, and it reduces quality of life. Despite much effort to develop a protocol for diagnosis and treatment of chroni...

    Authors: Kwan-Il Kim, Seungwon Shin, Kyuseok Kim and Junhee Lee

    Citation: BMC Complementary and Alternative Medicine 2016 16:46

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  10. Content type: Research article

    Probiotics have rarely been studied in young healthy infants from low-income countries. This phase I study investigated the safety and acceptability of two probiotics in Bangladesh.

    Authors: Yana Emmy Hoy-Schulz, Kaniz Jannat, Thomas Roberts, Saira Husain Zaidi, Leanne Unicomb, Stephen Luby and Julie Parsonnet

    Citation: BMC Complementary and Alternative Medicine 2016 16:44

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  11. Content type: Research article

    Transcutaneous acupoint electrical stimulation (TAES) as a needleless acupuncture has the same effect like traditional manual acupuncture. The combination of TAES and anesthesia has been proved valid in enhanc...

    Authors: Xing Liu, Jing Wang, Baoguo Wang, Ying Hua Wang, Qinglei Teng, Jiaqing Yan, Shuangyan Wang and You Wan

    Citation: BMC Complementary and Alternative Medicine 2016 16:33

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  12. Content type: Study protocol

    Due to increasing interest from acne patients concerned about the side effects associated with conventional therapies, complementary and alternative medicine (CAM) has been suggested as a new therapeutic modal...

    Authors: Kyuseok Kim, Kwan-Il Kim and Junhee Lee

    Citation: BMC Complementary and Alternative Medicine 2016 16:21

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  13. Content type: Study protocol

    The treatment of low back pain is very challenging due to the recurrent nature of the problem. It is believed that traditional Malay massage helps to relieve such back pain but there is a lack of scientific ev...

    Authors: Nurhanisah Sejari, Kamaria Kamaruddin, Kalavathy Ramasamy, Siong Meng Lim, Chin Fen Neoh and Long Chiau Ming

    Citation: BMC Complementary and Alternative Medicine 2016 16:16

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  14. Content type: Research article

    Nausea and vomiting in pregnancy (NVP) and hyperemesis gravidarum (HG) have a significant impact on quality of life. Medication to relieve symptoms of NVP and HG are available but pregnant women and their care...

    Authors: Els Van den Heuvel, Maria Goossens, Hilde Vanderhaegen, Hai Xia Sun and Frank Buntinx

    Citation: BMC Complementary and Alternative Medicine 2016 16:13

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  15. Content type: Research article

    Sailuotong (SLT) is a standardised herbal medicine formula consisting of Panax ginseng, Ginkgo biloba, and Crocus sativus, and has been designed to enhance cognitive and cardiovascular function.

    Authors: Genevieve Z. Steiner, Alan Yeung, Jian-Xun Liu, David A. Camfield, Frances M. de Blasio, Andrew Pipingas, Andrew B. Scholey, Con Stough and Dennis H. Chang

    Citation: BMC Complementary and Alternative Medicine 2016 16:15

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  16. Content type: Research article

    It is important that potential study participants are appropriately informed and understand what is involved with their research participation. A few studies have examined study participants’ understanding of ...

    Authors: Caroline A. Smith and Sarah Fogarty

    Citation: BMC Complementary and Alternative Medicine 2016 16:10

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  17. Content type: Research article

    Functional dyspepsia (FD), which is a very common disorder worldwide, is known to be caused by multiple factors including environmental and genetic factors. Sasang constitutional medicine (SCM) is a component ...

    Authors: Yoon Jeong Kim, Yo Chan Ahn and Chang Gue Son

    Citation: BMC Complementary and Alternative Medicine 2015 15:150

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  18. Content type: Research article

    Cystic fibrosis (CF) leads to advanced lung disease despite aggressive care. Persistent inflammation and oxidative stress contribute to exacerbations and disease progression. Flaxseed (FS), a dietary botanical...

    Authors: Jason B Turowski, Ralph A Pietrofesa, John A Lawson, Melpo Christofidou-Solomidou and Denis Hadjiliadis

    Citation: BMC Complementary and Alternative Medicine 2015 15:148

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  19. Content type: Research article

    Dementia is a prevalent neurodegenerative disorder affecting an estimated 24.3 million people across the globe. The burden on those caring for people with dementia is substantial, with widespread implications ...

    Authors: Matthew J. Leach, Andrew Francis and Tahereh Ziaian

    Citation: BMC Complementary and Alternative Medicine 2015 15:145

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  20. Content type: Research article

    Chronic tension-type headache (CTTH) is characterized by almost daily headaches and central sensitization, for which electroacupuncture (EA) might be effective. The central nervous system (CNS) plasticity can ...

    Authors: Mônica Chassot, Jairo Alberto Dussan-Sarria, Francislea Cristina Sehn, Alícia Deitos, Andressa de Souza, Rafael Vercelino, Iraci LS Torres, Felipe Fregni and Wolnei Caumo

    Citation: BMC Complementary and Alternative Medicine 2015 15:144

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