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BMC Complementary and Alternative Medicine

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Clinical research

Edited by Holger Cramer, Jianping Liu and Karen Pilkington

This section covers research reporting clinical applications of interventions or resources in the complementary medicine field, including the evaluation of the efficacy and safety of the therapies, clinical trials and systematic reviews/meta-analysis.

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  1. Content type: Study protocol

    Bruxism is a repetitive activity that causes tooth wear, audible sounds, and discomfort. Preventive measures have been studied for conditions that can exert a negative influence on physiological development in...

    Authors: Mônica da Consolação Canuto Salgueiro, Carolina Carvalho Bortoletto, Anna Carolina RattoTempestini Horliana, Ana Carolina Costa Mota, Lara Jansiski Motta, Pamella de Barros Motta, Raquel Agnelli MesquitaFerrari, Kristianne Porta Santos Fernandes and Sandra Kalil Bussadori

    Citation: BMC Complementary and Alternative Medicine 2017 17:391

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  2. Content type: Research article

    YY-312 is a herbal extract powder from Imperata cylindrica Beauvois, Citrus unshiu Markovich, and Evodia officinalis Dode, which have health promoting effects, including body fat reduction. We aimed to evaluate t...

    Authors: Young-Gyu Cho, Ji-Hye Jung, Jae-Heon Kang, Jin Soo Kwon, Seung Pil Yu and Tae Gon Baik

    Citation: BMC Complementary and Alternative Medicine 2017 17:375

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  3. Content type: Study protocol

    In the treatment of functional dyspepsia, the placebo effect has been reported to be high, and the influence of the patient-practitioner relationship may be a major component of this effect. The specific and n...

    Authors: Seok-Jae Ko, Jae-Woo Park, Jungtae Leem, Ted J. Kaptchuk, Vitaly Napadow, Braden Kuo, Jessica Gerber, Laurie Dimisko, Inkwon Yeo, Junhee Lee and Jinsung Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:363

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  4. Content type: Research article

    Dogs are the most common companion animal, and therefore not surprisingly a popular choice for animal-assisted interventions. Dog-assisted interventions are increasingly used in healthcare. The aim of the revi...

    Authors: Martina Lundqvist, Per Carlsson, Rune Sjödahl, Elvar Theodorsson and Lars-Åke Levin

    Citation: BMC Complementary and Alternative Medicine 2017 17:358

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  5. Content type: Study protocol

    Stroke presents a serious health problem in China. Despite progresses made in recent years, there is still a lack of effective treatments for acute ischemic stroke (AIS) in clinical practices.

    Authors: Weiping Sun, Qianhua Ou, Zhijun Zhang, Jiazhi Qu and Yining Huang

    Citation: BMC Complementary and Alternative Medicine 2017 17:357

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  6. Content type: Study protocol

    Cancer-related fatigue is one of the most common symptoms experienced by cancer patients, and it diminishes their quality of life. However, there is currently no confirmed standard treatment for cancer-related...

    Authors: Mikyung Kim, Jung-Eun Kim, Hye-Yoon Lee, Ae-Ran Kim, Hyo-Ju Park, O-Jin Kwon, Eun-Jung Kim, Yeon-Cheol Park, Byung-Kwan Seo, Jung Hyo Cho and Joo-Hee Kim

    Citation: BMC Complementary and Alternative Medicine 2017 17:353

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  7. Content type: Research article

    The psychophysical responses induced by verum acupuncture are characterized by a constellation of unique subjective sensory responses commonly termed De Qi. Furthermore, a variety of sham interventions have be...

    Authors: Shohreh Razavy, Marcus Gadau, Shi Ping Zhang, Fu Chun Wang, Sergio Bangrazi, Christine Berle, Mahrita Harahap, Tie Li, Wei Hong Li and Christopher Zaslawski

    Citation: BMC Complementary and Alternative Medicine 2017 17:348

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  8. Content type: Research article

    Pain is a common symptom in cancer patients. Acupuncture is a suggested treatment for a wide range of clinical conditions, usually for its beneficial effects on pain control. Si guan xue (the four points) have be...

    Authors: To-Yi Lam, Li-Ming Lu, Wai-Man Ling and Li-Zhu Lin

    Citation: BMC Complementary and Alternative Medicine 2017 17:335

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  9. Content type: Research article

    Quality of life has become an important aspect in the measurement of the health of an individual as the population ages. Rhythm-centred music making (RMM) has been shown to improve physical, psychological and ...

    Authors: Angela Frances Yap, Yu Heng Kwan, Chuen Seng Tan, Syed Ibrahim and Seng Bin Ang

    Citation: BMC Complementary and Alternative Medicine 2017 17:311

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  10. Content type: Research article

    Traditional Chinese medicine (TCM) has a long history in the treatment of psoriasis vulgaris. We aimed to evaluate the clinical efficacy and safety of Chinese herbal Pulian ointment in treating psoriasis vulga...

    Authors: Nuo Li, Wenbin Zhao, Jianmin Xing, Jianping Liu, Guangzhong Zhang, Yunbi Zhang, Yuanwen Li, Wali Liu, Fei Shi and Yanping Bai

    Citation: BMC Complementary and Alternative Medicine 2017 17:264

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  11. Content type: Research article

    Despite advances in the treatment of depression, one-third of depressed patients fail to respond to conventional antidepressant medication. There is a need for more effective treatments with fewer side effects. T...

    Authors: Johannes Naumann, Julian Grebe, Sonja Kaifel, Tomas Weinert, Catharina Sadaghiani and Roman Huber

    Citation: BMC Complementary and Alternative Medicine 2017 17:172

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  12. Content type: Research article

    Only a small number of articles have investigated the relationship between mindfulness-based interventions (MBIs) and biomarkers. The aim of this systematic review was to study the effect of MBIs on specific b...

    Authors: Kenji Sanada, Marta Alda Díez, Montserrat Salas Valero, María C. Pérez-Yus, Marcelo M. P. Demarzo, Jesús Montero-Marín, Mauro García-Toro and Javier García-Campayo

    Citation: BMC Complementary and Alternative Medicine 2017 17:125

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  13. Content type: Study protocol

    Thalamic hemorrhage (TH) is a neurological insult with a high rate of morbidity and mortality. Moderate TH (10–30 ml) accounts for more than half of all TH. Treatment remains controversial. The role of acupunc...

    Authors: Chengwei Wang, Chao You, Lu Ma, Mengyue Liu, Meng Tian and Ning Li

    Citation: BMC Complementary and Alternative Medicine 2017 17:112

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  14. Content type: Research article

    Qianggu Capsule, a Chinese patent medicine, has been widely applied in the clinical practice of primary osteoporosis (POP) in recent years. This study aims to summarize the effectiveness and safety of Qianggu ...

    Authors: Xu Wei, Aili Xu, Hao Shen and Yanming Xie

    Citation: BMC Complementary and Alternative Medicine 2017 17:108

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  15. Content type: Research article

    Acupuncture treatments that regulate the heart are used to treat various clinical disorders and conditions. Although many studies have been conducted to measure quantitatively the effects of acupuncture, thus ...

    Authors: Haebeom Lee, Hyunho Kim, Jungkuk Kim, Hwan-Sup Oh, Young-Jae Park and Young-Bae Park

    Citation: BMC Complementary and Alternative Medicine 2017 17:101

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  16. Content type: Research article

    Type two diabetes is a complex and demanding chronic disease and its impact in a state (Kerala) which leads India in terms of the number of people with Diabetes is profound. Though the male to female ratio amo...

    Authors: Aswathy Sreedevi, Unnikrishnan Ambika Gopalakrishnan, Sundaram Karimassery Ramaiyer and Leelamoni Kamalamma

    Citation: BMC Complementary and Alternative Medicine 2017 17:100

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  17. Content type: Research article

    Nutrition plays an important role in prevention and management of cardiovascular diseases (CVD) in early stages. Recent research demonstrated beneficial effects of various nutritional ingredients on vascular h...

    Authors: Claudia A. Reule, Birgit Goyvaerts and Christiane Schoen

    Citation: BMC Complementary and Alternative Medicine 2017 17:92

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  18. Content type: Research article

    Mind-body practices such as yoga have been studied for their generally positive effects on health-related quality of life (HRQOL). The association between how a person practices yoga and the person’s HRQOL is ...

    Authors: Gurjeet S. Birdee, Sujata G. Ayala and Kenneth A. Wallston

    Citation: BMC Complementary and Alternative Medicine 2017 17:83

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  19. Content type: Research article

    Many previous studies of electroacupuncture used combined therapy of electroacupuncture and systemic manual acupuncture, so it was uncertain which treatment was effective. This study evaluated and compared the...

    Authors: Bong Hyun Kim, Kyuseok Kim and Hae Jeong Nam

    Citation: BMC Complementary and Alternative Medicine 2017 17:85

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