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Clinical research

Edited by Holger Cramer, Jianping Liu and Karen Pilkington

This section covers research reporting clinical applications of interventions or resources in the complementary medicine field, including the evaluation of the efficacy and safety of the therapies, clinical trials and systematic reviews/meta-analysis.

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  1. Content type: Research article

    Cardiovascular diseases are a main cause of mortality worldwide. Spa bathing and immersion in thermoneutral water (ITW) have a long history in the treatment of cardiovascular risk factors.

    Authors: Johannes Naumann, Catharina Sadaghiani, Nina Bureau, Stefan Schmidt and Roman Huber

    Citation: BMC Complementary and Alternative Medicine 2016 16:250

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  2. Content type: Research article

    Tangshen Formula (TSF) is a traditional Chinese medicine for the treatment of diabetic kidney disease (DKD). Liver-type fatty acid binding protein (L-FABP) is expressed in various tissues, including the kidney...

    Authors: Xin Yang, Bingxuan Zhang, Xiaoguang Lu, Meihua Yan, Yumin Wen, Tingting Zhao and Ping Li

    Citation: BMC Complementary and Alternative Medicine 2016 16:246

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  3. Content type: Research article

    Most subjects regain weight after weight loss due to compensatory adaptations finalized to maintain stable body energy stores. Green tea (GT) preparations, which help maintain energy expenditure while dieting ...

    Authors: Luisa Gilardini, Lucia Pasqualinotto, Francesco Di Pierro, Paolo Risso and Cecilia Invitti

    Citation: BMC Complementary and Alternative Medicine 2016 16:233

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  4. Content type: Research article

    This study aimed to investigate the effect of acupuncture administered immediately following a graded exercise test (GXT) on physiological measures of recovery and determine if instruction (expectancy) affecte...

    Authors: Paola Urroz, Ben Colagiuri, Caroline A. Smith, Alan Yeung and Birinder S. Cheema

    Citation: BMC Complementary and Alternative Medicine 2016 16:227

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  5. Content type: Research article

    Acupuncture is not considered a conventional therapy for post-stroke sequelae but it might have some additional positive effects on early rehabilitation. We conducted this trial to determine whether acupunctur...

    Authors: Lifang Chen, Jianqiao Fang, Ruijie Ma, Xudong Gu, Lina Chen, Jianhua Li and Shouyu Xu

    Citation: BMC Complementary and Alternative Medicine 2016 16:226

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  6. Content type: Research article

    Increased cellular ATP levels have the potential to enhance athletic performance. A proprietary blend of ancient peat and apple extracts has been supposed to increase ATP production. Therefore, the purpose of ...

    Authors: Jordan M. Joy, Roxanne M. Vogel, Jordan R. Moon, Paul H. Falcone, Matt M. Mosman, Zbigniew Pietrzkowski, Tania Reyes and Michael P. Kim

    Citation: BMC Complementary and Alternative Medicine 2016 16:224

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  7. Content type: Research article

    Primary insomnia is a widespread and refractory disease. Moxibustion therapy for insomnia shows some advantages compared with conventional therapies. This systematic review and meta-analysis of randomized cont...

    Authors: Yu-Jiao Sun, Jia-Min Yuan and Zhi-Min Yang

    Citation: BMC Complementary and Alternative Medicine 2016 16:217

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  8. Content type: Research article

    Tripterygium wilfordii Hook F (TwHF), a medicinal plant that has been widely used in Chinese traditional medicine, is proven effective for treating rheumatoid arthritis (RA), but its c...

    Authors: Hai-Long Wang, Quan Jiang, Xing-Hua Feng, Hua-Dong Zhang, Lin Ge, Cheng-Gui Luo, Xun Gong and Bo Li

    Citation: BMC Complementary and Alternative Medicine 2016 16:215

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  9. Content type: Research article

    Qili Qiangxin capsule is a standardized Chinese herbal treatment that is commonly used in China for heart failure (HF) alongside conventional medical care. In 2014, Chinese guidelines for the treatment of chro...

    Authors: Jin Sun, Kang Zhang, Wen-Jing Xiong, Guo-Yan Yang, Yun-Jiao Zhang, Cong-Cong Wang, Lily Lai, Mei Han, Jun Ren, George Lewith and Jian-Ping Liu

    Citation: BMC Complementary and Alternative Medicine 2016 16:201

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  10. Content type: Research article

    Mesenteric phlebosclerosis (MP) is a disease characterized by fibrotic change or calcification of the mesenteric vein. Recently, there has been an increase in case reports of MP related to herbal medicine usag...

    Authors: Yutaka Nagata, Tetsuo Watanabe, Kazuhiko Nagasaka, Masaaki Yamada, Masafumi Murai, Sunao Takeuchi, Mai Murase, Toshinori Yazaki, Takayuki Murase, Kenichi Komatsu, Machiko Kaizuka, Mika Sano, Koji Asano, Chikao Ando and Norihide Taniuchi

    Citation: BMC Complementary and Alternative Medicine 2016 16:207

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  11. Content type: Research article

    The use of Complementary and Alternative Medicine (CAM) has been increasing over the years. A recent review of adverse event reports (AERs) associated with CAM in Singapore found a notable number of AERs submi...

    Authors: Desmond Chun Hwee Teo, Patricia Suet Leng Ng, Siew Har Tan, Adena Theen Lim, Dorothy Su Lin Toh, Sui Yung Chan and Han Hui Cheong

    Citation: BMC Complementary and Alternative Medicine 2016 16:192

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  12. Content type: Study protocol

    Cerebral palsy leads to many complications as well as delayed motor development, and early intensive rehabilitation in infancy, which is based on the theory of brain plasticity, is emphasized. In addition to c...

    Authors: Jeong-Eun Yoo, Young-Ju Yun, Yong-Beom Shin, Nam-kwen Kim, Soo-Yeon Kim, Myung-Jun Shin and Sun-ae Yu

    Citation: BMC Complementary and Alternative Medicine 2016 16:172

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  13. Content type: Research article

    Hitherto no study has been published on the effect of the adjunctive administration of essential oils following scaling and root planing (SRP). This study describes the effect of a mouthrinse consisting of ess...

    Authors: Mohammad Fallah Azad, Andreas Schwiertz and Holger F. R. Jentsch

    Citation: BMC Complementary and Alternative Medicine 2016 16:171

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  14. Content type: Research article

    Muscle damage induced by unaccustomed or eccentric exercise results in delayed onset vascular stiffening. We tested the hypothesis that a 7-day supplementation of panax ginseng and salvia miltiorrhiza prior to an...

    Authors: Hsin-Fu Lin, Kang Tung, Chun-Chung Chou, Ching-Che Lin, Jaung-Geng Lin and Hirofumi Tanaka

    Citation: BMC Complementary and Alternative Medicine 2016 16:168

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  15. Content type: Research article

    Clinical history-taking can be employed as a standardized approach to elucidate the use of herbal medicines and their linked suspected adverse drug reactions (ADRs) among hospitalized patients. We sought to id...

    Authors: Ronald Kiguba, Sam Ononge, Charles Karamagi and Sheila M. Bird

    Citation: BMC Complementary and Alternative Medicine 2016 16:145

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  16. Content type: Research article

    During Flotation-REST a person is floating inside a quiet and dark tank, filled with heated salt saturated water. Deep relaxation and beneficial effects on e.g. stress, sleep difficulties, anxiety and depressi...

    Authors: Kristoffer Jonsson and Anette Kjellgren

    Citation: BMC Complementary and Alternative Medicine 2016 16:108

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  17. Content type: Case report

    Immune thrombocytopenia (ITP) is a hematological disorder with an isolated decrease in number of circulating platelets. Bee venom therapy (BVT) is a form of alternative medicine. It is still being practiced in...

    Authors: Mohammad Adel Abdulsalam, Bader Esmael Ebrahim and Ahmad Jasem Abdulsalam

    Citation: BMC Complementary and Alternative Medicine 2016 16:107

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  18. Content type: Research article

    Patients who sustain a motor vehicle accident may experience long-term distress, even if they are uninjured or only slightly injured. There is a risk of neglecting patients with minor or no physical injuries, ...

    Authors: Fanny Airosa, Maria Arman, Tobias Sundberg, Gunnar Öhlén and Torkel Falkenberg

    Citation: BMC Complementary and Alternative Medicine 2016 16:106

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  19. Content type: Study protocol

    Although higher habitual soy intake is associated with lower blood pressure (BP) and stroke incidence, clinical trials using soy protein or isoflavones on cardiovascular risks yielded inconsistent results. The...

    Authors: Zhao-min Liu, Suzanne C. Ho, Yu-ming Chen, Yao Jie Xie, Zhi-guan Huang and Wen-hua Ling

    Citation: BMC Complementary and Alternative Medicine 2016 16:89

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