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BMC Complementary and Alternative Medicine

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Clinical research

Edited by Holger Cramer, Jianping Liu and Karen Pilkington

This section covers research reporting clinical applications of interventions or resources in the complementary medicine field, including the evaluation of the efficacy and safety of the therapies, clinical trials and systematic reviews/meta-analysis.

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  1. Content type: Research article

    Several studies have used placebo acupuncture methods in recent years as a way for blinding therapeutic effect of acupuncture, however placebo method selection has not followed enough methodological criteria t...

    Authors: Leonardo Yung dos Santos Maciel, Paula Michele dos Santos Leite, Mauricio Lima Poderoso Neto, Andreza Carvalho Rabelo Mendonça, Carla Carolina Alves de Araujo, Jersica da Hora Santos Souza and Josimari Melo DeSantana

    Citation: BMC Complementary and Alternative Medicine 2016 16:518

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  2. Content type: Research article

    Electroacupuncture (EA), as an extension technique of acupuncture based on traditional acupuncture combined with modern electrotherapy, is commonly used for stroke in clinical treatment and researches. However...

    Authors: Jing-jing Wei, Wen-ting Yang, Su-bing Yin, Chen Wang, Yan Wang and Guo-qing Zheng

    Citation: BMC Complementary and Alternative Medicine 2016 16:512

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  3. Content type: Research article

    Ao-dake-humi is a traditional Japanese bamboo foot stimulator consisting of a half-pipe-shaped step made of bamboo used to stimulate the foot by stepping on it, and is commonly used to...

    Authors: Tomonori Minagawa, Tetsuichi Saitou, Toshiro Suzuki, Takahisa Domen, Hitoshi Yokoyama, Masakuni Ishikawa, Shiro Hirakata, Takashi Nagai, Masaki Nakazawa, Teruyuki Ogawa and Osamu Ishizuka

    Citation: BMC Complementary and Alternative Medicine 2016 16:513

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  4. Content type: Study protocol

    Prednisone plus azathioprine is considered the mainstay of therapy in the current recommendations for autoimmune hepatitis (AIH). However, it does not provide good benefits for AIH patients because of its seri...

    Authors: Xiao-ling Chi, Huan-ming Xiao, Yu-bao Xie, Gao-shu Cai, Jun-min Jiang, Guang-jun Tian, Mei-jie Shi, Shu-duo Wu, Peng-tao Zhao and Hui-jun Chen

    Citation: BMC Complementary and Alternative Medicine 2016 16:505

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  5. Content type: Research article

    In the author’s earlier in vitro investigation, a combination of 0.25 mg/ml green tea and 7.82 mg/ml Salvadora persica L. aqueous extracts was found to exhibit significant synergistic anti-bacterial and anti-adhe...

    Authors: Hayder Raad Abdulbaqi, Wan Harun Himratul-Aznita and Nor Adinar Baharuddin

    Citation: BMC Complementary and Alternative Medicine 2016 16:493

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  6. Content type: Research article

    Manual muscle testing (MMT) is a non-invasive assessment tool used by a variety of health care providers to evaluate neuromusculoskeletal integrity, and muscular strength in particular. In one form of MMT call...

    Authors: Anne M. Jensen, Richard J. Stevens and Amanda J. Burls

    Citation: BMC Complementary and Alternative Medicine 2016 16:492

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  7. Content type: Study protocol

    Coronary artery bypass graft surgery (CABG) is an effective and widespread coronary revascularisation technique, nevertheless there are a number of long-term postoperative complications from which patients can...

    Authors: Gert Roncada

    Citation: BMC Complementary and Alternative Medicine 2016 16:482

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  8. Content type: Research article

    Hashimoto’s thyroiditis is an autoimmune disorder and the most common cause of hypothyroidism. The use of Nigella sativa, a potent herbal medicine, continues to increase worldwide as an alternative treatment o...

    Authors: Mahdieh Abbasalizad Farhangi, Parvin Dehghan, Siroos Tajmiri and Mehran Mesgari Abbasi

    Citation: BMC Complementary and Alternative Medicine 2016 16:471

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  9. Content type: Research article

    The effect and safety of catgut implantation at acupoints o treat allergic rhinitis (ICD-10 code J30.4) remain controversial. Here, we used a sham catgut implantation group to determine whether catgut implanta...

    Authors: Xinrong Li, Yang Liu, Qinxiu Zhang, Nan Xiang, Miao He, Juan Zhong, Qing Chen and Xiaopei Wang

    Citation: BMC Complementary and Alternative Medicine 2016 16:454

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  10. Content type: Research article

    The theory of traditional Chinese medicine (TCM) constitution involves genetic characteristics, psychological factors, organ functions, and many other aspects. Studies have shown that TCM constitution is assoc...

    Authors: Yi Liu, Ting Pan, Wenjing Zou, Ye Sun, Yun Cai, Rui Wang, Pingping Han, Zhe Zhang, Qunying He and Feng Ye

    Citation: BMC Complementary and Alternative Medicine 2016 16:451

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  11. Content type: Research article

    Postoperative nausea and vomiting (PONV) is one of the most common postoperative complications of general anesthesia in pediatrics. Aromatherapy has been shown to be effective in treating PONV in adults. Given...

    Authors: Mathew B. Kiberd, Suzanne K. Clarke, Jill Chorney, Brandon d’Eon and Stuart Wright

    Citation: BMC Complementary and Alternative Medicine 2016 16:450

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  12. Content type: Research article

    Danlou tablets, a patented Chinese Medicine, have been long approved for the treatment of ischemic heart disease in China. While numerous empirical observations suggested Danlou tablets could decrease frequenc...

    Authors: Shuai Mao, Lei Wang, Wenwei Ouyang, Yuanshen Zhou, Jianyong Qi, Liheng Guo, Minzhou Zhang and Aleksander Hinek

    Citation: BMC Complementary and Alternative Medicine 2016 16:447

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  13. Content type: Study protocol

    Acupuncture is beneficial for controlling chemotherapy-induced nausea and vomiting (CINV). However, the effect of different acupoint combinations on controlling CINV remains unknown. This study aims to compare...

    Authors: Lili Gao, Bo Chen, Qiwen Zhang, Tianyi Zhao, Bo Li, Tao Sha, Jinxin Zou, Yongming Guo, Xingfang Pan and Yi Guo

    Citation: BMC Complementary and Alternative Medicine 2016 16:441

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  14. Content type: Study protocol

    Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) affects many adult men worldwide. The currently available therapies offer little or no proven benefit for CP/CPPS. We designed this study to assess th...

    Authors: Zongshi Qin, Zhiwei Zang, Jiani Wu, Jing Zhou and Zhishun Liu

    Citation: BMC Complementary and Alternative Medicine 2016 16:440

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  15. Content type: Research article

    Allergic rhinitis is regarded as an imbalanced Th1/Th2 cell-mediated response. The present study used microarray analysis to compare gene expression levels between allergic rhinitis patients before and after a...

    Authors: Horng-Sheng Shiue, Yun-Shien Lee, Chi-Neu Tsai and Hen-Hong Chang

    Citation: BMC Complementary and Alternative Medicine 2016 16:436

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  16. Content type: Study protocol

    Caregiving can be stressful, potentially creating physical and psychological strain. Substantial evidence has shown that family caregivers suffer from significant health problems arising from the demands of ca...

    Authors: Agnes Tiwari, Lixing Lao, Amy Xiao-Min Wang, Denise Shuk Ting Cheung, Mike Ka Pui So, Doris Sau Fung Yu, Terry Yat Sang Lum, Helina Yin King Yuk Fung, Jerry Wing Fai Yeung and Zhang-Jin Zhang

    Citation: BMC Complementary and Alternative Medicine 2016 16:424

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  17. Content type: Study protocol

    Irritable bowel syndrome (IBS) is a worldwide disease with high morbidity. The effect of current treatment with Western medicine is not satisfactory. Although moxibustion treatment is widely used for gastroint...

    Authors: Chunhui Bao, Jingzhi Zhang, Jinmei Liu, Huirong Liu, Luyi Wu, Yin Shi, Jing Li, Zhihai Hu, Yongzheng Dong, Siyao Wang, Xiaoqing Zeng and Huangan Wu

    Citation: BMC Complementary and Alternative Medicine 2016 16:408

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  18. Content type: Study protocol

    Virgin olive oil, a recognized healthy food, cannot be consumed in great quantities. We aim to assess in humans whether an optimized virgin olive oil with high phenolic content (OVOO, 429 mg/Kg) and a function...

    Authors: Sara Biel, Maria-Dolores Mesa, Rafael de la Torre, Juan-Antonio Espejo, Jose-Ramón Fernández-Navarro, Montserrat Fitó, Estefanía Sánchez-Rodriguez, Carmen Rosa, Rosa Marchal, Juan de Dios Alche, Manuela Expósito, Manuel Brenes, Beatriz Gandul, Miguel Angel Calleja and María-Isabel Covas

    Citation: BMC Complementary and Alternative Medicine 2016 16:404

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  19. Content type: Research article

    In Japanese Kampo medical practice, suidoku (fluid disturbance) is one of the most important concepts for selecting the proper medication. Suidoku is an excessive or uneven distribution of fluid that is indica...

    Authors: Aya Murakami, Daisuke Kobayashi, Toshio Kubota, Niina Zukeyama, Haru Mukae, Norihiro Furusyo, Mosaburo Kainuma and Takao Shimazoe

    Citation: BMC Complementary and Alternative Medicine 2016 16:405

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