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Clinical research

Edited by Holger Cramer, Jianping Liu and Karen Pilkington

This section covers research reporting clinical applications of interventions or resources in the complementary medicine field, including the evaluation of the efficacy and safety of the therapies, clinical trials and systematic reviews/meta-analysis.

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  1. Content type: Research article

    Current clinical practices used to functionally classify heart failure (HF) are time-consuming, expensive, or require complex calculations. This study aimed to design an inquiry list from the perspective of tr...

    Authors: Tieh-Cheng Fu, Yi-Chung Lin, Ching-Mao Chang, Wei-Ling Chou, Pei-Hsun Yuan, Min-Hui Liu, Chao-Hung Wang, Juei-Chao Chen, Hen-Hong Chang and Tai-Long Pan

    Citation: BMC Complementary and Alternative Medicine 2016 16:342

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  2. Content type: Research article

    We aimed to evaluate the effect of an 8-week yoga intervention on the shoulder and spinal actions of women with breast cancer-related arm lymphoedema.

    Authors: Annette Loudon, Tony Barnett, Neil Piller, Maarten A. Immink, Denis Visentin and Andrew D. Williams

    Citation: BMC Complementary and Alternative Medicine 2016 16:343

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  3. Content type: Research article

    Virus-induced dendritic cells (DCs) functional deficiency leads to sub-optimal initiation of adaptive immune responses and consequently chronic infection establishment. The present study reports an advanced he...

    Authors: Doaa A. Ghareeb, Eiman H. Elwakeel, Rowaida Khalil, Mina S. Aziz and Maha A. El demellawy

    Citation: BMC Complementary and Alternative Medicine 2016 16:325

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  4. Content type: Research article

    Diabetes mellitus (DM) is a hypercoagulable state and is associated with highly increased risk of vascular complications. In the theory of traditional Chinese medicine (TCM), these vascular complications are c...

    Authors: Po-Chi Hsu, Yu-Chuen Huang, John Y. Chiang, Hen-Hong Chang, Pei-Yung Liao and Lun-Chien Lo

    Citation: BMC Complementary and Alternative Medicine 2016 16:324

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  5. Content type: Research article

    Antrodia cinnamomea (AC) is a popular medicinal mushroom in Taiwan that has been widely used for treatment of various cancers. Few clinical studies have reported its application and ef...

    Authors: Ming-Yen Tsai, Yu-Chiang Hung, Yen-Hao Chen, Yung-Hsiang Chen, Yu-Chuen Huang, Chao-Wei Kao, Yu-Li Su, Hsien-Hsueh Elley Chiu and Kun-Ming Rau

    Citation: BMC Complementary and Alternative Medicine 2016 16:322

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  6. Content type: Research article

    Self-report measures indicate that Yoga practices are perceived to reduce stress; however, molecular mechanisms through which YB affects stress are just beginning to be understood. While invasive sampling such...

    Authors: Waleed O. Twal, Amy E. Wahlquist and Sundaravadivel Balasubramanian

    Citation: BMC Complementary and Alternative Medicine 2016 16:294

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  7. Content type: Research article

    With an estimated 65 million Diabetes Mellitus (DM) patients, India ranks second in the world in terms of DM burden. The emphasis of current medical practice has been on pharmacotherapy but, despite the best c...

    Authors: Srinivas Bairy, Ajay M. V. Kumar, MSN Raju, Shanta Achanta, Balaji Naik, Jaya P. Tripathy and Rony Zachariah

    Citation: BMC Complementary and Alternative Medicine 2016 16:290

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  8. Content type: Research article

    Despite the increasing number and variety of antiepileptic drugs, nearly 30 % of epileptic patients who receive appropriate medical attention have persisting seizures. Anticonvulsant activity has been demonstr...

    Authors: Germain Sotoing Taiwe, Bernard Dabole, Thierry Bang Tchoya, Joseph Renaud Menanga, Paul Désiré Djomeni Dzeufiet and Michel De Waard

    Citation: BMC Complementary and Alternative Medicine 2016 16:285

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  9. Content type: Research article

    Chronic pain can alter the autonomic balance with increased sympathetic activity reflected in altered heart rate variability (HRV). It has been proposed that yoga can be useful to correct the autonomic imbalan...

    Authors: Shirley Telles, Sachin Kumar Sharma, Ram Kumar Gupta, Abhishek Kumar Bhardwaj and Acharya Balkrishna

    Citation: BMC Complementary and Alternative Medicine 2016 16:279

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  10. Content type: Research article

    The purpose of this study is to investigate cardiovascular benefits of juices obtained from two commonly consumed fruits in Thailand, Pachyrhizus erosus, L. (yam bean) and Psidium guajava, L. (guava), by examinin...

    Authors: Thitiporn Thaptimthong, Thitima Kasemsuk, Nathawut Sibmooh and Supeenun Unchern

    Citation: BMC Complementary and Alternative Medicine 2016 16:269

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  11. Content type: Research article

    Osteoarthritic knee (OA knee) is a common condition in the elderly. Exploration of non-invasive complementary therapies for OA knee is warranted given the limitations of pharmacologic therapies. Auriculotherap...

    Authors: Lorna K. P. Suen, Chao Hsing Yeh and Simon K. W. Yeung

    Citation: BMC Complementary and Alternative Medicine 2016 16:257

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    The Erratum to this article has been published in BMC Complementary and Alternative Medicine 2016 16:391

  12. Content type: Research article

    Cardiovascular diseases are a main cause of mortality worldwide. Spa bathing and immersion in thermoneutral water (ITW) have a long history in the treatment of cardiovascular risk factors.

    Authors: Johannes Naumann, Catharina Sadaghiani, Nina Bureau, Stefan Schmidt and Roman Huber

    Citation: BMC Complementary and Alternative Medicine 2016 16:250

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  13. Content type: Research article

    Tangshen Formula (TSF) is a traditional Chinese medicine for the treatment of diabetic kidney disease (DKD). Liver-type fatty acid binding protein (L-FABP) is expressed in various tissues, including the kidney...

    Authors: Xin Yang, Bingxuan Zhang, Xiaoguang Lu, Meihua Yan, Yumin Wen, Tingting Zhao and Ping Li

    Citation: BMC Complementary and Alternative Medicine 2016 16:246

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  14. Content type: Research article

    Most subjects regain weight after weight loss due to compensatory adaptations finalized to maintain stable body energy stores. Green tea (GT) preparations, which help maintain energy expenditure while dieting ...

    Authors: Luisa Gilardini, Lucia Pasqualinotto, Francesco Di Pierro, Paolo Risso and Cecilia Invitti

    Citation: BMC Complementary and Alternative Medicine 2016 16:233

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  15. Content type: Research article

    This study aimed to investigate the effect of acupuncture administered immediately following a graded exercise test (GXT) on physiological measures of recovery and determine if instruction (expectancy) affecte...

    Authors: Paola Urroz, Ben Colagiuri, Caroline A. Smith, Alan Yeung and Birinder S. Cheema

    Citation: BMC Complementary and Alternative Medicine 2016 16:227

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  16. Content type: Research article

    Acupuncture is not considered a conventional therapy for post-stroke sequelae but it might have some additional positive effects on early rehabilitation. We conducted this trial to determine whether acupunctur...

    Authors: Lifang Chen, Jianqiao Fang, Ruijie Ma, Xudong Gu, Lina Chen, Jianhua Li and Shouyu Xu

    Citation: BMC Complementary and Alternative Medicine 2016 16:226

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  17. Content type: Research article

    Increased cellular ATP levels have the potential to enhance athletic performance. A proprietary blend of ancient peat and apple extracts has been supposed to increase ATP production. Therefore, the purpose of ...

    Authors: Jordan M. Joy, Roxanne M. Vogel, Jordan R. Moon, Paul H. Falcone, Matt M. Mosman, Zbigniew Pietrzkowski, Tania Reyes and Michael P. Kim

    Citation: BMC Complementary and Alternative Medicine 2016 16:224

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  18. Content type: Research article

    Tripterygium wilfordii Hook F (TwHF), a medicinal plant that has been widely used in Chinese traditional medicine, is proven effective for treating rheumatoid arthritis (RA), but its c...

    Authors: Hai-Long Wang, Quan Jiang, Xing-Hua Feng, Hua-Dong Zhang, Lin Ge, Cheng-Gui Luo, Xun Gong and Bo Li

    Citation: BMC Complementary and Alternative Medicine 2016 16:215

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